Dr. Manoj Jangra
@manojjangra91
Applied microbiologist. Postdoctoral Fellow @McMaster University
🚨 New preprint! Read about Manikomycin, a novel cyclic depsipeptide from S. rimosus that kills MDR bacteria by targeting the E site of the bacterial ribosome — a first! 🧬✨ Link: researchsquare.com/article/rs-692… #CryoEM #Antibiotics #DrugDiscovery
It’s Friday. A new episode is now available. Tune in to learn about lariocidin: a potential antibiotic. Link in comments. #microbiology #podcast #stem
New online! Lassoing bacterial ribosomes nature.com/articles/s4157…
'We constantly need new drugs': Discovery in Hamilton backyard could lead to new antibiotics thespec.com/news/hamilton-… via @thespec
Digging in the dirt: Scientists discover a new antibiotic compound from an old source An antibiotic peptide named lariocidin—named for its knotted, lasso-like chemical structure—has a unique mechanism of action cidrap.umn.edu/antimicrobial-… Photo courtesy of McMaster University
A very enthusiastic and optimistic writer 😊 New Antibiotic Discovered in Technician’s Garden Kills Drug-Resistant Bacteria livequrious.com/new-antibiotic…
New antibiotic that kills drug-resistant bacteria--via novel mechanism--discovered in technician’s garden @Nature nature.com/articles/d4158… nature.com/articles/s4158…
Very happy to share that our work on the discovery of new class of Ribosome targeting antibiotic is published in Nature today. A beautiful example of a multi collaborative study. Many thanks to all the people who contributed.
Nature research paper: A broad-spectrum lasso peptide antibiotic targeting the bacterial ribosome go.nature.com/3FJLuu0
📢@CanadainIndia 🇨🇦🇮🇳& @CitImmCanada 🇨🇦 🚨We can no longer tolerate your ignorance ! Our #applications are on hold from a long time.@marcomendicino& @nadirypatel sir,Please clear the #Backlog of work permit files. #SOWP #LMIA WORK PERMIT #PGWP #GSS etc. @NewsroomGC @JustinTrudeau
🚨#🇨🇦IN🇮🇳 & #IRCC🇨🇦! It's a time to make lives easy of #Work Permit Applicants,waiting for long time by #finalizing their applications.Our future is at #stake.Though everyone suffered,We want justice like other who applied after us and got #results.(1/2) #LMIA WP #SOWP #PGWP #GSS
#Canada in India , Finalize old work permit applications of 2020( LMIA BASED, SOWP and LMIA EXEMPT).Putting our applications on hold for long time is unjustified and unacceptable. @CitImmCanada @nadirypatel @JustinTrudeau @marcomendicino
Purification and biological activity of natural variants synthesized by tridecaptin M gene cluster and in vitro… disq.us/t/3kbd8uu
The full article is now online. An attempt to tackle multidrug-resistance in S. aureus by inhibiting the efflux pumps. "Microbe-Derived Indole Metabolite Demonstrates Potent Multidrug Efflux Pump Inhibition in Staphylococcus aureus" frontiersin.org/article/10.338…
Microbe-derived Indole Metabolite Demonstrates Potent Multidrug Efflux Pump Inhibition in Staphylococcus aureus frontiersin.org/article/10.338…
IMTECH’s novel compound treats colistin-resistant bacteria thehindu.com/sci-tech/scien…