Iakovos Lazaridis
@iaklaz
McGovern Institute for Brain Research, MIT
Interested in dopamine regulation? Don’t forget the astrocytes! We’re excited to share our new preprint on astrocyte-dopamine interactions in the dorsal striatum and behavioral state transitions. @biorxiv_neursci, @mcgovernmit, @AnnMGraybiel biorxiv.org/content/10.110…

My final postdoc paper from the Golshani lab is finally out! How does inhibition regulate memory-encoding pyramidal sequences? We used kHz-rate voltage imaging of mouse CA1 PV & SST cells during a working memory task with odors. nature.com/articles/s4159…
Researchers are flocking to the social-media platform Bluesky, hoping to recreate the good old days of Twitter go.nature.com/410rxYq
Job alert 🚨: I’m looking for a creative, ambitious, and dedicated postdoc to join me on this quest; so many exciting questions about how cortex and sub cortical structures (including spinal cord) drive adaptive motor control. Large scale 2P (limited labs 🌎 have this tech),…
How does sensorimotor (S1/M1) cortex support adaptive motor control? Come find out in our latest preprint, which spans the development of a full adult forelimb model + physics simulations, neural-modeling for control, complex 🐭behavior 🕹️, large-scale imaging, and of course…
Cortical norepinephrine-astrocyte signaling critically mediates learned behavior biorxiv.org/cgi/content/sh… #biorxiv_neursci
The @NeuroAlc Christmas Meeting is back for 2025! 🎄🧠 A great chance for postdocs and PIs in neuroscience to meet, share ideas and connect with us. Join us in Alicante, Dec 18–19. Apply by Oct 15! #NeuroScience #ChristmasMeeting_IN
Call open for the 22nd @NeuroAlc Christmas Meeting! 🧠🎄 Dec 18–19, 2025 📍Alicante, Spain Open to postdocs & junior PIs in neuroscience. 🗓️ Apply by Oct 15: [email protected] #NeuroScience #ChristmasMeeting_IN @CSIC @CSICval @UniversidadMH @umhsapiens
🚨I’m excited to share that the first piece of my postdoc work with @MarkHowe72 is out! 🧵⬇️nature.com/articles/s4146…
Save the date and join us for a webinar about cholinergic interneurons, hosted by the Swedish Basal Ganglia Society. We are excited to have two distinguished speakers: Stephanie Cragg and Mark Howe. Everyone is welcome and no registration is required! swebags.ebrains.se/events/choline…
The ‘go’ and ‘no-go’ pathways in the basal ganglia are not the only pathways that control movement, as a new study reveals two additional circuits that modulate dopamine and movement. By @claulopezneuro thetransmitter.org/basal-ganglia/…
Excited to share our new study! We identify Anxa1 neurons as particularly vulnerable in Parkinson’s disease. We also show their crucial role in prodromal-phase bradykinesia and procedural motor learning.
Call open for the 22nd @NeuroAlc Christmas Meeting! 🧠🎄 Dec 18–19, 2025 📍Alicante, Spain Open to postdocs & junior PIs in neuroscience. 🗓️ Apply by Oct 15: [email protected] #NeuroScience #ChristmasMeeting_IN @CSIC @CSICval @UniversidadMH @umhsapiens
Excited to organize this year's annual meeting of the Instituto de Neurociencias @NeuroAlc with @FemeniaLab and @FelixFelxfel! We have a nice lineup of speakers and are thrilled to welcome our keynote speaker, Julien Bouvier @julbouvier from @NeuroPSI_saclay. #ChristmasMeeting_IN
Our XXI Christmas Meeting is almost here! 🎄✨ Check out the full program and get ready👀🎁 #ChristmasMeeting_IN
Excited to share @AmpatzisLab and @KizilLab's's new paper on #zebrafish 's intracardiac nervous system (IcNS), highlighting the presence of pacemaker-like neurons that partake in heart rhythm—linking cardiac and neuroscience research. nature.com/articles/s4146…
Check out our latest preprint - a new view on the mouse PFC!
Our new study is out! biorxiv.org/content/10.110… We (@CarlenLab) mapped the mouse PFC using single-unit activity! We recorded ~23,000 neurons across cortical/subcortical regions and profiled spont. firing patterns to reveal what separates the PFC from other brain regions. 1/n
Cytoarchitecture has been the dominant, ever-changing canvas to study brain regions. We here started with a clean slate and instead approached organization of brain regions by profiling spontaneous activity of single neurons. Do PFC neurons hold unique firing properties? 2/n
Our new study is out! biorxiv.org/content/10.110… We (@CarlenLab) mapped the mouse PFC using single-unit activity! We recorded ~23,000 neurons across cortical/subcortical regions and profiled spont. firing patterns to reveal what separates the PFC from other brain regions. 1/n
We did it. We killed neuro twitter and it's resuscitation it's happening somewhere else. Come join us! thetransmitter.org/community/huge…
A Prefrontal Cortex Map based on Single Neuron Activity biorxiv.org/cgi/content/sh… #biorxiv_neursci
New preprint w/ @lab_plotkin about cholinergic interneurons causing local serotonin release in striatum and how this is related to obsessive-compulsive disorder biorxiv.org/content/10.110… For the story, read on 1/9
The paper, by first author @iaklaz, appears today @CurrentBiology 👇 sciencedirect.com/science/articl… @mitbrainandcog @ScienceMIT
The Graybiel lab has identified brain pathways that control dopamine release and may influence our motivation to take action. mcgovern.mit.edu/2024/10/23/bra…