Musculoskeletal Aging and Metabolism Laboratory

New work from our lab that extends our interest in how metformin, a proposed geroprotective drug, attenuates adaptations to exercise. shorturl.at/9uL5t

Research Specialist - Biology of Aging - Madison, Wisconsin, United States. jobs.wisc.edu/jobs/research-…

Identification of a resistance-exercise-specific signalling pathway that drives skeletal muscle growth go.nature.com/3GZ2ltq

🐭@celliehausen et al (@SzczepanOlszew1 @dmmint10 @maml_UWMadison) #PoWeR elicits #intracellularsignaling, #mitochondrialadaptations, and #hypertrophy in multiple #muscles consistent with #endurance and #resistance exercise training ow.ly/tOUQ50VAir2

Rapamycin does not compromise physical performance or muscle hypertrophy after PoWeR while intermittent rapamycin alleviates glucose disruptions by frequent rapamycin biorxiv.org/content/10.110…

biorxiv.org/content/10.110…

Inhibition of mTORC1 by rapamycin results in feedback activation of Akt S473 and aggravates hallmarks of osteoarthritis in female mice and non-human primates Dennis Minton, @LammingLab, Adam Salmon, Adam Konopka (@maml_UWMadison) and co-authors. biorxiv.org/content/10.110… #…

Registration Now Open! Join us for the 53rd Annual Meeting of the American Aging Association in Anchorage, AK at the Dena'ina Center, May 11-14, 2025! Register today and be part of the conversation! americanagingassociation.org

Our Clinical ‘Crayon’ team in between biopsy and dosing visits for our ongoing #rapamycin clinical trials. Happy Halloween!

Guess what? Diet and exercise preserve aging muscle function. In our morning session, talks from Betinna Mittendorfer, Adam Konopka and Chris Adams discussed mechanisms, outcomes and potential interventions for healthy aging.

APS member Adam Konopka is quoted in "Anti-Aging Enthusiasts Are Taking a Pill to Extend Their Lives. Will It Work?" from the @nytimes: ow.ly/qwj750TvEBA #ISpyPhysiology CC: @maml_UWMadison

🚨🚨Registration closes September 6th! Space is limited, don't miss out!

Glad our leadership understands the value of healthy lifespan for Wisconsin and beyond! #geroscience #healthspan #aging

Really happy to see this paper finally out in the world! Satellite cell-derived TRIM28 is pivotal for mechanical load- and injury-induced myogenesis | EMBO reports embopress.org/doi/full/10.10…

Madison has been ranked the 5th fittest city in America, in the American College of Sports Medicine's American Fitness Index. channel3000.com/features/madis…

Took 1-8y off science for family during your postdoc or faculty position? Contact an NIH-funded lab to see if they will write a reentry with you. Please RT these little-known supplements: nigms.nih.gov/Research/Mecha…

📢Register now for the 2024 Masoro-Barshop Conference on Aging, taking place Oct 10-13 at the Mayan Dude Ranch in Bandera, TX. "Targeting #MetabolicFunction to Improve #Aging and #Healthspan." More info here: bit.ly/3UG2bew

The VitaDAO Aging Science Podcast EP 18 is LIVE! Join us for an insightful discussion with Prof. Adam Salmon on: • Rapamycin • AMPK Pathway • Caloric Restriction Mimetics • Multistress Resistance • Marmoset Study on Rapamycin and more👇 vitadao.com/blog-article/t…

Dr. Nathan LeBrasseur from Mayo Clinic speaking tonight @uwsmph on targeting senescent cells for healthy aging at the @wiscobrien symposium on aging in the lower urinary tract. More presentations tomorrow; virtual option available. View program here: cairibu.urology.wisc.edu/event/uw-madis…