Joost Snijder

‘Minder management, meer deskundigheid' Zomercolumn in @FD_Nieuws fd.nl/opinie/1563232… (gratis te lezen)

Excited to share that our book chapter on #cryoEM epitope mapping, co‑written with my favourite collaborator @DanielHurdiss, is now out! 🔬 It captures learnings from many biologics projects & we hope it’s a useful resource for structural immunologists! link.springer.com/protocol/10.10…

Microfluidics combined with electron microscopy for rapid and high-throughput mapping of antibody–viral glycoprotein complexes nature.com/articles/s4155…

New online! Finding the lock to fit the key: Ebola virus entry nature.com/articles/s4157…

New online! The HIV-1 envelope glycoprotein: structure, function and interactions with neutralizing antibodies nature.com/articles/s4157…

When particles have orientation bias, the resulting maps are often streaked along the missing directions. In this case study, we cover why orientation bias produces anisotropic #cryoEM maps and how you may be able to recover from it! guide.cryosparc.com/processing-dat…

We sequenced the anti-RSV-F antibody 131-2a by mass spec and determined its epitope by cryoEM. New insights in postF specific binding and antigenic site I. Now published in @ACSPublications Infectious Diseases pubs.acs.org/doi/10.1021/ac… @Weiweipeng1992 @HaanXander @HangryHobbit

✧ Hello Users of Europe! See you next week at the 𝘋𝘈𝘒 𝗘𝗨𝗥𝗢𝗧𝗢𝗨𝗥 2025. Dates added in Germany! Can’t wait to see you ✧ linktr.ee/descartesakant 🇳🇱 🇸🇮 🇭🇷 🇸🇰 🇭🇺 🇩🇪 🇩🇰 🇸🇪

Full article: Identification of β4GALNT2 as an anti-hPIV3 factor through genome-wide CRISPR/Cas9 library screening. Nice work by former PhD student ⁦@XueshengWu⁩. Many thanks to our collaborators! tandfonline.com/doi/10.1080/22…

Very happy that our paper on the receptor binding properties of contemporary H3N2 viruses is now published @CellReports #glycotime cell.com/cell-reports/f…

nieuwe BOOS, over oud LPF-staatssecretaris en notoire huisjesmelker Cees van Leeuwen. huurders werden geïntimideerd en kregen nog tienduizenden euro's; wij gingen er om vragen. en van Leeuwen? die bleek zich maar slecht te kunnen beheersen. bit.ly/boos-CeesvanLe…

Interested in our recent norovirus NS3 work? 👇 Join us to dig deeper! I'm recruiting a PhD candidate to investigate NS3's role in viral replication and assembly using #cryoEM, #cryoET, and other complementary techniques. 🔗 tinyurl.com/4f3t3aae Please share! 🙏

Met de pet rond: deze bewoners betaalden zelf de woningen waarmee ze jongeren konden behouden nrc.nl/nieuws/2025/07…

DS90 targets a highly conserved epitope on the fusion (F) glycoprotein of Nipah virus, blocking its activity at nanomolar levels. Using #cryoEM @CMMUQ1 we mapped the binding site and mechanism, revealing a novel pocket of vulnerability.

And now published! #glycotime "Sialic Acid-Containing Glycolipids Extend the Receptor Repertoire of Enterovirus-D68" fantastic collaboration with @LisaBauerVirus @DebbyvanRiel @TheBoonsGroup enjoy 👍pubs.acs.org/doi/10.1021/ac…

🚨 New paper in @ScienceMagazine! 🚨 We built a safe, atomic-resolution version of Powassan virus, a deadly tick-borne flavivirus with no vaccine or treatment. ✅ First structure ever ✅ BSL-2 safe ✅ Vaccine & antiviral potential Let me show you🧵(1/5) science.org/doi/10.1126/sc…

This is the first-ever structure of Powassan virus. It’s basic science, but it opens the door to safer virus research, new vaccines, and antiviral strategies. Proud to call this the first chapter of my PhD. (4/5) #CryoEM #ScienceAdvances #Flavivirus #virology

Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics. Nature (2025). nature.com/articles/s4158…

‘Potentieel baanbrekende’ uitspraak nabij: is een duur medicijn een schending van mensenrechten? nrc.nl/nieuws/2025/07…

Studying protein-protein interactions at scale with pooled AlphaFold3! biorxiv.org/content/10.110…