Diego Martins

I’m excited to share an R package that we’ve created for mapping scRNA-seq data across normal and malignant hematopoiesis! We've used this to identify hematopoietic stem cells from healthy tissues and map leukemia cells from hundreds of patients. 1/6 github.com/andygxzeng/Bon…

Review from the lab on lipid metabolism in AML just out @LeukemiaJnl rdcu.be/em651 Led by the hard work of @VilmaDembitz and @sophiejamess_ Hope you enjoy the read!

Register now for the FEBS Workshop on the Molecular and Cellular Pathways of Aging in Hematopoiesis that will take place in Crete on October 20-24, 2025! To register visit: …inginhematopoiesis2025.febsevents.org

Interested in single cell genomics but need help getting started? Check out my lab's Single Cell Genomics Day on April 25. Talks will feature recent exciting computational and experimental advances and will be live-streamed at satijalab.org/scgd. Please RT/spread the word!

Fantastic talk from Dr. Zheng from the @QuekLab on the role of TP53 mutations in CH-associated dyserythropoiesis and OxPhos alterations!

So happy to present our work at the #ASH24! I’m very honoured to be a recipient of the abstract achievement award this year. Many thanks to all the collaborators involved in this project @SchuringaLab @QuekLab @FrezzaLab @jeansarry

Fantastic talk from Manuela at #ASH2024 on the role of autophagy in FLT3-inhibitor therapy in AML! Great collaboration of the Traina Lab at @fmrpusp and @SchuringaLab ! Very well done!

Great ending for the first day at #ASH2024 with this group that keeps growing every year! Great to see you all! @SchuringaLab @QuekLab

We are at the #ASH2024! Check out today poster #1393 about the role of lipid metabolism in metformin sensitivity in AML from @dominiqueasr and #1539 with the mechanisms of MLL5-driven leukemic transformation from @luisesimoes

Why do AML patients with African ancestry have poor outcomes? Fascinating results indicate that genetics alter AML biology. Also, its Bailee Kain's first co-first author postdoc pub. @Bailee_Kain @AkEisfeld @nsalomonis and Elaine Mardis nature.com/articles/s4158…

CH in Telomere biology disorders as predictors of #MDS! As Chr1q+, U2AF1-S34 leads to TP53 pathway deregulation in HSCs with dysfunctional telomeres. Now online! #TBD #clonalHematopoiesis

🔎 Investigators with Dr. @VilmaDembitz at @QMBCI identified stearoyl-CoA desaturase as prognostic of patients' outcomes and showed that SCD inhibition ⛔ is a therapeutic vulnerability across multiple #AML models. @LeukemiaJnl | go.nature.com/4g44ssH

WE’LL NEVER FORGET THIS MOMENT 🥹 An all-Black podium graces #OlympicGames gymnastics for the first time ever.

This is everything.

Wish you could quickly analyze your #singlecell data? Or easily share these large datasets with collaborators? Good news! We just launched our free web-based app 10x Genomics Cloud Analysis globally! Sign up now or explore a guided walkthrough: bit.ly/4cpHhae

Finishing #EHA2024 with this amazing opportunity to present our latest results on MN1-driven AMLs! Very grateful to the @EHA_Hematology scientific committee, to my mentor @SchuringaJan and all the members of the @SchuringaLab, @QuekLab and #RegoLab that contributed to this story!

Amazing talk summarizing all the old and new directions regarding mitochondrial/lipid metabolism in drug resistant AMLs from @jeansarry at #EHA2024!

Fantastic talk from @SchuringaJan on the latest data from the @SchuringaLab about the metabolic heterogeneity in AMLs and the role of the tumor microenvironment on metabolic abnormalities/adaptation in AML at #EHA2024!

I am very grateful to the @young_eha committee for this opportunity to share this great collaborative work from the @SchuringaLab, #RegoLab, and @QuekLab on metabolism in AML! Looking forward to the next talks at #EHA2024!

Proud of the work by Dorien Pastoors and the rest of my fantastic team and collaborators. Read it in "Science Advances"! Oncogene EVI1 drives acute myeloid leukemia via a targetable interaction with CTBP2 pubmed.ncbi.nlm.nih.gov/38748792/