Dr. Jason Vassy
@jasonvassy
Primary care physician and genomic medicine researcher @VABostonHC | Assoc Prof @HarvardMed | @BrighamWomens | @Genomes2People
Get a taste of the ASHG community before fall! Join us for the virtual Spring Symposium on Cancer Genetics Symposium on April 8-9! It’s a great way to connect before the meeting in Boston, plus you can earn up to 6 CME credits. Register now: learning.ashg.org/p/2025-spring-… #ASHG
Can a clinical polygenic model improve prostate cancer screening? We now describe our P-CARE model and its application in the new ProGRESS clinical trial: From a genomic risk model to clinical trial implementation in a learning health system: medrxiv.org/content/10.110…

I’m excited to bring @DeptVetAffairs and @VeteransHealth to this network of other genomics-enabled learning health systems! We will promote the uptake of evidence-based genomic medicine in patient care. genome.gov/news/news-rele…
Health-literate care organizations use system-wide approaches to help all patients understand and engage in their own care. @marlaclayman, Maren Scheuner, and I propose applying these ideas to precision health. authors.elsevier.com/a/1jYnu3vlFV4E…
What is a health-literate health care organization and how can this be applied to precision healthcare to achieve #HealthEquity? bit.ly/3WIwFOb #PrecisionMedicine
Excited to have brought MCED testing to Veterans at VA Boston!
Galleri is a new type of cancer screening that can detected 50+ different types of cancer with a simple blood draw. Veterans seen at VABHS are eligible for Galleri testing as part of The REFLECTION Study. Contact [email protected] or 617-777-9441 to learn more.
Join us today at 12pm ET!
THIS WEDNESDAY, our live web event will dive into four real-world solutions: ➡️Hub-and-spoke ➡️Train-the-PCP ➡️PCP extender ➡️Specialty integration models Learn how to implement these strategies in your practice as a #GeneticsSpecialist; register now: learning.ashg.org/products/novel…
Today at 12pm ET: Join me and stellar colleagues as we discuss the role of primary care in expanding access to genetics services. "Novel delivery models to meet the demand for genetics services in primary care" @GeneticsSociety learning.ashg.org/products/novel…
Excited to be going “home” to @WUSTLmed this morning to speak about #PGx research and clinical care in the @VeteransHealth Administration.

Fascinating use of cancer PRS for causal estimation of the cost-effectiveness of preventive interventions.
New paper: estimating long-term intervention cost-effectiveness in the absence of data from RCTs and without recourse to Markov models or similar. Methods demonstrated with repurposed use of SGLT2 inhibitors to reduce risk of incident prostate cancer journals.sagepub.com/doi/10.1177/02…
It’s great to share the impressive PCP-genetics e-consult initiative Ben Kerman has led at @BrighamWomens for the last 5 years.
Can an electronic consultation service led by a "primary care physician champion" triage and respond to genetics questions? The answer is yes, and it yields high provider satisfaction bit.ly/3J8Jfyt @jasonvassy #GIMO #ReferralAndConsultation #Genetics #PrimaryHealthcare
VA healthcare now expanding to an unprecedented number of Veterans! @VeteransHealth
A message from an older gentleman.
Testing ALL women aged 30 to 35 years for BRCA1, BRCA2, and PALB2 was cost-effective in this modeling study, compared with family history-based approach jamanetwork.com/journals/jaman…
Congrats to the eMERGE team! Detailed look at a PRS implementation pipeline, including a discussion of the diseases that weren’t yet ready for prime time. nature.com/articles/s4159…

And now testing the clinical implementation of those discoveries: clinicaltrials.gov/study/NCT05926…
VA’s largest research program is making discoveries to help improve health care for Black Veterans. bit.ly/3SJoluu
Perspective: "A Tale of Two Scores: Comparing Coronary Artery Calcium and Polygenic Risk Scores for the Prediction of Coronary #Heart Disease Events" by @jasonvassy & @marstonMD #MedTwitter #PathTwitter #MedX #LabMedX 👉 buff.ly/4bOnYHR