Natsuhiko Kumasaka

I'm delighted to present our nationwide effort to identify genetic determinants of child health and development in Japan. medrxiv.org/cgi/content/sh…

CellPhoneDB v5 is officially published! nature.com/articles/s4159… Very happy to have played a small role in it by developing some tools to help visualise the complex cell-cell interaction data!

✍️ Writing is thinking. 👉🏼A powerful editorial in Nature Reviews Bioengineering (Vol. 3, p. 431, 2025) reminds us of something timeless: in science, writing is far more than reporting results. It’s a way of sharpening thought. 👉🏼Even in an age shaped by large-language models,…

💬 Professor Sir Rory Collins, Principal Investigator and CEO, UK Biobank on reaching the 100K Imaging Project milestone 🔽

A pre-trained t-test transformer - nxn.se/p/a-pre-traine…

～ 今年もやります、遺伝統計学・夏の学校 ～ 遺伝統計学の理論~実践のハンズオン演習セミナーです(2025/8/29金-31日)🧬💻🏝️ Hybrid形式(会場:東京大学本郷キャンパス). 是非ご参加ください. #bioinfo #gwas #eqtl #singlecell ※ 初学者向け「基礎編」は今回で一旦終了です genome.m.u-tokyo.ac.jp/school_2025.ht…

祝🎉6月6日は『バイオバンクの日』 日本の14のバイオバンクが参画するバイオバンク・ネットワーク ジャパンは、2025年6月6日に一般社団法人日本記念日協会より認定を受け、6月6日を『バイオバンクの日』として記念日に登録いたしました。 biobank-network.jp/news/3fb5jAWOi…

Interesting GWAS on accumulation of aging-related mitochondrial mutations biorxiv.org/content/10.110…

Check out our scPrediXcan paper cell.com/cell-genomics/… Led by talented @Charles_Zhou12, supervised by @MengjieChen6 and me, with thanks to many contributors scPrediXcan integrates deep learning and single cell expression data into a powerful cell type specific TWAS framework.

JOB: Japan Omics Browser (japan-omics.jp) provides integrative visualization of multi-omics data bmcgenomics.biomedcentral.com/articles/10.11… 🧬🖥️🧪 github.com/ytakahashi-sta…

Excited to share our latest manuscript on "Dual exposure-by-polygenic score interactions highlight disparities across social groups in the proportion needed to benefit" with Greg Gibson (@genomestake), medrxiv.org/content/10.110… [1/9]

Very excited to share our preprint led by @MGLevin @skoyamamd @jakob_woerner & with @damrauer assessing genome-wide pleiotropy of >1,000 clinical traits across ~1.7M individuals with nearly 30K locus-trait associations! medrxiv.org/content/10.110… @medrxivpreprint [1/3]

【🧬4月25日はDNAの日】DNAって何？どうして私たちにとってそんなに大事なの？ 東大公式Xで紹介しているBBJの特集記事で、研究者たちの想いに触れてみてください。DNAクイズにもチャレンジ！ ➡️ biobankjp.org/12035 #DNAの日 #ゲノム医療

🚀 Our perspective is out in @Nature! We present a roadmap for Multimodal Foundation Models (MFMs) — large AI models pretrained across multi-omics and multi-timepoint data — to serve as the computational backbone for building virtual cells. Read the full paper in Nature:…

"Human and bacterial genetic variation shape oral microbiomes and health" medrxiv.org/content/10.110…

📢 new preprint alert: So so excited to share our analysis on the impact of common and rare variants on single-cell gene expression in blood, using WGS and scRNA-seq data from nearly 2,000 individuals and 5.4m cells as part of TenK10K phase 1 🧬medrxiv.org/content/10.110… 🧵👇 (1/n)

New GWAS for Parkinson's disease‼️🧬 👉63,555 cases, 17,700 proxy cases, 1,746,386 controls 👉134 risk loci (59 new) For common diseases, increases in GWAS sample sizes keep offering significant knowledge gains! Post-GWAS analyses also tend to be very informative with (i)…

Thrilled to share that our paper has been accepted to #ESHG2025 as an oral presentation! x.com/natsuhiko83/st…

3/21 (金)「第1回 企業と研究者との交流イベント」（東京大学 大学院新領域創成科学研究科主催）でBBJの松田浩一代表が「個別化医療を目指したバイオバンク・ジャパンの取り組み」というテーマで登壇します。参加登録等の詳細は、以下でご確認ください。biobankjp.org/11308

Neuroscientists are experts at inter-disciplinary collaboration. From novel genetics approaches to imaging and AI, there was no shortage of innovations from these types of partnerships at this year’s neuroscience meeting

DNA sequencing data for over 37,000 children and parents is now available to researchers worldwide 🧬 Collected over multiple decades, these data can be combined with existing health information provided by participating families. Read more ⤵️ sanger.ac.uk/news_item/larg…