Jonathan Sebat
@sebatlab
From DNA to the brain. Occasionaly fatherhood, cycling, indie rock. No, Dad will not turn his music down.
On behalf of the CNV analysis workgroup of the @PGCgenetics I'm pleased to share our latest paper "Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects" 🧵1/N medrxiv.org/content/10.110…
Our latest paper (since last week), Long read WGS boosts detection of causal variants. But long reads are a game changer WRT to resolving complex genetic variation and its functional consequences and regulatory effects. medrxiv.org/content/10.110…
Congrats to @McKnightFdn 2025 Neurobiology Brain Disorder awardees: @hyejung_won @SharmaLab_UCSC @Allan_HPool @ZucheroLab @EthanHughesLab. Honored to be on the selection committee. So many amazing applicants this year focused on brain disorders.
Something that is prob not known to PIs outside the US: we have to cover our salaries from grants. At med schools, usually 50-99% of it. Even teaching positions only cover 9 months salary. So you need to find ~$100-200k/year JUST for your own salary. Thus needing multiple grants.
Sweden: one per year, and you cannot have more than one grant at the same time