Daniel De Carvalho
@decarvalho_lab
Scientist working on Cancer Epigenomics, Immunology, Liquid Biopsy, and Transposable Elements. Faculty @pmcancercentre and @UofTmedicine. Founder, http://Adelabio.com
Excited to have this paper out @Annals_Oncology with a concomitant oral presentation @myESMO #ESMO24 ! This is the culmination of our original cfMeDIP-seq work supported by @thePMCF into a clinical validation study for a tissue-agnostic MRD test in Head & Neck cancer.
📢@ESMO24 concomitant paper: Clinical validation of a tissue-agnostic genome-wide methylome enrichment MRD assay for head and neck malignancies. #ESMO24 #HeadandNeckCancer @adela_bio @UHN_Research @decarvalho_lab @ScottBratman tinyurl.com/2bkueo7a
Are you currently in the ERE related field and want to find new collaborative opportunities? Join our Chairs @ChiappinelliLab, @shenhui1986, @twang5 & @paultaowu at the upcoming Endogenous Retrotransposable Elements & Human Diseases Conference this November! #EREHD25 🎙️Talk…
Don't forget to register for #EREHD25! Our talk submission deadline has been extended to 12 JUNE 2025, so submit your abstract today to join our incredible speaker line up in Mexico this November 🇲🇽 🔗bit.ly/4kHWbw0
When you are in Milan for #ESHG25 and bump into the OG of interdisciplinary research..
Europe pledges half a billion euros to lure scientists as Trump battles universities | Reuters reuters.com/science/eus-vo…
Thank you @GairdnerAwards! I'm truly humbled and grateful for this recognition. Science is never a solo journey and this award reflects the hard work, creativity, and persistence of many amazing scientists I had the privilege to work with.
Congratulations to the 2025 Canada Gairdner Award laureates! This year’s laureates represent some of the world’s most significant biomedical and global health research and discoveries. Find out more about these incredible scientists and their award-winning research here:…
Dr. De Carvalho is awarded “For the ground-breaking discovery of the role of transposable elements in regulating anti-tumour immunity through viral mimicry, which holds transformative potential for cancer therapy, and for pioneering the development of a novel blood-based test for…
From the April issue: Chronic #ViralMimicry Induction Following #p53 Loss Promotes Immune Evasion brnw.ch/21wRRjh By @CharlesIshak @SajidMarhon @DeCarvalho_Lab and colleagues @UHN @pmcancercentre @MDAndersonNews
Ever wonder why RNA and protein levels often don't match up? m6A RNA modification could be the missing link. Our work, the first m6A epitranscriptome map in prostate cancer, is out now in Nature Genetics! Huge thanks to collaborators+support from @PCFnews, @tfri_research &more
This RNA modification drives prostate cancer progression A study by @UHN & @UCLAHealthJCCC found m6A RNA modification promotes prostate tumour growth and relapse. It boosts the production of a cell movement molecule to aid cancer metastasis. @NatureGenet: nature.com/articles/s4158…
New Links: Cancer and Immune Evasion🧬 Recent study found that cancer cells without the tumour suppressor protein p53 become more resistant to the body's immune response. A study led by @decarvalho_lab at @UHN’s @pmcancercentre. uhnresearch.ca/news/new-links…; doi.org/10.1158/2159-8…
Registration for #eshg2025 is now open. Register now and profit from early bird rates until April 10, 2025: buff.ly/LTpMXcc Looking forward to welcoming you in Milan!
Scientists @PMResearch_UHN have uncovered how cancer can evade immune defenses after losing a key tumour-suppressing gene. These findings implicate repetitive elements in DNA and may unlock new targets for cancer interception. Read more ➡️ uhnresearch.ca/news/new-links…
#UofT among top 10 universities powering global innovation 📊 uoft.me/bgS
Normal and Abnormal Methylation Patterns and Detection: Ting Wang, Tommy Kaplan, and Daniel D. De Carvalho will address this topic in a plenary session at the #AACRmethylation25 Special Conference (February 1-4, San Diego). brnw.ch/21wPiXS @twang5 @decarvalho_lab