garth rapeport

@garthrapeport

Visiting Prof, NHLI, Imperial College , F Prime and Rigimmune Drug discovery for life-threatening viral and fungal infections.

London, England

Joined October 2012

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garth rapeport@garthrapeport · Jun 27

Gilead blames low RSV infection rates last season for scrapping 2 obeldesivir trials fiercebiotech.com/biotech/gilead…

garthrapeport's tweet card. Gilead Sciences has blamed the low rate of respiratory syncytial virus (RSV) infections last season for ending two midstage trials of obeldesivir. | Gilead has blamed the low rate of respiratory...

garth rapeport Retweeted

Andrew Pannu@andrewpannu · Jul 22

Another $2B COPD opportunity just hit a brick wall. Yesterday, the Roche / Amgen IL-33 Astegolimab missed its primary endpoint in the Ph3 ARNASA study - the second failure of an IL-33 in a few months, after the Regeneron / Sanofi AERIFY-2 study of Itepekimab failed in May…

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garth rapeport@garthrapeport · Jul 23

Roche's COPD drug flunks phase 3 trial, denting hopes of approval this year .Another blow for IL33 targeted approach for COPD. fiercebiotech.com/biotech/roches…

garthrapeport's tweet card. Roche’s hopes of getting its chronic obstructive pulmonary disease (COPD) drug astegolimab to regulators this year have taken a hit after the anti-ST2 monoclonal antibody

garth rapeport@garthrapeport · Jul 23

Found: a human gut microbe that makes cancer therapy more effective in mice nature.com/articles/d4158…

garthrapeport's tweet card. Nature - Cancer therapies called checkpoint inhibitor drugs, which ratchet up the immune system, work better when this bacterium is around.

garth rapeport@garthrapeport · Jul 22

Sanofi tightens grip on RSV, paying $1.15B upfront for Vicebio and boosting its pipeline beyond mRNA ftp.bdlsummit.com/biotech/sanofi…

garthrapeport's tweet card. Sanofi has struck a deal to buy Vicebio for $1.15 billion upfront, securing preclin | Sanofi has struck a deal to buy Vicebio for $1.15 billion upfront, securing preclinical and phase 1 vaccine...

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garth rapeport@garthrapeport · Jul 21

It is now believed that every known neurodegenerative disease — from Alzheimer’s to Parkinson’s to ALS to Huntington’s to general dementia — involves a prion-like protein lrb.co.uk/the-paper/v47/…

garthrapeport's tweet card. How and why do proteins, which are produced by our body to build structures (such as skin and muscle) or carry out tasks...

garth rapeport@garthrapeport · Jul 18

As 'the most infectious virus' roars back to life, the first measles treatment remains a pipe dream fiercebiotech.com/research/you-j…

garthrapeport's tweet card. As measles cases surge to record levels in the U.S., Department of Health and Human Services (HHS) Secretary R | As measles cases surge to record levels in the U.S., Department of Health and Human...

garth rapeport@garthrapeport · Jul 11

Fungal infections are getting harder to treat nbcnews.com/health/health-… via @nbcnews

garthrapeport's tweet card. The fungus Aspergillus fumigatus tops the World Health Organization's list of worrying fungal diseases. It's growing increasingly resistant to the first-line drug used to treat it.

garth rapeport@garthrapeport · Jul 9

Merck nears about $10 billion deal for London-based lung therapy firm Verona, FT reports reuters.com/business/healt…

garthrapeport's tweet card. Merck said on Wednesday it will acquire UK-based Verona Pharma for about $10 billion, gaining a promising respiratory treatment as it faces pressure to diversify beyond its blockbuster cancer drug...

garth rapeport@garthrapeport · Jul 8

Novartis gets approval for first malaria drug for babies and children reuters.com/business/healt…

garthrapeport's tweet card. Novartis said on Tuesday it had received approval in Switzerland for Coartem Baby, which it said was the first drug to treat malaria in babies and very young children.

garth rapeport@garthrapeport · Jul 8

Many U.S. babies may lack gut bacteria that train their immune systems sciencenews.org/article/babies…

garthrapeport's tweet card. Too little Bifidobacterium, used to digest breast milk, in babies' gut microbiomes can increase their risk of developing allergies and asthma.

garth rapeport@garthrapeport · Jun 30

New Antifungal Drug Olorofim Shows Efficacy in Treating Resistant Fungal Infections contagionlive.com/view/new-antif… via @contagionlive

garth rapeport@garthrapeport · Jun 30

Monoclonal Antibody Shows 84% Relative Risk Reduction of Symptomatic COVID-19 Vs Placebo contagionlive.com/view/monoclona… via @contagionlive

garth rapeport@garthrapeport · Jun 29

Sweetener saccharin shows surprise power against antibiotic resistance | Brunel University of London brunel.ac.uk/news-and-event…

garth rapeport Retweeted

Eric Topol@EricTopol · Jun 28

Good news: the very low current levels of SARS-CoV-2 in wastewater, even in places where the new variants are prevalent (XFG, NB.1.8.1), suggest that any summer wave will be limited, not like previous ones cdc.gov/nwss/rv/COVID1…

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garth rapeport@garthrapeport · Jun 28

New viruses discovered in bats in China could be the next pandemic threat sciencedaily.com/releases/2025/…

garth rapeport@garthrapeport · Jun 27

Supersticky air filter mimics human nose cen.acs.org/materials/Nose… via @cenmag

garth rapeport@garthrapeport · Jun 25

A single infusion of a stem cell-based treatment may have cured 10 out of 12 people with the most severe form of type 1 diabetes. One year later, these 10 patients no longer need insulin. The other two patients need much lower doses nejm.org/doi/full/10.10…

garth rapeport@garthrapeport · Jun 25

Airborne Fungal Spores May Predict Short-Term Surges in COVID-19 and Influenza environmental exposures may play a larger role in triggering respiratory virus activity than previously recognized contagionlive.com/view/airborne-… via @contagionlive

garth rapeport@garthrapeport · Jun 25

Tuberculosis succumbs to a new strategy The work “opens up a whole new area of drug discovery possibilities for TB and maybe for other bacteria as well cen.acs.org/pharmaceutical… via @cenmag