Paras Karmacharya
@paraskarmachary
Researcher-First. Minimalistic. Ethical AI + Timeless, Proven Clinical Research Systems | NIH-Funded Physician-Scientist @VUMCRheum | @MayoClinic alumnus
Want to identify research gaps and craft questions in minutes? I created a custom GPT for my research but over time it became so good that I thought I had to share it. Access it for FREE here: rising-researcher-academy.ck.page/research-idea-…
Most manuscript titles are terrible. ❌ Take a look at these titles: ↳ "You are too brash if you ignore the rash" ↳ "The red hearing" ↳ “Heart-stopping tick” ↳ “Touch me not” ↳ "All systems red” At first glance, they seem intriguing, right? But here’s the fatal flaw:…


I’ve tested 20+ AI tools for research. Only two were worth keeping. Tool-switching feels like progress - because distraction often does feel productive. In a world flooded with new AI tools and apps, it’s tempting to believe: “This next AI tool will transforms my research…

I kept getting ignored… until I stopped asking for permission. I sent dozens of cold emails to mentors, hoping for guidance. Polite. Eager. Well-crafted. Most of the time - Silence. The few responses I did get? A polite version of I don’t have anything for you. I was making…

Interviewing isn’t a test. It’s a performance - and most people forget their lines… I have seen brilliant researchers and clinicians fumble interviews. Not because they lack experience, but because they lack structure. STAR framework can change that. How it works—and how to…


NIH just cracked down on AI in grants. But their new policy leaves one huge gray zone - and it matters more than you think… The new policy is not just about compliance. It’s about strategy. Here’s what the new policy says: → NIH will not consider applications “substantially…


Your research program shouldn’t look like a thrift store clearance rack. Most early-career researchers don’t build a research program… They accidentally collect one. A paper here. A side project there. A dataset someone handed them at lunch. And suddenly, you have 5…


I thought I knew how to network. I’d go to conferences. Exchange emails. Add people on Social Media. I thought I was building a network—but really, I was just collecting contacts. Every conversation had a goal: ✅ Find mentors ✅ Get access to research ✅ Secure…


At some point, you’ll get that email. “Dear Dr. , I would be grateful if you could review a paper submitted for publication…” It’s flattering. It’s scary. It might even feel like a trap. So should you say yes? Here are 5 things I wish I knew early on: 1. Don’t say yes to…

Your literature review workflow is broken. The solution isn't more hours… it's automation. Most clinical researchers don’t have a system for staying up to date. They go in with good intentions… and end up 2 hours deep in a PubMed rabbit hole with 17 tabs open. I’ve been…



You spent 1,000 hours on your study. Don’t blow it in the 250 words that actually matter. Most researchers treat the abstract as an afterthought—something to dash off the night before submission. But here’s the truth: The abstract is the only section most readers (or AI) will…


Nearly every high-impact study starts the same way… by spotting one of these 3 gaps: 1️⃣ Gap in knowledge (we don’t know about it) 2️⃣ Gap in thinking (we’ve been thinking about it all wrong) 3️⃣ Gap in practice (we’ve not been applying it well) I break them down below 👇 ↓…


Finding the right mentor used to feel like shooting in the dark. Now, you can use AI as your radar - if you know how to ask the right questions. 4-step method to build effective collaborations with experts using AI 👇 ↓ ↓ ↓ Step 1: Let ChatGPT suggest potential mentors…


NotebookLM’s newest feature just gave self-learning a major upgrade. But here's the catch… It’s only transformative if you’re the kind of person who wants to learn. Because tools don’t build mastery. People do. And for the self-driven researcher, clinician, or academic……


If you wouldn’t submit a trainee’s draft without edits, why are you submitting AI’s? AI can save your writing process. But only if you know how to edit what it gives you. I see too many clinical researchers doing this wrong. They treat AI like a ghostwriter. Feed it a…


Long sentences are killing your writing. Every. Single. Time. → They’re hard to read. → They make your point confusing. → Worst of all? They lose your reader. 6 easy strategies that improve clarity: ↓ ↓ ↓ 1️⃣ The 25-Word Rule If a sentence crosses 25 words, break it…


Every scientist believes their writing is logical—until a reviewer tears it apart. And the problem isn’t usually the content. It’s the transitions. Perfect sentences can’t save a paper if the paragraphs don’t connect. Without transitions, even good science feels disjointed.…

"Should you aim for top-tier or mid-tier journals?" This is one of the most common questions my mentees ask me—and for good reason. In my early career, I made this mistake all the time: ↳ I sent every paper straight to NEJM, only to watch it trickle down the ranks. ↳ Often…

I use AI every week to critique my own work. But when it comes to peer review? I draw a hard line. I regularly use AI to internally review my own manuscripts and grants. It helps me break past my own blind spots. Reframe a fuzzy paragraph. Flag assumptions I forgot to…




Most research papers die with lack of self-leadership, not bad ideas. Good writing doesn’t comes from inspiration. It comes from leadership. But not the kind that leads others. The kind that leads yourself. Writing a great paper isn’t just about what you know. It’s about how…

Your mentor is tired of managing YOU. They want YOU to manage THEM. Managing up 📤: How to get what you want & give your mentor what they need… 1️⃣ Offer solutions, not just problems Mentors don’t want to be bombarded with problems—they want to see your ability to think…



