Matthew Lungren MD MPH
@mattlungrenMD
Chief Scientific Officer @Microsoft Health & Life Sciences + Adjunct Professor @Stanford || Prev: @StanfordMed @Dukehealth
Excited for MedHELM to be out! This is an open-source clinician-validated framework built to evaluate medical AI on real-world tasks, offering a more meaningful alternative to traditional exam benchmarks and helping the community build safer, more reliable models for medical…
🧵 🩺 LLMs score ~99% on medical licensing exams, but are they ready for real medical deployment? Our new research reveals major gaps between test performance and clinical readiness. Introducing MedHELM: Holistic Evaluation of Large Language Models for Medical Applications👇
Featuring @wguyman @hoifungpoon & read our blog on the Healthcare Agent Orchestrator here: aka.ms/HLSatBuild25
If you want to hear the ‘story behind the story’ of our work driving innovation to impact at scale and empowering the healthcare ecosystem with the industry’s best AI models and capabilities (we are always shipping!) it all starts with cross-org collaboration!
AI is driving real-world transformation in healthcare. Learn how Microsoft works to empower developers and clinicians around the globe with dynamic new tools, including healthcare-focused agents that can collaborate—with each other and with people: msft.it/6018SdZi0
Thank you @shreydiwjain for your leadership driving the @Stanford collaboration forward and helping to make this transformative announcement possible!
I'm happy to announce the launch of the Healthcare Agent Orchestrator, a project I led at Microsoft with an incredible team! Watch @satyanadella's keynote presentation highlight our incredible collaboration with @StanfordHealth.
Harnessing AI to help with difficult cancer decision problems: A pleasure to join @shreydiwjain for a fireside conversation on pathways forward for translating AI advances into tangible tools for enhancing clinical care @MSFTResearch @mattlungrenMD @Microsoft @StanfordHealth
Had a great conversation with @erichorvitz, Microsoft’s Chief Scientific Officer, on how AI is transforming cancer care. We explored how AI can enhance tumor boards and bring more personalized, data-driven care to patients -now made possible through Microsoft’s Healthcare Agent…
Recent podcasts for those curious about Microsoft’s approach to Healthcare AI: 1) From Research to Clinical Impact @mattlungrenMD , Jonathan Carlson, Smitha Saligrama, Cameron Runde (Statton) and I discuss translating the latest technology from research to healthcare. 2) AI…
Chris Bishop, Technical Fellow and Director of Microsoft Research AI for Science, explains how Microsoft researchers recently achieved a milestone in solving a grand challenge that has hampered scientists and slowed innovation for decades. Watch the video: msft.it/6019SQtUX
Celebration of the life of Atul Butte. Join colleagues from three universities to celebrate him at 10 am PST on Saturday.
𝐀𝐈 𝐍𝐞𝐰𝐬: @mattlungrenMD, @Microsoft's Chief Scientific Officer for Health and Life Sciences, shares his take on how AI is changing healthcare today and what is possible in the future. Full video: biotechtv.com/post/microsoft…
Less than 1% of the 20 million people diagnosed with cancer every year receive care from top-tier multidisciplinary teams (known as ‘tumor boards’), where specialists collaboratively analyze extensive patient data to design personalized treatment plans. And cancer care is just…
We’re making it easy for developers to build and deploy healthcare agents, especially for complex cancer care scenarios like tumor boards. This demo shows how to: 1. Deploy and fine-tune health AI imaging models 2. Customize agents using health AI models as tools 3.…
Examples of interacting with the Healthcare Agent Orchestrator in Microsoft Teams 1/ Orchestrator Agent Builds a plan from the user query, choosing which agents to run and in what order. The user can edit the plan. All queries route through the orchestrator, which decides which…
AI is driving real-world transformation in healthcare. Learn how Microsoft works to empower developers and clinicians around the globe with dynamic new tools, including healthcare-focused agents that can collaborate—with each other and with people: msft.it/6018SdZi0
Stanford Medicine is orchestrating multiple agents to connect medical data, clinical trials, and more - all with the goal of delivering more effective cancer care. Incredible to see in action.
We have seen many ways that generative AI can transform healthcare but over-stretched health-IT teams can’t deploy new software systems to surface the latest advancements fast enough. But... what if developers could meet clinicians where they already work today, building,…

Radiologists, what if your AI could draft prelims like a seasoned fellow – especially for all those incidental findings? 🤯 Super excited to announce a2z Instant Prelims from @a2zradiologyai! a2zradiology.ai/product/introd…
A big day – we are making the largest dataset of chest X-rays available to the world. This is the first dataset to cross 100k patients. huggingface.co/datasets/rajpu…
What a special day! After an amazing 50 years, marked by some very special moments for me (Windows 95, Internet Explorer, Xbox, Bing & Surface!), we’re looking ahead to the future and this incredible era of AI. Today we take the next step to make Copilot truly Your AI Companion.…
We are hiring a Postdoctoral Fellow! Work with @UCSFimaging's Dr. Rajesh Shah on AI-driven radiologic image analysis, LLM applications in health records & multimodal data integration. Ideal for PhDs in CS or related fields with experience in AI, imaging & data analysis. ⬇️