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Practical resources for today's #clinicians. Timely news and resources across #medical disciplines for today’s #primarycare and #internalmedicine specialists.
Study Update: Setmelanotide in acquired hypothalamic #Obesity. “At 52 weeks, SET‑treated participants demonstrated a mean reduction in #BMI of 16.5% from baseline, compared to a mean increase of 3.3% in BMI in the placebo group.” bit.ly/4kO15HF #ENDO25

Lidocaine Toxicity Alert: Although overall local anesthetic poisonings are declining, #Lidocaine-related deaths in the US. surged nearly 3‑fold in the past decade—highlighting a critical need for heightened clinician awareness. bit.ly/451zVHw @RAPMOnline @mfettiplace
Can #Semaglutide curb alcohol use? GLP-1 agonists like semaglutide may reduce drinking by acting on brain reward pathways — not just weight. More trials needed. bit.ly/4kqr8oJ #AddictionScience #AUD #AlcoholUseDisorder @UNC_SOM @MedUnivSC
🎧 Collegiality isn’t just harmony—it’s life or death. Strong team culture = ↓ burnout, ↓ PTSD, ↓ medical errors. @AHRQNews: Teamwork cuts errors by 50%. bit.ly/40ZjmdR #MedTwitter #Burnout #BeWellPracticeWell @dr_michaelmcgee

Scan both legs for SVT🩸. Duplex US is the gold standard for SVT — & 1 in 4 patients will also have a #DVT needing anticoagulation. 17% find a thrombus in the opposite leg. Long-term #VTE risk stays elevated for years.➜ bit.ly/4kvbW9o #VascularSurgery @AndreaObiMD
Sodium Channel Inhibitors, such as the newly FDA approved non-opioid suzetrigine, have a unique mechanism of action that suppresses pain without making the patient lose all sensation. bit.ly/4eV5qHF #PainMedicine #Neurology #NaV1point8 @UCDavisHealth
ICD‑10‑CM updates coming Oct 1: 487 new codes—including #Xylazine-associated wounds, flank/pelvic pain, #Ophthalmic conditions, & #Glaucoma—to improve diagnostic accuracy & billing specificity. Is your team prepared? bit.ly/4lRZwdf #MedicalCoding @CDCgov @CMSGov
Semaglutide was linked to a lower risk of ADRD vs 7 other diabetes meds in a 3-year study of 1.7M T2D patients. “It is highly effective in treating #Obesity, T2D, & CVD—all key risk factors for #Dementia,” said Rong Xu, PhD. bit.ly/4ksPf5H @TulaneDoctors @CWRUSOM

#ENDO2025: Tirzepatide led to rapid #WeightLoss and a striking boost in testosterone, LH, FSH, & SHBG in obese men with metabolic #Hypogonadism—outpacing both lifestyle & testosterone patch arms. bit.ly/40P2eYg #Endocrinology #MetabolicHealth @TheEndoSociety

Ready to address rising patient interest in blood-based testing? The #Lumipulse pTau217/Aβ42 plasma ratio provides a scalable, minimally invasive method to detect #AmyloidPlaques—enabling earlier, more accessible #Alzheimers diagnoses. bit.ly/3H0NMoW #Biomarkers

Our vulnerability is a strength — we shouldn’t hide who we are in medicine. @KgLeventhal in Ep 13 of Moving Ahead in Medicine. For 18 months, Dr Michelle Lee, MD, has asked: “What have you changed your mind about since med school?” bit.ly/46kmJ2s #MedTwitter #Wellness

FDA-approved: Tirzepatide is now an option for chronic #WeightManagement (BMI ≥30 or ≥27 w/comorbidity). Weekly #SubQ dose, titrated up to 15 mg. SURMOUNT: Up to 21% mean #WeightLoss, plus CV benefits, but watch for GI AEs & rare #Thyroid risks.bit.ly/4lj9rYI #Obesity

Which test can best diagnose pulmonary embolism in a pediatric patient? Pediatric hematologist Hilary Whitworth, MD, MSCE, explains. bit.ly/44IRFHe #Thrombosis #Hematology #Pediatrics #PulmonaryEmbolism @ChildrensPhila

“Endocrinologists are being squeezed by #Medicare cuts, rising costs, & low pay in a high-demand field,” -@DishaKumarMD. Low pay + high demand (only ~8K in the U.S.) = fewer trainees. Read our report, The Evolution of Medical Practice: bit.ly/44nm9j7
💤 New IBD study: Sleep architecture is driven by #Inflammation, not just symptoms. Wearables show active inflammation cuts #REM & boosts light sleep — subjective flares alone don’t. Could sleep tracking flag early flares? ➜ bit.ly/4eKPfNc #IBD #SleepMedicine #Neurology

#ICH Management Update: Rapid BP reduction to <140 mmHg within 6 hrs post‑hemorrhage is safe per ICH‑ADAPT‑2—but avoid excessive fluctuations or AKI risk. Details on how to manage: bit.ly/45ijFmA #Stroke #EmergencyMedicine @American_Stroke @YasminAbdulNZ

Lidocaine Toxicity Alert: Although overall local anesthetic poisonings are declining, #Lidocaine-related deaths in the US. surged nearly 3‑fold in the past decade—highlighting a critical need for heightened clinician awareness. bit.ly/451zVHw @RAPMOnline @mfettiplace
#Endo2025: OPT101 Phase 1b Trial: Reduced inflammatory #Biomarkers (Th40, IFNγ, TNFα) & ↑C‑peptide in longstanding #T1D—signaling preserved β‑cell function. bit.ly/4lIo1sY #Diabetes #Type1Diabetes @TheEndoSociety @dwagT1DCure @DishaKumarMD

New ICD‑10 codes add precision: flank pain gets laterality, #Xylazine ulcers get toxicity+ulcer combo, #TED gets laterality. These changes aren’t just semantics—they affect clinical reporting & reimbursement. Start training now. bit.ly/4lRZwdf #ICD10 @CDCgov @CMSGov

Can semaglutide curb alcohol use? 🧪 GLP-1 agonists like semaglutide may reduce drinking by acting on brain reward pathways — not just weight. More trials needed.bit.ly/4kqr8oJ #AddictionScience #AUD #AlcoholUseDisorder @UNC_SOM @MedUnivSC