A/Prof Paul Beavis
@paulbeavis4
Cancer Immunotherapist, collaborative researcher, founder of “team Beavo” & long suffering pommy cricket fan down under.
Fantastic to see this work led by @JunyunLai and @mardianasherlz published today. Culmination of many years work in two @PeterMacRes buildings! Look forward to developing this approach further.
Darcy, Beavis and colleagues use T cells engineered to express the dendritic cell growth factor Flt3L to co-opt the host endogenous adaptive immune response and control experimental tumor models. @unimelb @MacCullumCC @WEHI_research
Nature research paper: Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery go.nature.com/4le7GMB
Pleased to present the latest work from the lab published in @NatureComms in work led by @kevin_sek: nature.com/articles/s4146…
Dedicating my first post on X to share some exciting news — our work is out today in @Nature! 🎉 Co-first authored with the amazing lab buddy @_amandachen, and guided by our incredible supervisors @paulbeavis4, Phil & @ImranHouse. nature.com/articles/s4158…
In the news today: Peter Mac scientists have developed “Precision Guided Munition” CAR T-cells – smart immune cells that target solid tumours directly. In lab models, they wiped out breast, colon & ovarian tumours with cure rates near 100%! More: petermac.org/about-us/news-…