stefan.schattgen

Scientists found T-follicular helper cells determine the effectiveness of vaccine-induced flu immunity. Research suggests an improved method for developing flu vaccines that would increase efficiency and prevent helper cell-mediated suboptimal responses. ow.ly/uIYl50T2fE0

Thrilled to share our preprint! We introduce TCRAFT, a method to assemble tens of thousands of TCRs at <$1 each, unlocking high-throughput functional TCR screening from single-cell data. 🧵@kochinstitute @MEBirnbaum @MITChemE @MIT biorxiv.org/content/10.110…

Very sad to hear that UMass is rescinding all PhD admissions for Fall 2025. This means there will be no new PhD cohort, and UMass will not have a graduating class that year. This is just unprecedented and I am so very sorry for all the affected students.

Researchers in Science #Immunology have identified CD8+ T cells from human donors that can recognize naturally occurring influenza variants spanning more than 100 years, including the 1918 influenza A and 2024 #H5N1. @Jamie_Rossjohn @kedzierskalab scim.ag/4hpSzh1

Our work on contrastive learning of T cell receptor representations is now out in Cell Systems! Give SCEPTR embeddings a try for your TCR analysis applications: sceptr.readthedocs.io/en/stable/

If you are interested in HLA, adaptive immunity, or viral infections, please see the special issue I am guest editor for: mdpi.com/journal/viruse…

Read more about the #HighlyCited2024: ow.ly/QPCz50UalMt

Finally out: Characterizing T cell specific responses to vaccine and infection in HLA-DPB1*04-restricted patients across 4 time points. Thank you Philip Mudd and Ali Ellebedy for inviting me into this amazing data set. Paper: nature.com/articles/s4159…

One month to go until the London Quantitative Immunology Day on March 14th! Submit your abstract in the next two weeks to be considered for a contributed talk 👉 qimmuno.com/ldnday/