Daniel Bejan
@dannybejan
Postdoc - ADC Chemical Biology @Pfizer PhD - Chemical Biology @OHSU | Cohen Lab
I am thrilled to share the first chapter of my PhD on the “Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor” hot off the press from @ChemicalScience! #MyFirstChemSci pubs.rsc.org/en/content/art… A short 🧵 below on the study
I'm excited to share the final version of this story published in @embojournal Check it out! embopress.org/doi/full/10.10…
Attention PTM aficionados ‼️ Why have one PTM on a single amino acid when you can have two! We show that PARP10 mono-ADP-ribosylation is further ubiquitylated in cells! An exciting collaboration between the labs of @MichaelNADbio and @jnpruneda! Short thread below 🧵
Chemical #probes are important tools for validating drug targets. Covalent inhibitors & molecular degraders are expanding the druggable space. We now propose quality criteria for covalent & degrader probes: @ACSBioMed pubs.acs.org/doi/pdf/10.102… @Chemical_probes @thesgconline #TPD
I'm pleased to share my recent first-author work in the @MichaelNADbio Lab published recently in @CellChemBiol describing a selective PARP7 inhibitor, KMR-206. A short thread on our findings below: cell.com/cell-chemical-…
We're hiring for two Research Assistant and two Postdoctoral Research positions! Applicants with backgrounds in cancer biology, biochemistry, immunology and/or nanoparticles are encouraged to apply! See our website for details: pdxpharm.com/career-opportu…