Jay Giri

Thread/ New @AHAScience Scientific Statement published online in @CircAHA regarding Interventional Therapies for Acute PE: ahajournals.org/doi/10.1161/CI… Presented simultaneously at @PERTConsortium PE symposium. Summary in this thread.

Looking forward to a new position as Director of Interventional Cardiology at Mass General Brigham. With incredible colleagues throughout the system, we will build the most comprehensive IC program internationally.

Congratulations to the investigators on full enrollment of this landmark trial! And thanks to the patients who participated & @bostonsci for sponsoring this vital study HI-PEITHO is the 1st int-risk PE interventional mega-trial to conclude with PE TRACT & PEERLESS 2 to follow

We’re done. Many thanks to the investigators and patients of the HI-PEITHO trial of ultrasound-assisted catheter lysis+LMWH vs LMWH alone. To randomise 544 patients with PE in a trial such as this, with patients having two or more of HR>100/SBP<110/Sats<90 or RR>20, is a major…

We live in a world of endless quality metrics. Adding another makes no sense. This metric doesn't even meet the definition of a performance measure.

The Linnemeier Award is given each year to an outstanding, early career IC and has been springboard for many leaders in our field including @PhilGenereuxMD, @rwyeh, @DFCapodanno, @jaygirimd, @barbanti_marco, @PhilippLurz. @SimoneBiscaglia. Don't miss your chance to apply!

If you’ve got a little time on your hands, I’d love to challenge your faith in the “doctor shortage.” Thanks to @leah_pierson for the invitation to chat on Bio(un)ethical.

An absolute risk generalizable risk calculator is challenging. Led by @somijemmacho, evaluating AHA PREVENT across 4 academic health systems, we found similar discrimination but variable calibration. A universal absolute risk threshold may not suitably guide.…

Transcatheter Aortic Valve Replacement With Intra-Annular Self-Expanding or Balloon-Expandable Valves: The Multicenter International NAVULTRA Registry: @JACCJournals 🥸 S3 vs Navi: head to head *non randomized* comparison. Of course S3 wins (except for gradients)! 😱Summary

Check out my latest article: Transcatheter Aortic Valve Replacement: Comparing Intra-Annular Self-Expanding and Balloon-Expandable Valves—Insights from the NAVULTRA Registry linkedin.com/pulse/transcat… via @LinkedIn

Mitochondrial dysfunction is increasingly recognized as a central feature in the pathogenesis of a wide array of diseases. However, its role is often oversimplified. While mitochondrial impairment is commonly cited as a root cause in diseases like cancer, type 2 diabetes,…

Renal denervation for HTN was approved the FDA over 18 months ago. But very few cases performed in the US despite a theoretical eligible population >100M patients for this therapy. We cover the elephant in the room: reimbursement in @cardiacinterv. citoday.com/articles/2025-…

Our study on radial artery PCI use in the US, out in European Heart Journal - Radial PCI now over 60% of all PCI - Significant provider variation remains - In IV analysis, radial reduced death and major bleeding, w small Increase in stroke @SmithBIDMC tinyurl.com/vy3f83ek

1/14) I’m thrilled to announce I’ve accepted the position of Structural Fellowship Director at UAB! Honored to lead this prestigious program & advance our mission in structural heart disease.#UAB #StructuralHeart @MustafaAhmedMD @MarkLaw80307275 @BaranAksutMD @DocEBROhimi

Are you under 40 & pushing interventional cardiology forward through excellent clinical care and investigation? Apply for the @crfheart 2025 Linnemeier Award! Join last years’ winners, @RobertAvramMD & @PennCardiology star Alex Fanaroff, & be recognized as young leader in IC.

Cardiovascular trial interventions found to be beneficial among even the frailest of patients, highlighting the need for purposeful inclusion of these patients, who are often excluded from RCTs. Read @AngelaSKoh1 , @DocStrom et al in @JACCJournals : bit.ly/46mFCSs

Congratulations to ⁦@PennMedicine Prof ⁩ @kiranmusunuru⁩ who received the Barry J. Gertz endowed Chair for Translational Research from Dean Jonathan Epstein yesterday!

Important finding on CT and fluoro showing 2nd TAV in Redo #TAVR were 100% underexpanded despite procedural optimization with pre and post dilatation. Time to rethink lifetime management strategy and consider #TAVR explant in low risk pts to avoid redo TAVR PPM ? @JACCJournals…

This is a travesty and a nightmare. The US was a founder of @Gavi. It lowers vaccine costs for the world, has vaccinated 1B children, and averted 19M deaths. This pull out will cost 100s of thousands of children's lives a year -- and RFK Jr will be personally responsible.

I’m usually awkward about award ceremonies – worthy accomplishments are seldom about individual effort. But this one warmed my heart. A celebration of folks who have dedicated decades of their lives to an organization that has truly shaped our the world @American_Heart 1/

Our new PROSPECT II study in Circulation comparing untreated non-obstructive lsns in STEMI & NSTEMI. ~4 such lsns per pt. 2-feature high-risk plaques were equally present (in 38.8% vs. 32.7%; P=0.11). 4-yr rates of untreated lesion-related MACE were also similar (8.6% vs 7.8%).