Rebecca Buller
@rebeccambuller
How has #biocatalysis evolved in the past 5 years? Our just-published review in @ScienceMagazine highlights how powerful technologies have enabled scientists to dream up bold new-to-nature activities and bring them to biocatalytic reality. Curious? 👉science.org/doi/10.1126/sc…

Super happy that EnzyMS, our LC-MS pipeline for detecting promiscuous #enzyme activity, is out in @ChemCatalysis ! Testing it on WelO5* + soraphen A uncovered an oxidative demethylation - missed by standard tools. Curious? 👉 cell.com/chem-catalysis…

Inspirational morning session at #Biotrans2025 with contributions on NRPS engineering by @HelgeBode_Lab and new peptide-modifying enzymes by @piel_lab . This was followed by fantastic oral communications by M. Schürmann, G. Xu, V. Willers,@KouristLab and K. Steiner.

#Biotrans2025 is off to a fantastic start! A big thanks to the > 600 #biocatalysis enthusiasts that made their way to Basel. The opening ceremony was made truly special by inspiring lectures from @erblabs and @Turner_Biocat and beautiful protein tunes by Nora Eifler!

What a wonderful stay in beautiful Edinburgh to share some of my group's science with the @EdinburghUni colleagues. Many thanks to Amanda @ArtOxiZymes and Dom @CampopianoGroup for the invitation and making my stay truly memorable! #enzyme_engineering #biocatalysis

#Computational_Analysis reveals a surprise: FAST-#PETase rigidifies at high temps, boosting stability, instead of becoming more flexible. This helps explain FAST-PETase’s thermostability and could help guide the design of temp-tuned enzymes! Curious? 👉doi.org/10.1016/j.csbj…

Exciting new chapter ahead: Thrilled to join @unibern @DCBPunibern as Full Prof of Organic Chemistry in Sept! 🎉 Huge thanks to my amazing team, colleagues & mentors for an incredible #biocatalysis journey. Looking forward to new enzyme adventures🚀! 👉mediarelations.unibe.ch/personalia/202…

It's this time of the year....🎄🎄🎄 A big thank you 🙏 to the wonderful CCBIO team, past and present, for the truly wonderful collaboration! Happy holidays! ✨

Excited to share our Highlight in @AngewandteChemie honoring the 2024 #NobelPrize 🏆 to David Baker and Demis Hassabis/John Jumper in which we explore how computational tools are transforming medicine💊, diagnostics🔬 and sustainable manufacturing🌿. 👉doi.org/10.1002/ange.2…

Scientific Leaders of the next Generation! 🔔Only 10 days left to apply as a JSP participant for the SCS Bürgenstock Conference 2025 🗓️May 4-8 Brunnen, Switzerland apply now: bc25.scg.ch/jsp-program #bc25 #jsp #scs #switzerland #symposia
Registration / Abstract submission for Biotrans2025 in Basel is now open! Please spread the word. 👉biotrans2025.com

We are really happy to announce that Prof. Paolo Melchiorre @Melchiorre_P will be the vice-president of the Bürgenstock conference 2025! The program – always kept as a secret – was assembled by Prof. Mascareñas as president and the organising committee, and features outstanding…
Interested to apply lactam and cyclic imide hydrolyzing enzymes🌱? In our @ACSCatalysis review, we explore the hydrolytic biocatalysts and provide a broad protein database to accelerate enzyme discovery. 🧬🔍 👉pubs.acs.org/doi/10.1021/ac… 👉github.com/ccbiozhaw/Cycl… @NCCR_Catalysis

Congrats🎉 to Lisa Schelbert for winning the Lab Sciences Award 2024 🎖️for her BSc thesis on the fitness landscape 🏔️of engineered Kemp eliminases. Grateful for the privilege of having mentored her and looking forward to seeing what she's up to next! #ProudPI @NCCR_Catalysis
Accelerating enzyme engineering: In @nchembio we show that by removing destabilizing mutations from sequence space we generated a🚀Kemp eliminase in only 5 evolution cycles! Recombination charts the designer enzyme's fitness landscape🏔️. 👉nature.com/articles/s4158… @NCCR_Catalysis

Thanks so much for this recognition!
Now it’s the time for the President @Luc_Van_Hijfte to award the winners of the @EuroMedChem Prizes for Young Medicinal Chemist or Chemical Biologist: for Academia, the winner @rebeccambuller gives the Prize lecture on Engineering Aliphatic Halogenases. #EFMCISMC24 @ChemMedChem
Super happy & honored to receive the #biocat2024 award🎉 ! Huge thanks to the organizers & selection committee, my amazing team, and all who’ve supported me along the way. Excited for what’s ahead in our journey to push the boundaries of #biocatalysis🧬🧪🌿! @NCCR_Catalysis @ZHAW

What a fantastic day in the Swiss mountains with the CCBIO Team!

Excited about engineering powerful biocatalysts? Check out the open PhD position in my group! 👉zhaw.ch/en/jobs/vacant… Please spread the word!🇨🇭🏔️🧪🌿☀️ @NCCR_Catalysis @ZHAW Photo: ZHAW Wädenswil / Frank Brüderli
