Matt Carson
@mccarson23
Organic Chem PhD Candidate @KozlowskiMarisa | @CMU_Chem ‘21 | Total synth and💡methods
Excited to share our total synthesis of aporphine alkaloids! Inspired by biosynthesis, we use a non-natural intermolecular photochemical phenol coupling to access analogues for serotonin & adrenergic receptor profiling. @KozlowskiMarisa @TotalSynthesis pubs.acs.org/doi/10.1021/ac…
Photochem. synthesis of aporphine enables analogs with 5-HT₂ and α₁A receptor activity｜Total Synthesis of Aporphine Alkaloids via Photocatalytic Oxidative Phenol Coupling and Biological Evaluation at the Serotonin 5-HT2 and Adrenergic α1A Receptors pubs.acs.org/doi/10.1021/ac…
New route to aporphine alkaloids via photochemical phenol coupling! Access to analogues enables bioactivity studies at serotonin & adrenergic receptors. #JMedChem @KozlowskiMarisa go.acs.org/cRb
#JACS #Alkaloids #OrganicSynthesis pubs.acs.org/doi/10.1021/ac… Aporphine alkaloids are important natural products with uses ranging from traditional Chinese herbal medicine to modern clinical applications. These compounds are isolated from a variety of plants and possess many ...
Excited to see our work on using partial isotopic labels to obtain Regioselectivity and KIE information without tedious separations out now in @ACSCentSci! Do have a look! pubs.acs.org/doi/10.1021/ac…
We are thrilled to have our work highlighted in Synfacts! @PennChemistry
Thrilled to announce that our latest work is now published in @ACSCatalysis! Super proud of the team and the rest of the @KozlowskiMarisa for their hard work and support! Check it out! pubs.acs.org/doi/10.1021/ac…
Out today in @ChemRxiv, we present a new approach towards simplifying regioisomer identification by using partial isotopic labelling. Glad I could be part of this project in the @KozlowskiMarisa group and congratulations to everyone involved. chemrxiv.org/engage/chemrxi…
Congrats to Matt, Cindy, and Yaning on their work out now in @ACSCatalysis!
Thrilled to announce that our latest work is now published in @ACSCatalysis! Super proud of the team and the rest of the @KozlowskiMarisa for their hard work and support! Check it out! pubs.acs.org/doi/10.1021/ac…
Thrilled to announce that our latest work is now published in @ACSCatalysis! Super proud of the team and the rest of the @KozlowskiMarisa for their hard work and support! Check it out! pubs.acs.org/doi/10.1021/ac…
Today in @ChemRxiv, we utilize catalytic pyridinium additives alongside an Ir photocatalyst to facilitate photochemical amination of phenols and halophenols. Many thanks to Cindy and @ynliu217 for all their help!🎉 @KozlowskiMarisa @PennChemistry chemrxiv.org/engage/chemrxi…
A bright idea: . . . Photochemistry in Pharmaceutical Development: A Survey of Strategies and Approaches to Industry-wide Implementation. Learn from the IQ Continuous Manufacturing Drug Substance working group pubs.acs.org/doi/10.1021/ac…
Check out this review in our latest issue by @mccarson23 & Marisa C. Kozlowski @KozlowskiMarisa @PennChemistry on the recent advances in oxidative phenol coupling for the total synthesis of natural products Read the full article on our website🔽 pubs.rsc.org/en/content/art…
Excited to finally share the next story of my PhD! We explored the photocatalytic coupling of phenols and pyridines to make a new class of pyridinium salts! @KozlowskiMarisa @PennChemistry @JOC_OL pubs.acs.org/doi/10.1021/ac…
