Marina Sirota
@msirota84
Bioinformatician, data scientist, researcher
Existing cancer drugs may slow or reverse Alzheimer’s symptoms, a @UCSF/@GladstoneInst study finds. “We're excited that our computational approach led us to a potential combination therapy for Alzheimer's,” UCSF’s Marina Sirota (@msirota84) says. ucsfh.org/4eZIGWZ
How can researchers identify effective drug combinations to treat Alzheimer's disease by targeting different brain cell types simultaneously?@CellCellPress @UCSF_BCHSI "Cell-type-directed network-correcting combination therapy for Alzheimer’s disease" • Alzheimer's disease…
Watch @msirota84 @SirotaLab @UCSF @GladstoneInst on latest @CellCellPress paper!
Researchers from UCSF discovered two FDA-approved cancer drugs appear to slow, or even reverse, memory loss. ktvu.com/video/1678554?…
What an honor to be able to be able to share our work on KTVU this morning: ktvu.com/video/1678554 with my former graduate student Dr. Yaqiao Li! @UCSF_BCHSI @SirotaLab @GladstoneInst
🚨 NEW 🚨 "Cell-type-directed network-correcting combination therapy for Alzheimer’s disease" from the Huang Lab at Gladstone and @msirota84 @UCSF published in @CELL bit.ly/4kW1jMV
Cell-type-directed network-correcting combination therapy for Alzheimer’s disease @CellCellPress @msirota84 cell.com/cell/fulltext/…
A surprising duo: Two FDA-approved cancer drugs—letrozole and irinotecan—show promise in reversing Alzheimer’s symptoms in mice - our study published today in Cell led by Yaqiao Li in collaboration with Yadong Huang @SirotaLab @UCSF_BCHSI @GladstoneInst: sciencedirect.com/science/articl…
Today I celebrated the life of @atulbutte, an incredible person whose absence is felt deeply. I learned so much from him. His lesson on social media: with so much negativity out there, we must lend our voices to share more positivity - its a moral imperative. I will try.
If you were impacted by Atul Butte personally or professionally, we hope you will take a moment to share a memory and photo at kudoboard.com/boards/OMydGod…. These will be shown at the celebration of life this Saturday ⤵️
Dear colleagues and friends, please join to Celebrate the life of Atul Butte on Saturday at 10am. Co-hosted by @ucsf, @Stanford @Harvard

Celebration of the life of Atul Butte. Join colleagues from three universities to celebrate him at 10 am PST on Saturday.
My heart is broken for the loss of my friend and mentor Atul Butte, for his wife Gini, and for all of us who benefited from his giant intellect, smile, friendship, and huge heart (1/2)💔
If you were impacted by Atul Butte personally or professionally, we hope you will take a moment to share a memory, photo, or even just brief comments (2/2) kudoboard.com/boards/OMydGod…
Please join us in Palo Alto this Saturday June 21 @ 10a for a 𝐜𝐞𝐥𝐞𝐛𝐫𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐃𝐫. 𝐀𝐭𝐮𝐥 𝐁𝐮𝐭𝐭𝐞’𝐬 𝐥𝐢𝐟𝐞 co-hosted by UCSF, UC Health, Stanford, and Harvard stanfordmedicine.qualtrics.com/jfe/form/SV_1T…
My heart is broken for the loss of my friend and mentor Atul Butte, for his wife Gini, and for all of us who benefited from his giant intellect, smile, friendship, and huge heart (1/2)💔
With a heavy heart, I share the loss of my mentor, Atul Butte. His brilliance, kindness, and unwavering guidance shaped countless lives, including mine. Atul’s passion for science and mentorship was a gift to the world, leaving a legacy that will inspire forever.💔 #ThankYouAtul
Between alarms and sheltering, I learned last night that my postdoc mentor, Professor Atul Butte @atulbutte, has passed away, and he is only 55 years old. This is devastating news 💔. Atul was a giant in so many ways. He was a visionary leader in translational bioinformatics…
Heartbroken to share that @atulbutte has passed away. He was my mentor, collaborator, and dear friend for nearly 20 years. His brilliance, vision and belief in people changed my life—and so many others. We will carry his legacy forward. @UCSF_BCHSI @UCSF @UCSFPrecision




A privilege for our @UCSF team - Marina Sirota @msirota84, Roberta Keller, Boris Oskotsky @oskotsky, Jean Costello, Jackie Roger - to work with the @Stanford team, led by Joe Phongpreecha & Nima Aghaeepour @NimaAghaeepour, exploring AI-guided TPN formulations for infants
Researchers at Stanford and UCSF aspire to bring AI beyond predictive diagnosis and, instead, use it to guide interventions. The team trained an AI model to create recipes of total parenteral nutrition, a life-saving treatment given to infants. stanforddaily.com/2025/04/18/ai-…
Our OnSIDES db -- the worlds most up-to-date resource of drug side effects is published at @MedCellPress For all your drug safety analysis and prediction needs. OnSIDES is the first resource to combine US, UK, EU, and Japanese data all in one place. cell.com/med/abstract/S…
My team surprised me with a beautiful 'card' and flowers to celebrate my 10 year @UCSF anniversary! What an amazing decade! Thank you so much @SirotaLab!!!!!!


