International Headache Society

We are pleased to announce and congratulate the authors on their paper, “Higher socioeconomic status is associated with dispensation of monoclonal antibodies against calcitonin gene-related peptide in migraine: A nested case-control study” which has been selected as the Editor’s…

✨🧠 New Topical Collection in Cephalalgia! ✨🧠 "Toward International Classification of Headache Disorders – 4 (ICHD-4)" 📍OPEN TO SUBMISSIONS As we look ahead to the next edition of the ICHD, this collection invites high-level contributions to address current limitations,…

📢 Call for Papers: Digital Headache 🧠 @JCephalalgia is the official journal of the International Headache Society @ihs_official , a leading international scientific society dedicated to advancing the understanding and treatment of headache disorders. Introduction The…

New in Cephalalgia! How does migraine with aura (MA) alter brain structure beyond the visual cortex? 🧠 ⚡Using structural MRI and network-based analysis, this study reveals altered grey-matter (GM) network topology in MA: ➡️ Right lingual gyrus: Increased nodal degree in MA…

How does stress trigger facial pain in mice—and how can we reverse it? A recent study using a mouse model investigated the mechanisms behind stress-induced facial mechanical hypersensitivity, highlighting the role of the HPA axis and melanocortin signaling: ．Metyrapone (a…

New in Cephalalgia! Fibromyalgia (FM) is a common comorbidity in chronic migraine (CM), but how it affects treatment response has remained unclear. 📌 This prospective, proof-of-concept study compared treatment responsiveness to flunarizine in patients with: - Chronic migraine…

How is the endocannabinoid system involved in medication overuse headache (MOH)? This study investigated alterations of AEA-related ECS components in PBMCs from patients with MOH. Results showed that: ．MOH patients exhibited lower FAAH gene expression but higher FAAH protein…

Socioeconomic disparities in access to migraine therapy persist—even in publicly funded healthcare systems. In a population-based nested case-control study from Region Stockholm (N = 52,996), researchers examined the association between socioeconomic status (SES) and first-time…

💥 What is PACAP — and why is it making waves in migraine research? PACAP (pituitary adenylate cyclase-activating polypeptide) is emerging as a promising target for new migraine treatment. Curious how this neuropeptide could change the game? 🧠 Dive into the latest research…

🧒🧠 Call for Papers: Cephalalgia Topical Collection – Headache in Children and Adolescents Guest Editors: Andrew Hershey, Aynur Ozge, Massimiliano Valeriani Headache disorders in pediatric populations are common, complex, and often under-recognized. This Topical Collection of…

New in Cephalalgia Reports! A cross-sectional study examines real-world data from patients with cluster headache (CH) referred to a tertiary headache center. Key findings: ✔️ 54% had chronic CH ❌ 34% lacked first-line acute therapy ❌ 55% had not received guideline-recommended…

The International Headache Congress (IHC 2025) is bringing together top global experts from 30+ countries to share the latest in headache diagnosis, treatment, and research. ihc2025.org 📍 São Paulo, Brazil 📅 10–13 September 2025

#SundayQuiz Answer: A is Incorrect. This week’s question asked: Which of the following statements about ICHD-3 criteria for Primary Cough Headache (4.1) is INCORRECT? Let’s break it down: ❌ A) It lasts between 1 second and 1 hour This is incorrect. According to ICHD-3,…

New Research published in @Cephreports! Combined #SPG and #GON blocks for patients with refractory #cluster headache @ihs_officialhttps://doi.org/10.1177/25158163251355554 @JCephalalgia @Simona_Sacco_

📢 We are delighted to officially welcome the 2025/2026 Cephalalgia Reviewer Academy Fellows! 🎉 These outstanding early-career researchers from around the world have been selected for their commitment to excellence in headache research and scientific publishing. Over the next…

#SundayQuiz of the week Regarding the ICHD-3 diagnostic criteria for primary cough headache, which of the following statements is INCORRECT? A) It lasts between 1 second and 1 hour B) A Valsalva manoeuvre can also be a trigger

Throwback Thursday! Do you remember iHEAD 2023 in Seoul? We welcomed 93 delegates from 30 countries to exchange ideas, foster friendships, and advance headache care together. See you at IHC 2025 in São Paulo! 🌎✨ #tbt #IHC2025 #SãoPaulo

The IHS Juniors Group is now accepting nominations for the 2025 elections! The deadline for nominations is 21 July 2025. Don’t miss this chance to represent your region and contribute to the future of headache medicine. Nominations must be submitted using the official…

Greetings from Dr Karina Vélez Jiménez, Board Member of the International Headache Society 🇲🇽. For the first time, the International Headache Congress will be held in Latin America. Join us in São Paulo, Brazil, from 10 to 13 September 2025. 🌐 Register now:…