Jun Axup Penman
@junaxup
🧠 COO @E11bio, a @Convergent_FROs mapping the brain 🧬 former CSO/Partner @indbio 🎸 science songs http://linktr.ee/mpsci 🧦 DNA socks http://dnasocks.etsy.com
Mapping the off-target effects of every FDA-approved drug in existence (EvE Bio) 6.2k words, 29 minutes reading time owlposting.com/p/mapping-the-… this is a very long essay over @EvEBiotech, a data collection effort that you should know about (it's associated w/ @Convergent_FROs!)
We had a packed room at Night of Neurotech last night! Neuro is getting hotter than ever! 🔥
Neuroscience as a stepping stone to flourishing Almost every psychiatric and neurological condition is rising. It’s an existential threat hiding in plain sight. We need breakthroughs in brain health. Yet I’m increasingly excited about neuroscience expanding (not shifting) from…
Excited to have Victor Holmes join @E11BIO as Chief of Staff! 🎉
This week we’re thrilled to welcome Victor Holmes to the E11 team as our new Chief of Staff! Victor brings 20+ years of experience at Amyris, a leader in synthetic biology. We're excited to benefit from his deep experience in scientific operations, project strategy, and team…
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…
1/4 🚀 Announcing the 2025 Protein Engineering Tournament. This year’s challenge: design PETase enzymes, which degrade the type of plastic in bottles. Can AI-guided protein design help solve the climate crisis? Let’s find out! ⬇️ #AIforBiology #ClimateTech #ProteinEngineering…
🧵1/ LBF7 Spain is happening and we're doing something kinda wild: -We’re gathering the smartest people who want to SOLVE AGING -going to a longevity resort in the Spanish mountains -to learn, discuss and ACTUALLY BUILD stuff for 7 days straight Here’s what we’re cooking 👇
Focused Research Organizations and @Convergent_FROs on @ashleevance's Core Memory! With @AdamMarblestone @AGamick
This week on the Core Memory pod we fix American Science and advance civilization My chat with the founders of @Convergent_FROs corememory.com/p/fixing-ameri…
Super comprehensive guide to fundraising for science orgs - from startups to FROs. Great job @AndreaCoravos!
Most advice on fundraising comes from VCs, and is written for software companies. We’ve published one that’s a little different. By @andreacoravos & Rachel Katz, who have successfully fundraised for and exited their own companies, here’s a guide for founders in healthcare and…
Join us next Tuesday for Night of Neurotech during SF Deep Tech Week! Fantastic speaker lineup: 1. Ying-Hui Fu, Professor of Neurology at UCSF 2. @nathaliegou, CEO of @neurode_labs 3. @LauraDeming, CEO of @cradle_health 4. @rahulchhabra07, CEO of stealth BCI co 5.…
"Robotics" city proposed for Alameda! Glad that @e11bio set up shop here 3 years ago.
1/18 Introducing Frontier Valley: A new special regulation district in SV that’s larger than SoMa. Once approved, it will be America's epicenter for physical AI and deep tech innovation, and will also be a template for "robotics-first" cities that can be replicated nationwide.
New RFP! We give out $5M in grants annually to reduce existential risks from advanced AI. Now we are seeking projects across 39 research areas within security, coordination, research automation, and neurotech. More about the specific work we are interested in funding, and why:…
A new model for science philanthropy - focused thesis-driven funds!
📢 We just released our complete playbook for thesis-driven philanthropic funds. A new model that's creating better outcomes for donors, scientists, and society. Here's how it works: 👇
People often ask how FROs started. Here's the origin story! Honored to be a part of this movement!
MIT News featured the origin story of Focused Research Organizations and @E11BIO coming out of @eboyden3's lab with @AdamMarblestone @SGRodriques @Andrew_C_Payne @tkalil2050 news.mit.edu/2025/former-mi…
Congrats @alexsaraki! We need better animal models especially for studying women's health, reproduction, and longevity!
After over a year of incubating, I’m excited to share a new project inspired by a ~decade of in vivo drug discovery experience 🧬 Artemis is a Focused Research Organization (FRO) to establish alternative, naturally physiologically human-like animal species for complex disease…
Excited to co-host Night of Neurotech at SF Deep Tech Week again with @PsymedVentures! Come hear some amazing work for human augmentation! June 24th lu.ma/night-of-neuro…
We’re co-hosting Night of Neurotech at SF Deep Tech Week with @E11BIO! This year we're featuring founders & scientists exploring far-future neuroscience tech for human augmentation. Neuroscience isn't just for healing; it will elevate everyone's lives. June 24th, 5-8pm Sign up:…
We launched our first open-source software package! 🔬🖥️🌈
E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets! Built on top of Daisy (a lightweight framework from the Funke Lab at Janelia), Volara features block-wise task abstractions, making scalable image…