#nicholslab

So so proud of this incredible Canadian AIrways Research (CARE) group collaboration @RJLin @peteryufanzeng ! 🙌🏽🙌🏽🙌🏽So much exciting iSGS research to come! @WesternOtoHNS @UnityHealthTO @UofT_OHNS

🚨 New #preprint alert! 🚨 Very proud to share our latest work unraveling treatment resistance mechanisms in anaplastic thyroid cancer (ATC), a rare but one of the most lethal human cancers, with survival measured in weeks for many patients. 🧵👇

A true pleasure to present our latest work on subglottic stenoses at #APSR24 in the beautiful HK 😍 Stay tuned for more coming 👀

Plot twist! The 5 year minimum follow up results of the ORATOR trial show that the MDADI curves converge mainly due to a decline in the CRT/RT arm at 5 years (later toxicity kicking in?!?) . Despite the title of the paper we are reconsenting patients to obtain 10 year follow up.

I have Asthma, allergies, dyslexia, ADD, anxiety, and Depression. But I will tell you that what you have does not define what you can become. Why Not You!

Last month our incredible student @peteryufanzeng defended his PhD. Congratulations Dr. Zeng! We hope you are enjoying your final months before starting clerkship! 💜🩺⚕️📓📈@nicholslab1

‼️🚨Happening now - HN oral abstracts #ASCO24 Much anticipated Ph3 IMPT vs IMRT for OPC presented by @SJFrankMD @MDAndersonNews A tremendous effort to complete this trial. 👋 IMPT non-inferior to IMRT in PFS, OS, superior in tox. @xrtGenomics @imrtlee @seanmmcbride @YaoCMKL…

🚨📢Happening now - HN oral abstracts #ASCO24‼️ PRACTICE CHANGING trial of hypoxia directed major radiation de-escalation as definitive treatment for HPV+OPC by @imrtlee @MSK_RadOnc @MSKCancerCenter, showing that 30Gy+Chemo is sufficient for cure, with > 500 pts treated so far.…

Our GATCI anaplastic thyroid cancer genomic dataset can now be accessed at @cbioportal cbioportal.org/study/summary?… We hope this resource can accelerate progress for the thyroid cancer community. @nicholslab1 @SchulichMedDent

I will be defending my #PhD thesis in 2 weeks. Please DM me for Zoom link if interested.

Thrilled to be working with @DropletBiosci and @DrCorreaRO head and neck cancer research projects!! @WesternOtoHNS @SchulichMedDent

Dr. Hussain Alsaffar joined us from Riyadh, Saudi Arabia as our distinguished guest alumnus, sharing thoughts on resiliency and residency. He was introduced by his former co-resident, Dr. Goran Jeremic. Welcome Dr. Alsaffar!

Thrilled to get this published. The FIND trial demonstrates the ability to reduce radiotherapy volumes after TORS for unknown primary. This includes the ability to spare the pharynx with subjective and objective improvements in swallowing: pubmed.ncbi.nlm.nih.gov/38602692/

Inspired and encouraged following the @CSCI_SCRC @CITAC_ACCFC annual joint meeting in Vancouver attended by several @SchulichMedDent MD/PhD students! We learned a ton from the incredible panels and mentorship sessions! 🩺🔬

Congratulations to @peteryufanzeng for his oral presentation award at the @CITAC_ACCFC conference for his work on anaplastic thyroid cancer genomics and targeted therapy! @Western_MDPhD @SchulichMedDent @WesternOtoHNS @LHSFCanada @LHSCCanada @CIHR_ICR

Had a blast presenting our work on mechanisms of resistance to RAF inhibition in lethal thyroid cancers at #AACR24 Stay tuned for more to come 👀

MD PhD student @peteryufanzeng and Post Doc @mushfiqddc presenting our latest work in targeted therapy for anaplastic thyroid cancer and a novel immmunotherapy combination for HNSCC at #AACR24 @AACR @Western_MDPhD @SchulichMedDent @LHSFCanada @CIHR_ICR