Renato V. Iozzo, MD PhD (Honoris causa)
@iozzo_v
Gonzalo Aponte Endowed Chair Professor. Pathology & Genomic Medicine. Thomas Jefferson University Editor-In-Chief Proteoglycan Research
Nadine Nagy winner of the EBJD mini rooster award talks about her hyaluronan journey from bench to bedside. Many congratulations to Nadine
Dear Pg lovers, Tsao & Ho report on glypican structural features and their impact on Wnt signaling, providing insights into the mechanisms by which glypicans affect Wnt biology making them targets for cancer immunotherapy onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG lovers, Mourão et al report on the challenges & opportunities of the global use of bovine heparin, a strategy to diversify supply chain, reduce reliance on porcine sources & enhance access to critical therapies onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG lovers, Harris et al have characterized heparin interaction with a recombinant fusion protein comprised by Stabilin-2, the major scavenger receptor for hyaluronan & the Hyaluronan receptor for endocytosis (HARE) onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG lovers, Savani et al report on the role of proteoglycans & hyaluronan in normal & aberrant lung development. They provide a novel perspective on their impact on tissue architecture, signaling & repair processes. onlinelibrary.wiley.com/doi/epdf/10.10…
Thank you Rachel We should reconnect after all those years
Being a true anglophile, I trained 35 Manchester students and was Honorary Professor the University of Manchester 2008-16, I am honored to have such a car, also known as Queen’s car often used by her majesty at her holiday home in Balmoral driving around the grounds in a Defender
It is a 1997 Land Rover Defender 110, 300 TDi, a beautiful car that seats 9 passengers and many dogs.
Dear PG lovers, the next tweets are personal but indirectly related to proteoglycans….since I was a teenager in South Italy I always wanted to have this kind of HSPG, and now after a long interval and working in two countries I finally got it..... although is left hand drive
Dear PG lovers, Milesi et al reports on the novel field of nanoscaled therapeutics and the role GAG‐functionalized nanoparticles play in cellular uptake for effective drug delivery, particularly in targeting cancer cells, onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG lovers, Yang & Schmidt provide a novel perspective on the alveolar and endothelial glycocalyces. These structures play a key role in critical illnesses such as sepsis and acute respiratory distress syndrome. onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG lovers, read this comprehensive review by Yu Yamaguchi focused on the important role of Transmembrane protein 2 (TMEM2) as a functional cell surface hyaluronidase. TMEM2 adds a new dimension to hyaluronan biology. onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG Lovers, in the SI on Heparin & Heparinoids, Reinbold et al reports that TMEM230 an ER protein that controls NOTCH signaling can also regulate glycan/glycoconjugate processing in autoimmune and malignant disorders onlinelibrary.wiley.com/doi/epdf/10.10…
Read this great retrospective of John Couchman on the discovery of focal adhesions and the crucial role of Syndecan-4 in this process leading to the involvement of kinases, microfilament dynamics, and ion channels. onlinelibrary.wiley.com/doi/epdf/10.10…
Dear PG Lovers, in the SI on Heparin & Heparinoids, Gorzelanny et al have successfully applied super-resolution microscopy and single-molecule force spectroscopy to study the structural configuration of cell surface HS. onlinelibrary.wiley.com/doi/epdf/10.10…
I never tweet about me, but this time I like to share with you an event that has made me very happy, humbled and honored. @rjweiss86
In 2024 we published 24 papers doubling 2023 papers with 14,787 full text views, 643 views/article. We already published 10 papers in January of 2025, and launched 5 special issues. Thus, I believe that the number of published articles will follow the same upward trajectory
Dear PG lovers, in the next tweets I provide an update on Proteoglycan Res Metrics. We plan to apply to Scopus and PubMed indexing in the Spring. So, we have only data regarding full text views. In 2023 we published 12 papers with ~4500 views, or an average of 375 views/paper ….
