Rosenzweig Lab
@lab_rosenzweig
We use advanced NMR, biophysical, and biochemical approaches to study the structure, dynamics, and interactions of molecular chaperones. Ran by group members.
In a new study, @lab_rosenzweig researchers have uncovered a mechanism by which chaperones protect a protein with a cancerous mutation. Their findings, published in Molecular @CellPressNews, could lead to development of new, targeted cancer treatments >> bit.ly/pin-cancer-Eng
Instead of a regular group meeting, and in light of the current situation here in Israel, we volunteered today helping the local agriculture. We picked, cleaned and packed garlic!


Congratulations to three new Masters from our lab! Mazal tov!

Past & present members of the lab @ICMRBS #ICMRBS2024 Lots of good results here!
Way to go Rina for receiving the Founder's medal in the @ICMRBS! Proud to be part of the lab!

Some of our lab representatives at the Israel Society of Biochemistry and Molecular Biology 🤩


Happy to share our DNNs to transform crowded methyl HSQC spectra of large proteins into spectra akin to Methyl-TROSY is out in @NatureComms Scripts & weights available on GitHub / Zenodo. #NMRChat @gogulan_k @bhu_vaibhav @UCLLifeSciences @TheCrick rdcu.be/dKJGq
Looking forward to Yuval's talk today at the magnetic resonance symposium celebrating Simon Vega!

We are very excited with the release of our latest paper lead by @ZoltzG about a new and unique chaperoning mechanism found in class A JDPs, and its connection to oncogenic p53 mutants. It was great to work again with @BukauLab and Anne Wentink! cell.com/molecular-cell…
A wonderful start to a new year - congratulations Roni, it was a great master's defense, you are officially a PhD student now!


Check out the new paper by @LEK_Lab! Congratulations!
Newest paper from the lab is now out in @PNASNews! Alex (@MethylTROSY), Reid (@ReidAlderson) & others provide mechanistic insights about the mechanism of Caspase-9 activation on the apoptosome. Check it out here: pnas.org/doi/10.1073/pn…
🥳 Our paper on the interaction between E2 and E3 of ufmylation has been published! In collaboration with @lab_wiener and @lab_rosenzweig Congratulations to @SayanikaIndia and @jvarga92 Take a look 👉 doi.org/10.15252/embr.…
📢 Have a look at our preprint on the E2-E3 interaction of ufmylation which was recently updated on biorxiv! biorxiv.org/content/10.110…
Check out Miri and her poster at the @EMBO Proteostasis workshop! 🤩

A bit of good (scientific) news: our paper about disease related mutations in DNAJB6 is out! 🥳 Congratulations to Meital and Dar and thanks to @MeitalOren and Yehuda for a wonderful and fruitful collaboration🪱 nature.com/articles/s4146…
Roni - our representative at the EMBO Susan Lindquist Proteostasis School🤩 @EMBO

Wow. A must-read.
Our #NMRchat DNNs are now able to transform crowded HSQC spectra of large proteins (<350 kDa) into spectra akin to Methyl-TROSY (methyl-TROSY-fication). Read the full story on bioRxiv: doi.org/10.1101/2023.0… @EPSRC #DeepLearning @UCLLifeSciences @gogulan_k @bhu_vaibhav
New year, new group picture. Sweet new year, Shana tova! 🍎 🍏🍯

Well deserved! 🏆
Congratulations to Prof. Lucio Frydman of the Chemical and Biological Physics Department for being awarded the ICS (Israel Chemical Society) Prize for Excellence for his long-standing, seminal contributions to Magnetic Resonance
Interesting and beautiful paper!
Functional regulation of an intrinsically disordered protein via a conformationally excited state: science.org/doi/10.1126/sc…
One of the perks of getting the Blavatnik award is a professional clip of our lab! Check it out! (It's in Hebrew, but there are subtitles): youtu.be/oe1ZsjoOL1E @BlavatnikAwards