The Sapieha Lab
@psapieha
We are interested in retinal and vascular aging and how it influences neuroinflammation.
We are thrilled to share our study on the role of cellular #senescence in #diabetic macular edema and clinical data for the first #senolytic developed for the eye . Congrats @SerCresGar and @UnityBiotech! @UMontreal @NatureMedicine @CellSenResearch nature.com/articles/s4159…
Happy to share our latest publication on the phase 2 BEHOLD trial that evaluated effects of our senolytic drug candidate UBX1325 in subjects with diabetic macular edema. #diabetes @UnityBiotech @ARVOinfo @NEJMEvidence @aao_ophth evidence.nejm.org/doi/full/10.10…
🚨We are hiring!🚨 We have postdoctoral positions available! If you're passionate about studying cardiac regeneration and development, join our team in vibrant and beautiful Montreal! Please help spread the word 🫶 For more details see here research.chusj.org/RECHERCHE/fi...
Marcin Patrzalek plays Beethoven's 5th symphony perfectly on his guitar. 👌
We’re excited to welcome Federico Grossi, M.D., Ph.D. as our new chief medical officer. He brings a wealth of experience in clinical and regulatory strategy and will support the clinical development of our lead candidate UBX1325. $UBX ir.unitybiotechnology.com/news-releases/…
Happy to share our study on the beneficial role of the innate immune system on vascular remodeling in retinal disease and potential negative impact of steroids. @MasayukiHata7 @UMontreal @ARVOinfo @CIHR_IRSC @_BrightFocus @AmDiabetesAssn @iserworld pnas.org/doi/10.1073/pn…
The best part of research are the awesome people we get to work with. Happy Holidays from the @psapieha
Important work from the @CraigEdBrown lab implicating high levels of IL10 in reduced cerebral blood flow associated with cognitive decline.
Pleased to share our new paper implicating #interleukin 10 in perturbed #brain #microcirculation and #cognitiveimpairment in mouse model of type 1 diabetes. Congrats to the team @uvic, @sharmasorabh88, @UVicMedSciences, @NatMetabolism, nature.com/articles/s4225…
1 month until The Longevity Summit 2024 Speakers include: @LongevityGL @TheWebbLab @Charlesnduka @DrGlorioso @agingdoc1 @furmanbios @EricVerdin @HanadieYousef @j_n_justice @jpoganik @miRNAgirl @madcule @psapieha @_woman_founder @RonjonNag liveforever.club/events?selecte…
Join us!
Join us on Oct 15 for our Ophthalmology Day event — available virtually and in-person in New York, NY. Hear from top #ophthalmology experts & UNITY’s team on the latest in our DME program, followed by a live Q&A. Register here: bit.ly/3XpnuCP $UBX
Huge thanks to @E_v_a_Kaufmann for being a tremendous host and faculty of @QueensUHealth for enriching discussions.
Fascinating presentation and very inspiring talks with our Plenary guest Dr. Mike Sapieha @psapieha at Queen’s University this week @QueensUHealth Lots of hope and potential in ocular immunology 🤩 !
The Olympic Cauldron was lit with a burning arrow on this day at Barcelona 1992. 🔥 As archery kicks off today at #Paris2024, we're throwing back to that unforgettable moment.🏹✨ @worldarchery
Congratulations to @MasayukiHata7 for winning the « Prix Relève étoile Jacques-Genest « @ARVOinfo @med_umontreal @ciusss_estmtl @_BrightFocus nouvelles.umontreal.ca/article/2024/0…)
Our Chief Scientist Mike Sapieha, Ph.D. joined the @DrugDiscovNews DDN Dialogues podcast with host @sci_steph to break down our senolytic model and #UBX1325’s recent clinical trial success in improving vision and eye health in patients with #DME. bit.ly/3VBfCf7
Happy to share our study demonstrating an important role for the immune system in pruning pathological neovascularization in retinopathies and potential caution for broad spectrum anti-inflammatory drugs.@MasayukiHata7, @CIHR_IRSC @ARVOinfo @aao_ophth biorxiv.org/content/10.110…
Arrival at the #innateimmunity @AegeanConf in Loutraki Greece. Great group of scientists here.
Congratulations to @SerCresGar of @UMontreal - the latest winner of our $500 Early Career Scientist Grant! 🎉 Find out how he plans to spend his $500 grant & apply for our next grant here: ow.ly/e6q350ROz7A #lifescience #earlycareerscientist #sciencefunding #postdochelp
Dear network, our lab at the @umontreal is searching for motivated graduate students and postdocs. Please share, and you can email or DM me for more info! 😁#Recruiting #Hiring #RecruitingGraduateStudents #RecruitingPostDocs #RetinaCellBiology #VascularBiology #Neuroscience
Huge congratulations to @MasayukiHata7 for winning a prestigious Brain Star Award from @CIHR_IRSC ranking in the top 3. Phenomenal work and achievement by an extraordinary clinician-scientist. can-acn.org/brain-star-awa… @CAN_ACN @_BrightFocus science.org/doi/10.1126/sc…