Junge_Lab
@junge_harald
Harald Junge's lab studies signaling, development, and disease in the retina and brain. Focus areas include neurovascular interactions and Wnt signaling.
On the cover of Science Signaling! Levey, Abedin, Zhang et al. show that endothelial-specific deletion of MDM2—a key negative regulator of p53—disrupts blood-CNS barrier integrity by regulating Norrin/Frizzled4 signaling. Proud of the team! 🔗 science.org/toc/signaling/…
Faculty Position (open at all ranks) in Retinal Biology and Disease at UMN Twin Cities. z.umn.edu/OVNSResearch UMN job portal Job ID346633
Online today! A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues #retinopathy By SS Sidhu , HJ Junge, @StephAngers & colleagues @UofT @UMNews & AntlerA Therapeutics -> Read #openaccess: embopress.org/doi/full/10.15…
#camostat #camoco19 trial in Aarhus to begin soon. We are mentioned in Science today. sciencemag.org/news/2020/04/t…
#Maskenpflicht (duty to wear a mask) is now trending on Twitter in Germany. We need to learn from the countries that are successfully dealing with the #coronavirus pandemics. They are all in Asia and their population is used to face masks.
We have sent our #SARSCoV2 contructs out to almost 100 labs so far. Currently trying to coordinate with @Addgene for broader distribution, they will be in touch when they can. Let us know if you need SARS-2 plasmids, we are happy to distribute. Please retweet!
Faculty position at the University of Minnesota: retinal biology & disease. Applications must be submitted online at humanresources.umn.edu/content/find-j… Select “External Applicant” and search for 334962 (job ID) and follow the instruction in the job description under How To Apply.
Zhang et al. report human and mouse genetic evidence for a role of Jagged1 in familial exudative vitreoretinopathy, a congenital retinal vascular disease caused by loss of canonical ("wnt"-)signaling induced by norrin. Notch and norrin signaling intertwined? PMID: 31273345
Yang lab and colleagues report that oligodendrocyte precursor cell transplantation in a rodent stroke model alleviates blood-brain brain barrier defects and stroke pathology by increasing levels of Wnt signaling. PMID: 31907363
Postdoc position and Research Scientist positions on cell-cell signaling in blood-brain barrier regulation. Focus will be on novel regulators of Frizzled4 in vascular endothelial cells. Keywords: retina, angiogenesis, vascular biology, ophthalmology. med.umn.edu/ophthalmology/…