Sridevi Rajeeve, MD
@sridevirajeeve
⚕️Asst. Attending Myeloma & Cell Therapy @MSKCancerCenter via @MountSinaiNYC @TischCancer 🇮🇳➡️🇺🇸 Interests: #MMsm #CART #cellulartherapy
Amazing evening receiving the @ASCO @ConquerCancerFd Young Investigator Award (YIA) 2022. Thankful to my stellar mentor Dr. Samir Parekh at @IcahnMountSinai & @TischCancer @SinaiHemeOnc for the support! #ASCO22 📸3: friends, old and new @drsomedeb 📸4: proud hubby @suchithnair




Guidelines for the testing and reporting of cytogenetic results for risk stratification of multiple myeloma: a report of the Cancer Genomics Consortium Plasma Cell Neoplasm Working Group [Jun 18, 2025] Lu et al. @lbaughn @BloodCancerJnl nature.com/articles/s4140… #mmsm #hemepath…
Happy to share our new work out today on @BloodPortfolio #Blood where we report CD38 loss as recurrent mechanisms of resistance to anti-CD38 antibody in multiple myeloma. Great collaboration between @MSKCancerCenter @MSK_DeptOfMed @UCalgary @HDMyeloma @MayoClinic #mmsm #wgs
We call for a paradigm shift in development of immunotherapy drugs, especially bispecifics. @LeukemiaJnl These drugs have therapeutic effects that last a long time. We need to reduce frequency and switch to limited duration treatment to avoid toxicity. nature.com/articles/s4137…
Early results in patients who had failed prior CAR T: → 81% overall response → 52% complete remission at 3 months → 3-day manufacturing turnaround This research from @carlhjune and team represents the first IL-18–secreting CAR T tested in blood cancer — and it may reshape…
For patients with lymphoma that relapses after CAR T, clinical options become vanishingly few. Now, a new study in @NEJM led by @carlhjune, Director of the PICI Center @PennMedicine, offers a new approach: huCART19-IL18 –– an IL-18–secreting, “armored” CAR T-cell.…
Dr. @RahulBanerjeeMD from @fredhutch talks on #Cevostamab: A “third-party candidate” in myeloma? ✅ FcRH5 target, maintained post-BCMA exposure ✅ Manageable safety, fewer infections vs. BCMA bsAbs ✅ No GPRC5D toxicities ⏳ Needs better efficacy/durability! #DAVAWhistler
Looking forward to the inaugural #iwGPRC5D International Workshop on GPRC5D-Targeted Myeloma Therapies on March 22 in NYC! iwgprc5d.org/agenda/ Excited to learn & share our collective knowledge on the next frontier beyond BCMA. @szusmani @ShamMailankody @NoopurRajeMD ...

So excited!! Welcome @UrviShahMD to @fredhutch Grand Rounds. I’m glad you joined by Zoom since shockingly it is raining today in Seattle for the first time in 2 weeks :) Cc @MSKCancerCenter @szusmani @sridevirajeeve @GunjanLShah @MScordoMD #MMsm
MSK is the first hospital in New York City to offer gene therapy for #sicklecelldisease and beta thalassemia through its pediatric program, MSK Kids. “Following our leadership in gene therapy clinical trials, this authorization expands our treatment options for these…
Congrats to @RahulBanerjeeMD @VincentRK @szusmani @Myeloma_Doc @myelomaMD et al for this extremely clinically impactful paper! #mmsm ashpublications.org/blood/article/…
#ASH24 📊: Daratumumab vs lenalidomide maintenance in NDMM TE+TI, 1:1 randomized IIT @MSKCancerCenter. n=87 (39 dara, 38 len). Similar (numerically ⬆️) 12mPFS, 24mPFS, >=CR & MRD- rates with fewer drug discontinuation on dara arm. 66% prior dara exposure. @UrviShahMD @szusmani




Just out: Paradigm changing AQUILA randomized trial in high risk smoldering myeloma #ASH24 @thanosdimop @NEJM Daratumumab significantly prolongs time to active myeloma and overall survival. Proud to be a lead investigator of this trial nejm.org/doi/full/10.10… Slides in thread
Out in @NEJM as @thanosdimop is speaking!! 🚨 Most important #ASH24 abstract in #MMsm: AQUILA study demonstrating OS benefit with dara x3 years in high-risk SMM. Monthly dara now can prevent Dara quad & ASCT later? Will be worth it in some patients! nejm.org/doi/full/10.10…
1/ Easily the most provocative #MMsm oral abstract of #ASH24 🤔 Does transplantation interfere with subsequent CAR-T efficacy? Gustine et al @andrew02114 @NoopurRajeMD Part 1 - setting the stage Why high-dose melphalan might interfere with T-cell fitness…
What happens when patients with myeloma and sustained MRD negativity choose to discontinue maintenance? We sought to answer this question in our study MRD2STOP, out now in @BloodCancerJnl nature.com/articles/s4140…
Join myeloma specialist Dr. Kylee Maclachlan for the presentation "Genomic Complexity Correlates with the Degree of Marrow Independence of Malignant Plasma Cells in the Context of Extramedullary Disease." 2:15 pm PST at #ASH24. @MSKCancerCenter @szusmani buff.ly/4f6J3gP
Hot off the press in @BloodCancerJnl Salvage therapy for post CAR T relapse: Are BiTES the right choice? n=139 (mostly idecel), relapse <5m,>50% EMD RR:Talq (80%), Tec (65%), IMiD/PI/CD38 (30%),Other (25%) ⬆️⬆️DoR, PFS, OS w BsAb vs Others regardless of EMD, timing of relapse.