Patricia Nano
@prnano9
Postdoc @BhaduriLab | human brain development + single-cell omics
It’s out! The first paper from my postdoc – and first from the @BhaduriLab – is now live @NatureNeuroscience. 🧠✨ (1/5)
Parallel meta-analyses of the human cortex in development (seven datasets) and adulthood (16 datasets) generated over 500 gene co-expression networks describing of cortical development, centering on peak stages of neurogenesis @BhaduriLab @prnano9 nature.com/articles/s4159…
🧵Excited to share our new preprint introducing iHOTT - an autologous tumor-immune co-culture model that captures patient-specific responses in #Glioblastoma 💥Now on @biorxivpreprint: biorxiv.org/content/10.110… 📝From @BhaduriLab in collaboration with @UCLANsgy
Excited to present our new preprint led by @claudianguyen95 uncovering how thalamic input shapes human cortical development! We discover that thalamic axons promote upper layer cortical neurogenesis through NRXN1-mediated contacts with outer radial glia. biorxiv.org/content/10.110…
Delighted to share our most recent preprint led by the incredible @MilJessenya and @Jalbsoto! In this study, we generated a metabolomic atlas of human cortical development and discovered that the pentose phosphate pathway regulates radial glia cell fate. biorxiv.org/content/10.110…
Very excited to present a @bioRxiv paper from our lab on our human organoid tumor transplantation (HOTT) system to study glioblastoma! This work was led by the very talented project scientist Dr. Weihong Ge + exceptional graduate student @RyanKan20 (1/18) biorxiv.org/content/10.110…