ChemRxiv Bio and Med Chem

Efficient photo-release of hydrogen sulfide (H2S) from stable water-soluble precursors ift.tt/HIlFnCL #chemrxiv_biochem

N-terminal protein-macrocycles enabled by conjugate addition/ring expansion cascade reactions ift.tt/CbkZWPB #chemrxiv_biochem

ChainSpace: Sequence-Aware Design for Machine Learning-Driven Polymer Engineering ift.tt/wLSaoWc #chemrxiv_biochem

Taxol and Camptothecin: Chemistry, bioactivity, and biological production ift.tt/Vydorw8 #chemrxiv_biochem

Molecular Insights into Zymomonas mobilis Membrane Interactions with Lignocellulosic Inhibitors ift.tt/DL6Qkur #chemrxiv_biochem

Engineering artificial metabolic pathways within live mammalian cells through the integration of enzymes and transition metal catalysts ift.tt/hWdlpXs #chemrxiv_biochem

Leveraging a Large-Scale Experimental Database of Ruthenium Complexes to Predict Cytotoxicity for Anticancer Purposes Using Machine Learning ift.tt/0B4QlXs #chemrxiv_biochem

The discovery of Abl kinase ATPase activity and its implications in the development of straightforward assays ift.tt/yh8PYC9 #chemrxiv_biochem

Expanding Chemical Space of N-Acyl Sulfonamides for Carbonic Anhydrase Inhibitor Discovery ift.tt/1iIy3bZ #chemrxiv_biochem

Molecular Origins of Simultaneous Chemo-, Enantio-, and Substrate Selectivity in Photoenzymatic Radical Reactions ift.tt/R7LEsiX #chemrxiv_biochem

Synthesis of benzo[b]thiophene 1,1-dioxides via Pd-catalyzed sulfinylation of aryl triflates and their use as large Stokes shift fluorophores for multicolor live-cell imaging with self-labeling tags ift.tt/TbtXnQW #chemrxiv_biochem

Predicting the thermodynamics and kinetics of protein-protein interaction from spontaneous association simulations ift.tt/hWuG5xq #chemrxiv_biochem

Fluorogenic squaraine dimers for the flow cytometry detection of urinary tract infections ift.tt/K7f3oSB #chemrxiv_biochem

Photocleavable Systems for Cell Biology: Conceptual Design across Molecular Modalities ift.tt/bHwnj8O #chemrxiv_biochem

Selection of Ruthenium Polypyridyl Complex-modified Aptamers for Photodynamic Therapy against Streptococcus pneumoniae ift.tt/NvWx2dr #chemrxiv_biochem

Identifying persistence in enzyme kinetics and growth dynamics using the a-m model ift.tt/SNgFHyu #chemrxiv_biochem

Biosynthesis of the Biphenomycin Family of Potent Antibiotics ift.tt/b5tuyKc #chemrxiv_biochem

Click-to-release for controlled immune cell activation: tumor-targeted unmasking of an IL12 prodrug ift.tt/72HhZQv #chemrxiv_biochem

A Small Molecule Substrate Mimic to Inhibit Bacterial Hsp70 Chaperone Function ift.tt/19nSkvC #chemrxiv_biochem

Boosting NAD+ for Anti-Aging: Mechanisms, Interventions, and Opportunities ift.tt/5SwkzDQ #chemrxiv_biochem