Andrej Sali lab
@salilab_ucsf
Integrative protein structure modeling group of Andrej Sali @UCSF @UCSF_BioE @ucsfpharmacy @QBI_UCSF | Tweets are views of lab members.
Proud to share the result of an amazing collaboration with Javi Fernandez-Martinez, @RoutLab_RU , and @TheVillaLab ! biorxiv.org/content/10.110… Congrats to @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech and the team! And check out the video by @neeleshsoni03 ! #NPC
We are excited to share our new spatiotemporal integrative model of nucleocytoplasmic transport by the NPC, led by @BarakRaveh, in collaboration with those at @IntActOme including the labs of @DavidCowburn1, @RoutLab_RU, @TheVillaLab, and Roderick Lim: biorxiv.org/content/10.110…
New year, new manuscript! Our work on mapping transport between the nucleus and the cytoplasm is now on BioRxiv, and it's time to embark on a journey through the nuclear pore complex. Nuclear what? Bear with me! biorxiv.org/content/10.110…
Navigating the seas of science and the waters of Tomales Bay! Having a blast at the lab retreat.
🎉Celebrating our latest publication on the NPC basket structure in Cell cell.com/cell/fulltext/…!
We are excited to share our most recent preprint with the @EllenbergLab. We developed a new, integrative method for modeling spatiotemporal systems and applied it to study NPC Assembly: biorxiv.org/content/10.110…
From preprint to journal. Our nuclear gatekeepers have successfully unlocked the gates to Cell (Journal) cell.com/action/showPdf… #NPC #integrativemodeling Congrats to team @dgvjayS @JoshHutchings94 @ig_ech @RoutLab_RU @salilab_ucsf @TheVillaLab Animation youtube.com/watch?v=LiKdFI…
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling biorxiv.org/content/10.110…
Tiny gatekeepers of our nucleus decide what gets in and out. Follow our study on Yeast and Mammalian NPC baskets and unravel the molecular structure of these cellular bouncers! Don't miss the side-by-side comparison in the video. #IntegrativeModeling biorxiv.org/content/10.110…
Proud to share the result of an amazing collaboration with Javi Fernandez-Martinez, @RoutLab_RU , and @TheVillaLab ! biorxiv.org/content/10.110… Congrats to @dgvjayS @neeleshsoni03 @JoshHutchings94 @ig_ech and the team! And check out the video by @neeleshsoni03 ! #NPC
Diverse multiresolution data & an ensemble of heterogeneous models, can you imagine a better setup for the #IntegrativeModeling?) Great collaboration led by @DrMartyTaylor & Donna Romero @rome_tx, @macro_momo, @RoutLab_RU, @bengrbm, Eddy Arnold, Matthias Götte & @KathleenHBurns
So excited to share our story revealing structures, functions and adaptations of the human LINE-1 retrotransposon, an ancient genetic parasite that has written 1/3 of the human genome and is implicated in cancer, aging, & autoimmunity. Now out in @Nature nature.com/articles/s4158…
New paper in @Nature by @ShotaroOtsuka, the @EllenbergLab @embl and @salilab_ucsf! The scientists reveal how the individual components of the nuclear pore complex assemble one protein at a time. Read more: tinyurl.com/bdehmx89 Paper: tinyurl.com/4rhp37ks @MedUni_Wien
We stand in solidarity with postdocs and graduate students in their bargaining with the University of California. We fully support a lawful and fair bargaining process. We believe that researchers should think about their science, not how to pay rent.
We @QBI_UCSF @salilab_ucsf are recruiting 6 #postdoc in #computational #structuralbiology to work with multi-disciplinary teams @CancerCellMap of systems & structural biologists, as well as infectious disease experts! For more info check salilab.org/positions/pd_q…
We are hiring for a computational structural biology postdoc to work on collaborative projects with RCSB PDB; see salilab.org/positions/pd_r…
Comprehensive structural analysis of #NPC, using a slew of techniques including #SPA, #insitu #cryoET & #IntegrativeModeling. Great collaboration between Akey, Rout, @TheVillaLab, @sludtke, & @salilab_ucsf labs, led by Chris, Christna,@ig_ech & me. A🧵biorxiv.org/content/10.110… 1/n
'This virus will ultimately become endemic': Scientists find key in alpha variant to fight omicron @KroganLab @QBI_UCSF abc7news.com/health/scienti… via @abc7newsbayarea
Excited to share our new comprehensive structural analysis of the #NPC, using #cryoEM, #insitu #cryoET & #IntegrativeModeling. Great collaboration between Akey, Rout, @TheVillaLab, @sludtke, & @salilab_ucsf labs, led by Chris, Christna, @dgvjayS & me biorxiv.org/content/10.110… 1/n
Comprehensive structural analysis of the yeast #NPC, using #cryoEM, #insitu #cryoET & #IntegrativeModeling. Great collaboration between Akey @IntActOme, Rout, @TheVillaLab, @sludtke and @salilab_ucsf labs, led by Chris, Christna, @dgvjayS & @ig_ech biorxiv.org/content/10.110…