Huiluo Cao 曹慧荦

@hlcao

microbial genomics and evolution, antibiotic resistance, bioinformatics, Pseudomonas aeruginosa, pneumococcus, human microbioa, @hkuniversity

Hong Kong

Joined May 2011

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3KFollowers

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Huiluo Cao 曹慧荦@hlcao · Oct 5

We launched a BMC Genomic Data Collection that seeks to attract advances in the field of genomics of antibiotic-producing microorganisms, as well as other genomics work. Welcome any interested to contribute. biomedcentral.com/collections/ga…

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Huiluo Cao 曹慧荦@hlcao · Jul 11

The role of metabolism in shaping enzyme structures over 400 million years | Nature nature.com/articles/s4158…

hlcao's tweet card. Nature - By combining structural biology and evolutionary genomics analyses, the evolution of enzymes over 400 million years is shown to be governed by catalytic function, metabolic network...

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Huiluo Cao 曹慧荦@hlcao · 3 h

Viromics approaches for the study of viral diversity and ecology in microbiomes | Nature Reviews Genetics nature.com/articles/s4157…

hlcao's tweet card. Nature Reviews Genetics - In this Review, Roux and Coclet outline current viromics approaches and discuss how they have contributed to our growing understanding of viral genomic diversity, focusing...

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Huiluo Cao 曹慧荦@hlcao · 10 h

Hotspots of genetic change in Yersinia pestis | Nature Communications nature.com/articles/s4146…

hlcao's tweet card. Nature Communications - The relative contributions of mutation rate variation, selection, and recombination in shaping genomic variation in bacterial populations remain poorly understood. Here, the...

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Huiluo Cao 曹慧荦@hlcao · Jul 22

Gifting future scientists the past through well-preserved specimens of modern microbial ecosystems | Nature Communications nature.com/articles/s4146…

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Huiluo Cao 曹慧荦@hlcao · Jul 22

Segatella copri and gut microbial ammonia metabolism contribute to chronic kidney disease pathogenesis | Nature Microbiology nature.com/articles/s4156…

hlcao's tweet card. Nature Microbiology - Using human data and mice models, it was revealed that assimilation of ammonia by a gut microbe prevents its harmful accumulation that can impair kidney function.

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Huiluo Cao 曹慧荦@hlcao · Jul 21

Global emergence and transmission dynamics of carbapenemase-producing Citrobacter freundii sequence type 22 high-risk international clone: a retrospective, genomic, epidemiological study - The Lancet Microbe thelancet.com/journals/lanmi…

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Huiluo Cao 曹慧荦@hlcao · Jul 20

Controlled colonization of the human gut with a genetically engineered microbial therapeutic | Science science.org/doi/10.1126/sc…

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Huiluo Cao 曹慧荦@hlcao · Jul 18

Comprehensive taxonomic identification of microbial species in metagenomic data using SingleM and Sandpiper | Nature Biotechnology nature.com/articles/s4158…

hlcao's tweet card. Nature Biotechnology - Novel microbial species in metagenomes are identified using conserved regions within universal marker genes.

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Huiluo Cao 曹慧荦@hlcao · Jul 17

Global dissemination of npmA mediated pan-aminoglycoside resistance via a mobile genetic element in Gram-positive bacteria | Nature Communications nature.com/articles/s4146…

hlcao's tweet card. Nature Communications - The authors investigate the distribution of the aminoglycoside resistance gene npmA in Gram-positive bacteria via a mobile genetic element, highlighting its global presence...

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Huiluo Cao 曹慧荦@hlcao · Jul 17

Prophages block cell surface receptors to preserve their viral progeny | Nature nature.com/articles/s4158…

hlcao's tweet card. Nature - Zip promotes the accumulation of free phages in bacterial lysogen communities, safeguarding phage progeny.

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Huiluo Cao 曹慧荦@hlcao · Jul 17

Identification of medication–microbiome interactions that affect gut infection | Nature nature.com/articles/s4158…

hlcao's tweet card. Nature - An analysis of prescription medications shows that several non-antibiotic drugs, such as the heart medication digoxin, can reduce the immune response to pathogens and increase the risk of...

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Huiluo Cao 曹慧荦@hlcao · Jul 13

Functional amyloid proteins confer defence against predatory bacteria | Nature nature.com/articles/s4158…

hlcao's tweet card. Nature - Escherichia coli uses curli fibres, oligomers of the functional amyloid CsgA, as a barrier to protect against the predatory bacteria Bdellovibrio bacteriovorus and Myxococcus xanthus in a...

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Huiluo Cao 曹慧荦@hlcao · Jul 12

Defining the ecological strategies of phytoplankton associated bacteria | Nature Communications nature.com/articles/s4146…

hlcao's tweet card. Nature Communications - Phytoplankton-bacteria interactions regulate the health of marine ecosystems; however, how these interactions are established remains unclear. Here, the authors isolate 15...

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Huiluo Cao 曹慧荦@hlcao · Jul 11

The generative era of medical AI - ScienceDirect sciencedirect.com/science/articl…

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Huiluo Cao 曹慧荦@hlcao · Jul 11

Antimicrobial peptides: structure, functions and translational applications | Nature Reviews Microbiology nature.com/articles/s4157…

hlcao's tweet card. Nature Reviews Microbiology - In this Review, Franco and colleagues explore the structural and functional diversity of antimicrobial peptides (AMPs), their mechanism of action, recent advances in...

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Huiluo Cao 曹慧荦@hlcao · Jul 10

Metatranscriptomics uncovers diurnal functional shifts in bacterial transgenes with profound metabolic effects: Cell Host & Microbe cell.com/cell-host-micr…

hlcao's tweet card. Flores Ramos et al. use metatranscriptomics to reveal diurnal functional shifts in microbes under time-restricted feeding, identifying a Dubosiella newyorkensis bile salt hydrolase (DnBSH1) with...

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Huiluo Cao 曹慧荦@hlcao · Jul 7

BEAST X for Bayesian phylogenetic, phylogeographic and phylodynamic inference | Nature Methods nature.com/articles/s4159…

hlcao's tweet card. Nature Methods - BEAST X advances Bayesian phylogenetic, phylogeographic and phylodynamic analysis by incorporating a broad range of complex models and leveraging advanced algorithms and techniques...

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Huiluo Cao 曹慧荦@hlcao · Jul 6

Staphylococcus aureus LukMF′ targets neutrophils to promote skin and soft tissue infection | Science Advances science.org/doi/10.1126/sc…

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Huiluo Cao 曹慧荦@hlcao · Jul 6

Droplet microfluidics–based detection of rare antibiotic-resistant subpopulations in Escherichia coli from bloodstream infections | Science Advances science.org/doi/10.1126/sc…

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Huiluo Cao 曹慧荦@hlcao · Jul 6

The gut microbiome–germline axis: Does a prospective father’s gut microbiota matter? | Science science.org/doi/10.1126/sc…

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