Xin Zhou Lab
@xinzhoulab
Lab at @DFCI_ChemBio @HMS_BCMP | the Dale F. Frey Scientist @DamonRunyon | Protein and Cell Signaling Engineers
We are excited to share our lab’s first research article! rdcu.be/dU5AC We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. nature.com/articles/s4158…
We absolutely loved seeing this video explaining our TransTAC technology for targeted membrane protein degradation!! Hoping TransTAC opens doors to new cancer therapies and more!
Dana-Farber’s Xin Zhou, PhD, devised a new platform for potential cancer therapy that destroys cancer-driving proteins. Learn more: bit.ly/48K0Rg4
Can we recruit transcriptional kinases to activate gene expression? New in @sciencemagazine my first postdoc work developing CDK-TCIPs, a new inducer of proximity. We wondered if P-TEFb could be redirected to activate genes of interest. science.org/doi/10.1126/sc… . #ScienceResearch
New from the @brian_b_liau Lab, two papers in @Nature that reveal a chemical-genetic convergence #chemtwitter #CancerResearch
Today in @Nature we share our back-to-back stories with @nzhenguw revealing chemical-genetic convergence between a molecular glue & E3 ligase cancer mutations. 1/6
1/3 Today, an anecdote shared by an invited speaker at #NeurIPS2024 left many Chinese scholars, myself included, feeling uncomfortable. As a community, I believe we should take a moment to reflect on why such remarks in public discourse can be offensive and harmful.
One of my newest adventures - hosting a podcast! If you are keen on chemical biology, medicinal chemistry, chemical probes, tool compounds, degraders, chemoproteomic tools, and more... tune to @Target2035 podcasts. Pilot episode is out... more to come! podcasters.spotify.com/pod/show/targe…
Xin Zhou, PhD, a researcher at Dana-Farber and her team have developed a new platform that repurposes a cancer cell's own refueling mechanism to degrade proteins driving tumor growth. This breakthrough could reshape how we approach cancer treatment. blog.dana-farber.org/insight/2024/1…
Congratulation on a beautiful paper @xinzhoulab!!!
We are excited to share our lab’s first research article! rdcu.be/dU5AC We have developed Transferrin Receptor Targeting Chimeras (TransTACs), a novel class of heterobispecific antibodies designed for targeted degradation of membrane proteins. nature.com/articles/s4158…
Love this approach @xinzhoulab Transferrin receptor targeting chimeras for membrane protein degradation | Nature nature.com/articles/s4158…