Oncogene Journal

A new insight into the association between #mitophagy and #BladderCancer progression. nature.com/articles/s4138… #OpenAccess

News from @AmelioLab: Advanced #SalivaryCancer and developing glands share common #p53 pathway regulation. Pro-tumorigenic FGFR2 distinguishes foetal development from high-grade MEC. nature.com/articles/s4138…

Research at @IBUB_UB found that combining Palbociclib and a Glutaminase inhibitor has a strong synergistic effect, preventing #resistance and significantly reducing tumor growth in #colorectal cancer cells. Read the article here >>>>> nature.com/articles/s4138…

A new article shows how tumor-associated #macrophages' extracellular vesicles drive regulatory T cell differentiation and #glioma progression, revealing potential new therapeutic targets for combating this type of tumor. Read now 🔗 nature.com/articles/s4138…

New study led by @EinsteinMed researchers reveals that CSF-1/CSF-1R signaling plays a crucial role in #breast cancer metastasis by regulating TMEM doorway function, offering potential new targets for treatments. Read now >>> nature.com/articles/s4138…

Researchers at @UofGCancerSci have discovered that trametinib #resistance in KRAS-dependent CRC is driven by the upregulation of the glucuronidation pathway. Read more 🔗 nature.com/articles/s4138…

New research reveals that the retinoblastoma #tumor suppressor pRB is crucial for skeletal muscle development and maintenance. Deleting Rb in myoblasts leads to #muscle degeneration and fetal death. nature.com/articles/s4138…

A new research suggests that combining cepharanthine (CEP) with anti-PD-1 therapy could enhance the effectiveness of #immunotherapy in MSS-type colorectal cancer, potentially improving patient outcome. Read now 📖 🔗 nature.com/articles/s4138…

Read how disrupting fatty acid oxidation impacts #bladder cancer. A new study identifies ACSL5 as an important regulator of tumor growth and senescence. Explore this! 🔬 nature.com/articles/s4138…

New study reveals that vimentin plays a crucial role in DNA #repair and lipolysis. Depleting vimentin leads to DNA #damage and impairs repair mechanisms. nature.com/articles/s4138…

Read how targeting PTEN neddylation can restore #tumor suppressor activity and overcome #resistance to palbociclib in breast cancer treatment. nature.com/articles/s4138…

You can read on the told of nicotinamide N-methyltransferase (NNMT) in driving #GastricAdenocarcinoma carcinogenesis in our latest issue: nature.com/articles/s4138…

Could targeting PTEN neddylation be a promising strategy for restoring tumour suppressor activity and overcoming resistance in #BreastCancer? nature.com/articles/s4138…

A novel mechanism by which cytosolic #mtDNA stress mediates TAM infiltration in #HepatocellularCarcinoma nature.com/articles/s4138…

Excited to share that I’m now part of the Editorial Board of Oncogene. I’ve long been a fan of the journal and look forward to contributing to its continued excellence #Oncogene #NaturePublishingGroup @oncogenejournal nature.com/onc/

Study revealing a small extracellular vesicle - #miRNA mediated mechanism governing tumour-macrophage communication in pancreatic neuroendocrine tumours nature.com/articles/s4138… #CancerResearch

A new promising therapeutic strategy for treating refractory #OesophagealCancer by targeting the NRF2 pathway in combination with receptor tyrosine kinase inhibition nature.com/articles/s4138… #OpenAccess

✅👉 Here our latest paper in @oncogenejournal with new functions for RAS-related protein R-RAS2 in primary mouse embryonic fibroblasts. @ciccancer @usal @csic @ASEICAnews @EACRnews @SmallGTPases ➕info below👇

Scientists may have unlocked the final frontier in medicine: PAUSING cell death. New research by @carinacarlakern et al - with contributions from @NASA, @ESA, @Mayo Clinic, and @Harvard — shows necrosis isn’t just the end of a cell. nature.com/articles/s4138…

LOXL2 as a druggable epigenetic target to overcome PARPi resistance in homologous recombination-deficient models of multiple tumour types. nature.com/articles/s4138…