IntAct at EBI
@intact_project
The Molecular Interactions Database at the EMBL-EBI. Open Source Framework for Molecular Interactions. Also follow➡️@complexportal.
Excited to share the global proximity interactome in the Human Macroautophagy Pathway! (See: tinyurl.com/bdfaeztn) Study uncovers novel role of OSBPL family lipid transport proteins as new players in autophagy.See IntAct: tinyurl.com/34ksav36 #Macroautophagy #BrumellLab
Excited to share the global proximity interactome in the Human Macroautophagy Pathway!(PMID: 34524948). Study uncovers novel putative connections including the OSBPL family lipid transporters, new players in autophagy.See IntAct: tinyurl.com/34ksav36 #Macroautophagy#BrumellLab
Want to learn more about macromolecular complexes? Register for our webinar on 𝗝𝘂𝗹𝘆 𝟵𝘁𝗵, 𝟮𝟬𝟮𝟱! Discover more about our latest updates including the Complex Navigator & the integration of ML-predicted complexes (huMap3.0 & MuSIC). ➡️ Register:tinyurl.com/bdy6wttv
UniProt is a world-leading, freely accessible data resource that provides protein sequence and functional information to scientists worldwide. So what is the value of UniProt for the global scientific community? #FAIRdata #Bioinformatics
Find the true value of UniProt! A @PathOS EU-funded study by @CSIL finds @UniProt users save up to €5,475 & 219 hours/year. UniProt boosts research, biotech & healthcare by integrating 180+ databases with expert curation of publications. Read our Blog 👉 insideuniprot.blogspot.com/2025/06/unipro…
IntAct's dataset of the month features 75 cancer-associated missense variants in retinoblastoma tumor suppressor protein (PMID:39938803). Visit IntAct & explore detailed expert-curation of variants, binding domains and biophysical parameters (tinyurl.com/4rsx8754). #Cancer
May is skin cancer awareness month! We're highlighting Telomerase holoenzyme complex (CPX-265) featuring TERT(UniProt:O14746). See the complex in tinyurl.com/mt7u4wbs & visit UniProt for all melanoma-associated proteins tinyurl.com/mryjvyu7 #MelanomaAwareness, #SunSafety🧴
It is Skin Cancer awareness month! Explore manually curated interactomes of proteins associated with familial melanoma in IntAct. Access the network in IntAct (tinyurl.com/26tc7xtm). #IntAct_EBI, #ComplexPortal, #UniProt, #MelanomaAwareness, #SunSafety, 😎📷🧴
Thrilled to announce that the protein–protein interactions of 396 SLC transporters, from the RESOLUTE project, is now integrated into IntAct! Congratulations to #Superti-FurgaLab, #FabianFrommelt Explore the interactome at ebi.ac.uk/intact/search?…
Excited to have integrated data from ‘Systematic discovery of mutation-directed neo-protein-protein interactions in cancer’ in IntAct (PMID: 35512704). #tumor #PPI #mutations Explore the interactome at ebi.ac.uk/intact/search?…
IntAct is expanding its Inflammatory Bowel Disease dataset (lnkd.in/ejkr8tKx)! Our latest addition is the lncRNA GATA6-AS1 interactome, from K.E. Sosnovski et al. (2023) in Caco-2 cells (lnkd.in/eiYaFSdK). ➡️ Learn more about this! (lnkd.in/e2RSQEZZ)
IntAct release 250 is out! 1,702,367 binary interactions from 23,612 manually curated publications ebi.ac.uk/intact/about#s… (in sync with UniProt release 2025_02)
Interested in RASopathy and RAS-driven cancers? This month we feature SHOC-MRAS holophosphatase complexes.....CPX-25716, CPX-25719, CPX-25720. Visit the Complex Portal to learn more!
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two biocurators at the Complex Portal.
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two members of the IntAct team.
👩🔬 Today is International Women and Girls in Science day! 🧪 To celebrate we’re shining the spotlight on two members of the IntAct Team.
Start 2025 with a look at the Prefoldin-like co-chaperone complex (tinyurl.com/3p8b2arh), it’s multi-functional with roles in proteostasis, protein folding, assembly and stabilization. Visit us to learn more about this and Prefoldin (CPX-6149) & PAQosome (CPX-6145) complexes!
Join us with @uniprot to discover two automated annotation systems UniRule and ARBA and their use in functional annotation of proteins. Registration is free but essential ebi.ac.uk/training/event… @emblebi #proteomics #OpenAccess