The Matile Group
@matile_group
Supramolecular Systems (th)at Work
This Swiss-ERC Advanced Grant will last until 2027, with about 1-3 postdoc, PhD openings per year, beginning 2023: Organic synthesis, chemical biology, supramolecular chemistry, catalysis, fluorescent probes, and cascade exchange chemistry to decode cellular uptake networks.
A big thank you to all who made this possible! 🙏 An ERC grant without timesheets sounds really cool, PhD students, postdocs, please apply, starts November 1, 2022 @UNIGEnews @sciences_UNIGE @UniGe_OrgChem @NCCR_ChemBio @NCCR_MSE
Thank you so much for a wonderful, inspiring day in Freiburg!
The beauty of disulfide exchange and fluorescent flippers - great chemistry of Stefan Matile @matile_group at @livMatS_UniFR @UniFreiburg @FreiburgChem @JessenLab @DumeleLab @pappas_babis @WerzLab
Electric-Field Catalysis on #CarbonNanotubes in Electromicrofluidic Reactors: Monoterpene Cyclizations (Stefan Matile and co-workers) @unige_en @matile_group #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
An update on dynamic covalent cascade exchange chemistry, thiol-mediated uptake and the Swiss-ERC TIMEUP project, now in Chimia, the POA Journal of the Swiss Chemical Society chimia.ch/chimia/article… @CHIMIA_journal
The 4th Switzerland-Japan Biomolecular Chemistry Symposium (Kyoto) was a great opportunity to have some very flutiful scientific discussions and it was a lot of fun ‼ I also made some new friends of Switzerland!
Oh, what a privileged scaffold, asparagusic acid, here as the chiaroscuro @JACS_Au cherry on the cake in Geneva pâtisserie, tiny but full of positive surprises: pubs.acs.org/doi/10.1021/ja… The new Golgi trackers are already available @spirochrome
According to theory and biology, the control of electron displacements during a reaction with electric fields could change the way we make molecules. In our new paper in @angew_chem, we examine our approach to do this with monoterpene cyclizations onlinelibrary.wiley.com/doi/10.1002/an…
📢New SPY-Golgi probes! We are thrilled to introduce two innovative probes for live-cell imaging of the Golgi apparatus: SPY650-Golgi and SPY555-Golgi. spirochrome.com/products/?_cat… These probes label the Golgi apparatus in live cells within minutes and remain stable through…
Stand-up thumb push lions, the Goldilocks inverted region and sigma acidity in pnictogen-bonding transport and catalysis: More is not always better, now new in the flagship journal of the Chinese Chemical Society, DOA – thank you @CCSChemistry chinesechemsoc.org/doi/10.31635/c…
🎉🍾10 YEARS - NEW WEBSITE! 🎂 Join us in celebrating Spirochrome's 10th anniversary and visit our new website! spirochrome.com 10 years ago, the freshly founded Spirochome started commercializing its first two products, SiR-actin and SiR-tubulin! Today, with about 40…
We're excited to share our perspective in @ChemicalScience on the transport of anions across membranes by synthetic anion receptors based on sigma-hole interactions. We're looking forward to seeing further studies on cells and applications in biology! pubs.rsc.org/en/Content/Art…
Pnictogen-Bonding Enzymes (Stefan Matile and co-workers) @matile_group @WardGroupBS @tonifrontera3 @NCCR_MSE #openaccess onlinelibrary.wiley.com/doi/10.1002/an…
The deadline for poster presentation submissions has been extended to September 17th. Don't miss this opportunity to discuss your work with colleagues at the exciting SJBCS2024! Submit your poster abstract here: sjbcs2024.symposium-hp.jp/index.html
📢 The 4th Switzerland-Japan Biomolecular Chemistry Symposium (SJBCS2024), organized by Eiji Nakata @IAE_KU, will be held on Nov. 7–8 at Kyoto University Uji Campus. Official HP is now open. Check out the fantastic line-up of invited speakers and join us! sjbcs2024.symposium-hp.jp/index.html
All what you wanted to know about using flipper probes @spirochrome @matile_group for cell biology and didn’t dare asking is in: rdcu.be/dSmET Thanks to all co-authors and colleagues, thanks to @CRoffay & @vincent81196538 for their great work!
Thank you very much for this highlight of our paper in ChemistryEurope, the new GOA journal of the European Chemical Societies …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ce… @ThornSesholdLab @ChemistryEur @UNIGEnews @Ch_Bioch_UNIGE @sciences_UNIGE @UniGe_OrgChem @snsf_ch @NCCR_MSE @ChemEurope
Unique Patterns of Thiol-Mediated Cellular Uptake: Two existing exchange networks and a new repressor pathway discovered, improving the understanding of cellular delivery systems and offering new strategies for drug delivery chemistryviews.org/unique-pattern…
Thank you very much for these beautiful images!
Want a non genetically-encoded probe to label the Golgi in imaging and #STED super resolution experiments? Check out the clever trick from the @matile_group! Happy to have been able to contribute to this pubs.acs.org/doi/10.1021/ja…
Asparagusic acid: Dynamer materials, cellular uptake, and now Golgi trackers, doubly palmitoylated, from disulfide to thioester exchange cascades, for super-resolution, flippers and more - what a privileged scaffold! Now new in @JACS_Au pubs.acs.org/doi/10.1021/ja…
Demonstrating super-resolution imaging and single-molecule detection with flippers in the latest paper of the Fürstenberg lab in collaboration with the Matile group @afuerstenberg @matile_group pubs.acs.org/doi/full/10.10…
The whole Flipper-TR family of mechanosensitive probe goes #SMLM & PAINT thanks to Jimmy Maillard, Ewa Grassin, @pricelesska and colleagues in a joint effort from @matile_group and Alex Fürstenberg labs in @sciences_UNIGE. Congrats! doi.org/10.1021/acs.jp…