Bull Group Chemistry
@jamesabull
Organic Chemistry Research Group at Imperial College London. Synthesis; Catalysis; Heterocycles. Updates on group news and papers. Account run by JAB
New orthogonal SuFEx and SNAr reactivity of sulfonimidoyl fluorides and the automated synthesis of sulfonimidamides by @jamesabull and coworkers (@imperialcollege) #OpenAccess 🔓 onlinelibrary.wiley.com/doi/10.1002/ce…
Our work on the divergent synthesis of difluorocyclobutanes, now published in #JOC @JOC_OL. Synthesis of gem-Difluorocyclobutanes: Organolanthanum Enabled Synthesis and Divergent Catalytic Functionalization of gem-Difluorocyclobutanols pubs.acs.org/doi/10.1021/ac…
Interested in strained rings or fluorine for medicinal chemistry - check out Hikaru’s work on divergent synthesis of difluorocyclobutanes, on ChemRxiv: doi.org/10.26434/chemr…
SuFEx and SNAr on Sulfonimidoyl Fluorides - pleased this is now published in @ChemistryEur. Catalytic SuFEx Reactivity of Sulfonimidoyl Fluorides with Functionalized Amines with Automation Applicable Conditions …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ce…
Happy to report our work on catalytic SuFEx with sulfonimidoyl fluorides - and switchable SNAr reacts also. Congrats to Nikki on her paper now on ChemRxiv doi.org/10.26434/chemr…
Electrochemical Copper Catalysis: A Triple Catalytic System for Transient C(sp2)–H Functionalization Through Mediated Electrolysis | @ChemRxiv Congrats Freeman @TszKanMa1 doi.org/10.26434/chemr…

Congrats to Freeman and Peerawat on our recent @ChemRxiv - Synthesis of Cyclic Sulfilimines and Sulfoximines via Copper Mediated C(sp2)–H Sulfanylation of Benzylamines with a Catalytic Transient Directing Group. chemrxiv.org/engage/chemrxi…

Interested in strained rings or fluorine for medicinal chemistry - check out Hikaru’s work on divergent synthesis of difluorocyclobutanes, on ChemRxiv: doi.org/10.26434/chemr…

Happy to report our work on catalytic SuFEx with sulfonimidoyl fluorides - and switchable SNAr reacts also. Congrats to Nikki on her paper now on ChemRxiv doi.org/10.26434/chemr…

** New PhD position ** We are advertising a chemical biology studentship with Profs Vilar and Mann, in collaboration with GSK, with ICB CDT @icbcdt . #automation, #Synthesis, #D2B. Fully funded at UK fees level. findaphd.com/phds/project/d…
Did you miss Ulrich Luecking’s talk about "Sulfoximines in Medicinal Chemistry: Unlocking Novel Opportunities in Drug Design"? In this Flash Talk, Ulrich Luecking, VP and Head of Chemistry at FoRx Therapeutics, explores the untapped potential of sulfoximines in modern drug…
Last update of our "useful link" website: we added a few computational tools and compound databases useful for organic chemists! (Just a start, happy to add more in the future) epfl.ch/labs/lcso/grou…
We are advertising a 2nd fully funded PhD studentship with @TateScience and @icbcdt for October - New dimensions for covalent enantioprobe chemoproteomics #chemicalbiology, #synthesis, #chemoproteomics, #CHfunctionalisation. findaphd.com/phds/project/n…
🌟 Unlock Your Potential in Advanced Molecular Synthesis! Join the MRes in Advanced Molecular Synthesis at @imperialcollege and gain skills and knowledge to excel in the dynamic field of molecular synthesis. 🔗 Learn More and Apply Today! imperial.ac.uk/study/courses/… #Chemistry
🚀 Exciting Opportunity! We're offering 5 studentships for October 2025 entry at @imperialcollege: 🔬 1+3 studentships (1-year MRes + 3-year PhD) 🌍 Open to Home & Overseas applicants 🗓️ Deadline: 7th April 👉Explore the projects & apply now: imperial.ac.uk/chemical-biolo…
We are advertising an exciting PhD studentship related to covalent drug discovery with @TateScience and Vertex pharmaceuticals. Warheads take the strain in chemoproteomics #Synthesis, #Strained_rings, #Chemoproteomics. Applications through ICB CDT @icbcdt: imperial.ac.uk/chemical-biolo…
We are recruiting for a postdoctoral Research Associate in Synthetic Chemistry to work in C-H functionalisation. Come join us @impchemistry! 3-year position. Closing 19-March-2025. shorturl.at/uwERp #Chempostdoc, #CHfunctionalization, #Heterocycles
"Unconventional reactivity of sulfonyl fluorides" sciencedirect.com/science/articl…
The RSC Organic Chemistry Community South-East Regional Meeting will be hosted by Imperial Chemistry @impchemistry on Friday 28th March 2025 with an excellent speaker line-up. For more details, to register, & submit poster abstract (PhD/PDRAs), see here: shorturl.at/vinTH
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Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery | Journal of the American Chemical Society @ImperialSci @imperialcollege @impchemistry #Oxetane #Azetidine #SulfonylFluoride #DrugDiscovery @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Our latest on oxetanes and azetidines. Congratulations and thanks to the team!
Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery | Journal of the American Chemical Society @ImperialSci @imperialcollege @impchemistry #Oxetane #Azetidine #SulfonylFluoride #DrugDiscovery @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Harnessing Oxetane and Azetidine Sulfonyl Fluorides for Opportunities in Drug Discovery | Journal of the American Chemical Society @ImperialSci @imperialcollege @impchemistry #Oxetane #Azetidine #SulfonylFluoride #DrugDiscovery @TotalSyntheses pubs.acs.org/doi/10.1021/ja…