Peder L. Myhre MD, PhD
@pmyhre
Professor of Cardiology @UniOslo_MED 🇳🇴 | Director @NorTrials Cardiovascular Center | @Brighamfellows alumni | Circulation On The Run podcast host @CircAHA |
🎧 What an inspiring listen by @pmyhre on tackling heart failure—from cutting-edge HF research to biomarker-driven care, global challenges of implementing digital health, and how Norway is reshaping participation in cardiology clinical trials. emjreviews.com/cardiology/pod…
Dr. @ankeetbhatt offers perspective on implementation science, “the scientific study of methods and strategies that facilitate the uptake of evidence-based practice and research into regular use by practitioners and policymakers." bit.ly/3oGbHeU #TransformCVCare
Absolutely thrilled about the recent regulatory clearances of our cardiac amyloidosis (CA) detection model. This is a game-changer in early CA diagnosis—bringing speed, accuracy, and scale to a condition that’s too often missed or delayed. Proud of the impact this will have!
🚨 Product Update: Us2.ai’s AI Echo Copilot™ is now FDA cleared + CE marked for cardiac amyloidosis detection! What makes it unique? ✅ Combines 2 complementary approaches in one platform: 1️⃣ AI pattern recognition — detects from a single A4C view, validated…
Athlete’s heart vs. cardiomyopathy—where’s the line? 🫀 This review breaks down how to distinguish physiologic remodeling from early-stage hypertrophic, dilated, or arrhythmogenic CM using imaging. A practical guide to navigating the “gray zone” (link.springer.com/article/10.100…). #HREV
AF and HFpEF co-exist and drive CV risk. Managing AF in HFpEF requires an integrated approach—HF therapy, rhythm or rate control, and stroke prevention. There is a growing case for early rhythm control via ablation (link.springer.com/article/10.100…). #HREV @PaulaRambarat @JonPicciniSr
This is super interesting. Low ApoM seems to be a key player in HF/CKM. I think we will learn much more about this as a potential therapeutic target the next decade…
🚨Two new JACC Advances papers drop today linking SGLT2 inhibitors ↔ apolipoprotein M (ApoM) across very different settings—ambulatory HFrEF (DEFINE-HF) and acute inflammation (LPS-sepsis & COVID-19). Let’s unpack why this kidney-liver-vascular axis matters. A 🧵 1️⃣/15
#GDMTworks 🇳🇴
Marked increase in HFrEF GDMT in Norway (2016–2023), with 4× faster MRA uptake after 2021 ESC HF guidelines and ~50% reduction in HF hospitalisations since 2016. 📖 Full article: onlinelibrary.wiley.com/doi/10.1002/eh…
Obesity drives a unique, early-onset form of HFpEF—often underdiagnosed. Yet, no guidelines recommend screening. This review outlines why systematic screening in obesity is overdue and proposes a tailored approach (link.springer.com/article/10.100…). #HREV @JLHarrington_MD @FudimMarat
DOACs may offer a safer, simpler alternative to warfarin for LVAD patients—especially with HM3. This review explores emerging data, device-specific considerations, and the need for prospective trials to guide anticoagulation for LVADs (link.springer.com/article/10.100…). #HREV @ninoskills
We had the pleasure to host @mvaduganathan for a mini-tour of Oslo with talks for nephrologists (#NSN2025), cardiologists, grand rounds and a research seminar. A true leader in cardio-renal-metabolic disease and such a friendly guy! We are so grateful for your visit!🙏
This year’s summer seminar was one for the books with world class speakers @mvaduganathan and @oyvlie talking about the interaction between heart and kidney and how to interpret clinical trials! 🙏 thank you
#CONFIDENCE 1⃣ + 1⃣ = 2⃣ Remarkably, kidney protection with combination therapy mathematically identical to what would be expected based on each monotherapy Finerenone (0.68) * Empagliflozin (0.71) Combination (Expected if Fully Additive): 0.48 Combination (Observed): 0.48
2024 European blood pressure guidelines have sparked controversy, with their implications still unclear. We have applied these guidelines to a cohort study. Check it out @ESC_Journals @StrokeAHA_ASA @Tidsskriftet @escardio @ heart.bmj.com/content/early/…
Fantastic late breaker session at #HeartFailure2025 ‼️ 🇳🇴🇸🇪🇮🇹 doing really well on #GDMT uptake - especially after the 2021 @escardio guidelines, including improvements in outcomes 👏🏻 ⭐️⭐️⭐️ @BergeKristian @RInciardi #FelixLindberg




New data from EMPEROR-Preserved: patients with more severe diastolic dysfunction seems to experience greater benefit from empagliflozin! Highly significant interactions


Super interesting data from @safchat @scottdsolomon and #FINEARTS-HF: Consistent safety and efficacy of finerenone across the eGFR spectrum in HF, and seems more favorable with respect to safety in lower eGFR compared to spironolactone (TOPCAT)




Data from #FINEARTS-HF supporting the efficacy of EARLY initiation of GDMT following hospitalization for HF. @ankeetbhatt 💫 To be confirmed REDEFINE-HF: clinicaltrials.gov/study/NCT06008…

Selfie after birthday party @AlexMebazaa @lamcardio @KarenSliwa @pmyhre
Straight from a beautiful Norwegian national day celebration to Belgrade for @escardio #HeartFailure2025 ! Can’t wait to see all my HF friends and learn more. 📍Join us Tuesday 8.30 for a Late Braker registry presentation from 🇳🇴 @BergeKristian & 🇮🇹@RInciardi



Very important topic. Many cases of HFpEF are simply a deficiency disorder. A deficiency of exercise!! 🏃♂️
HFpEF is a growing public health burden with few proven therapies. Exercise training improves function, with modalities ranging from moderate-intensity to multi-modal and emerging options like IMT and FES. (link.springer.com/article/10.100…). @aepetersMD @JLHarrington_MD
Inflammation is central to development/progression HF. This review unpacks the role of immune pathways, biomarkers like CRP/IL-6, and comorbidities like diabetes and obesity—while exploring the promise (and limits) of anti-inflammatory therapies in HF (link.springer.com/article/10.100…).