stephen mchugh

Our new study is out in @NeuroCellPress: “Offline hippocampal reactivation during dentate spikes supports flexible memory”, with David Dupret and fantastic group at @MRCBNDU, @NDCNOxford authors.elsevier.com/sd/article/S08… #NeuroTwitter #hippocampus #pubalert 🧵 (1/9)

Hippocampal ripples during offline periods predict human motor sequence learning. Work led by the brilliant @PinChun_Chen. biorxiv.org/content/10.110…

Im pleased to share our new work, “Spatio-temporal organization of network activity patterns in the hippocampus”, now out in @CellReports! With Demi Brizee & David Dupret, we track how rhythms and spiking behavior map onto hippocampal layers. doi.org/10.1016/j.celr…

Excited to share our preprint led by @ainchung & Jason Alipio showing how few immature adult-born DGCs preferentially recruit inhibition of CA2 and CA3 to disproportionately affect hippocampal network properties and social memory. We began by asking 1/n biorxiv.org/content/10.110…

Why academia is sleepwalking into self-destruction. My editorial @Brain1878 If you agree with the sentiments please RT. It's important for all our sakes to stop the madness academic.oup.com/brain/issue/14…

Interested in the utility of EEG for early / differential diagnosis of dementia? Check out latest preprint from our unit (tinyurl.com/22xrzaz4): medrxiv.org/content/10.110…

Temporal structure of experience etched on firing of human hippocampal-entorhinal neurons to serve memory & prediction. See our study @Nature at @UCLANsgy, great work by lead author @PTacikowski with @GuldamlaKalendr & @DavideCili support @NIH_NINDS. nature.com/articles/s4158…

Our new paper shows #psilocybin has similar long-term antidepressant effects as the #SSRI escitalopram but leads to greater improvements in psychosocial functioning, connectedness, and life meaning. Published in Lancet @EClinMedicine. thelancet.com/journals/eclin… 🧵1/10

As part of #WorldAlzheimersMonth, we spoke to @marcaurelbusche, Group Leader at @UKDRI about his research, which he hopes will aid in the development of Alzheimer's disease treatments that are both safer and more effective: bit.ly/4cZWhes #UCLDementia

New unit paper by McHugh et al. from Dupret group provides novel insights into a type of neural activity that helps nerve cells work together during sleep for making new, adaptable memories, published in @NeuroCellPress! mrcbndu.ox.ac.uk/publications/o… @NDCNOxford @UniofOxford

Please see our preprint here: biorxiv.org/content/10.110…

Q: if monoclonal antibodies for Alzheimer's were available now, how many people in the UK would be eligible? A: 30,200 people/yr (less than expected) applying trial criteria to real populations in Cambridge + South London. Read our paper here ⬇️ bit.ly/addemand