Shahar Sukenik
@shaharsu
alternating between running my lab and taking care of the kids. Tweets my own and mostly science-related.
📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes. shorturl.at/U5VS1
📢 Excited to share our research with @shaharsu & @mvstaller on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions regulate transcription in unique ways. doi.org/10.1101/2024.1… 🧵 Highlights:
New work from @eflores500 examines the relationship between disordered ensemble structure and activity in transcription. Read more here 👇
📢 Excited to share our research with @shaharsu & @mvstaller on how activation domain (AD) structure affects gene expression! 🧬 TLDR: HIF-1α & CITED2 ADs suggest ensemble dimensions regulate transcription in unique ways. doi.org/10.1101/2024.1… 🧵 Highlights:
It has been more than four years since @alexholehouse and I started @IDPseminars and now it is time for fresh blood and fresh ideas! We are happy to announce that @chemeslab and @PelhamJackie take over as hosts!
We (@alexholehouse and @ProteinMagnus) started IDPSeminars in May 2020. It has been a wonderful platform to host an incredible array of international science. What began as a pandemic alternative to conferences has blossomed into a consistent and supportive community.
Big news - IDPSeminars has new hosts 🥳🎉!
We (@alexholehouse and @ProteinMagnus) started IDPSeminars in May 2020. It has been a wonderful platform to host an incredible array of international science. What began as a pandemic alternative to conferences has blossomed into a consistent and supportive community.
Check out this fascinating blend of cutting-edge structural proteomics and proteome-scale adaptation to the extreme. I am honored to have contributed to this fantastic collaboration, which provides insight into intrinsic desiccation tolerance in yeast proteins!
📢New paper alert!! With @boothbylab @alexholehouse @fried_lab we take a look at how an entire proteome survives desiccation. TLDR: Desiccation tolerance is encoded in specific residues on the protein surface, and occurs primarily in biosynthetic enzymes. shorturl.at/U5VS1
And that's a wrap for IDP GRC 2024🍝!! Thanks to all sponsors, speakers, GRC staff, and amazing attendees for making the 2024 meeting so memorable! Special thanks to our fearless chairs @TanjaMittag and @BBKrage!
Returning from @GrcIdp collecting droplets. Grateful for belonging to a community where both science and people matter. Thrilled to have done this with @TanjaMittag and for handing over to @shaharsu and @xsalvatella1
Congrats to the best poster award winndes at IDP GRC 2024🏅🍝: Lucia Alvarez (EMBL) Maria Correia Davis (Aarhus) Marcos Gil-Garcia (ETH) Atar Gilat (WIS) Charlotta Lorenz (Cornell/Zurich) Jeff Lotthammer (WashU) Adam Rubin (MIT) Min Kyung Shinn (WashU) Please RT and tag!
First, Elizabeth Rhoades of @LaserSharkLab who will be a faculty mentor and serve on the IDP GRS Navigating the Funding Landscape panel!
Our next IDP GRS faculty mentor and "Navigating the Funding Landscape" discussion panelist is @DanfengCai
For anybody still interested in learning what makes proteins fold and unfold slow or fast, read our recently published work on massive rate accelerations of CI2 by targeted mutations that do not change stability
Are you excited for the upcoming IDP Gordon Research Seminar/Conference starting this weekend? We are! To get things started for the GRS we will be highlighting some of the panelists and mentors attending the GRS! Get your questions ready for the panelists and prepare to network!