Logan Bartholomew
@gloganb
UC Berkeley Organic Chemistry PhD @SarpongGroup from KY. NSF GRFP. BS, GWU, 2020. Sometime baker, guitarist, delusional golfer, and skiing addict.
This project was a ton of fun to put together and wouldn’t have been possible without the tremendous efforts of this team. Check out our now-published cheminformatic platform for skeletal edit development prioritization below! bit.ly/3Dq9Mbo
Congrats to @gloganb & collaborators @lucaskaras1 (@Sigman_Lab) & Reilly & @Charles_chem (Merck) on the publication of our work on a cheminformatic analysis of core-atom transformations in pharmaceutically relevant heteroaromatics in J. Med. Chem. tinyurl.com/42re37pd
Congrats to @gloganb, @SojungKim20, Yusuke and collaborators @BarnerKowollik, @GileadSciences, @Merck on our indazole to benzimidazole conversion onlinelibrary.wiley.com/doi/10.1002/an… coordinated with @LeonoriLab onlinelibrary.wiley.com/doi/10.1002/an…
To round out our work on these photomediated ring contractions of saturated heterocycles, I'm excited to share this collaborative story about uncovering interesting enantioselectivity trends in this system, out now in @J_A_C_S!
Congrats to @SojungKim20, our collaborator Jordan(@Sigman_Lab), our collaborators from Merck and former group members Justin & Yasuki on the publication of our work on understanding the enantioselectivity of our photomediated ring contraction in @J_A_C_S! doi.org/10.1021/jacs.4…
The final chapter of my PhD with @SarpongGroup at @UCB_Chemistry is published! Check out our full story of how we approached the synthesis of Daphniphyllum alkaloids inspired by molecular complexity scoring, out now in @J_A_C_S 🎉 pubs.acs.org/doi/10.1021/ja…
We’re excited to share our quantitative assessment of the potential impact of skeletal edits, now on ChemRxiv! This cheminformatic platform was developed with @lucaskaras1 from @Sigman_Lab and Reilly Eason & @Charles_chem at #MerckChemistry. tinyurl.com/yc4jev9k

Ever thought about quantifying molecular complexity? We wrote a Perspective on how modeling this fascinating concept can lead to new insights in synthetic chemistry. Check it out in @NatRevChem! 🎉 @SarpongGroup nature.com/articles/s4157…
My total synthesis of baphicacanthcusine A is out now in @angew_chem. It has been a fascinating journey learning about these unique molecules and I’m really proud to tell this story! onlinelibrary.wiley.com/doi/10.1002/an…
Our investigation into the photomediated ring contraction of saturated heterocycles is out in @J_A_C_S! Excited to finally share my inaugural 1st author, multi-part story that blends synthesis, mechanistic & wavelength-dependent insight, and computations. tinyurl.com/hccapy9d
Guilty as charged
F*** it. Using "editing" in the title of my next paper. Suzuki Rxn? Editing via C-C Bond Formation and Halogen/Boron Deletion. 3+2? Editing via strategic rearrangement of electrons to form a cycle. Dearomatization of Pyridinium? Editing via the removal of aromaticity.
14N to 15N Isotopic Exchange of Nitrogen Heteroaromatics through Skeletal Editing | Journal of the American Chemical Society @UUtah @UtahChemistry @UCBerkeley @UCB_Chemistry @Sigman_Lab @SarpongGroup #Hetarenes #Skeletal #Editing @TotalSyntheses pubs.acs.org/doi/10.1021/ja…
Our azine N-isotope exchange is out now in @J_A_C_S! Excited to share this story with a few twists in the @SarpongGroup with the @Sigman_Lab and @Charles_chem from #MerckChemistry. Big thanks to @SamLKraus, @lucaskaras1, and this awesome team. bit.ly/15Nie
Congrats to @gloganb , @SamLKraus and our collaborators at #Merckchemistry and the @Sigman_Lab on the publication of our work on 14N to 15N exchange in azines in JACS! pubs.acs.org/doi/10.1021/ja…
Great day meeting at @UCB_Chemistry for the #MerckChemistry lecture yesterday. Enjoyed the panel discussion in the AM with students!
Fourth year @gloganb, placed 2nd in the poster session for his great poster on his recent 14N-to-15N skeletal edit of nitrogen heteroaromatics work. Congrats Logan! We’re so proud of you! 5/5
15N Incorporation into pyridines via NTf-Zincke imine intermediates now on @ChemRxiv . Congrats to Hillary, David, Marie, Kaila, and Jeff from my lab: tinyurl.com/ytbh3nem See related work from @SarpongGroup @Sigman_Lab/ Smith/Feuillastre-Audisio
Grateful to have been a part of this awesome team and work with #MerckChemistry and the @Sigman_Lab! Excited to share my new first author paper on an isotopic labeling strategy for nitrogen heteroaromatics using skeletal editing. Check it out on ChemRxiv: rb.gy/990eaq.
Swap it out! Congrats @gloganb and @SamLKraus with @Charles_chem (#MerckChemistry) and @lucaskaras1 (@Sigman_Lab) on a 14N-to-15N skeletal edit of nitrogen heteroaromatics (rb.gy/990eaq). Great related works from Joel Smith, Feuillastre/Audisio, and @AndyMcNally367!
Skeletal Editing of Pyrimidines to Pyrazoles by Formal Carbon Deletion @SarpongGroup @UCBerkeley @UCB_Chemistry @TotalSynthesis @TotalSyntheses #Editing #Pyrimidines #Pyrazoles #Carbon #Deletion pubs.acs.org/doi/10.1021/ja…
Excited to get this work out! Check out my inaugural first author paper on our method for the conversion of pyrimidine to pyrazole a out now in @J_A_C_S.
Cut it out! @gloganb and Filippo's publication of a formal deletion of carbon to convert pyrimidines to pyrazoles is out in @J_A_C_S pubs.acs.org/doi/10.1021/ja…