Chaz Hong MD PhD 🇺🇸

Acidic tumor environments promote cancer cell survival and treatment resistance. Here, we show that proton-receptor GPR68/OGR1 mediates a crucial glioblastoma survival signal. We also report novel OGR1 inhibitor named Ogremorphin, which induces ferroptosis in all glioblastoma…

Yah! #Dorsomorphin came from #zebrafish screen for sure! I found it! Thanks for sharing! @ZebrafishRock

Did you know Parke-Davis (now Pfizer), the drug company responsible for Epinephrine, Coley's toxins (first cancer vaccine), Ketamine, Dilantin, Neurontin & PCP (yikes!), was founded in #Detroit? Here's a postcard of manufacturing center that still stands as a part of…

“cutting nearly $1 trillion from Medicaid, a lifeline for rural hospitals & families, is not thoughtful policy. “One Big Beautiful Bill”…threatens to undermine the very foundation of care in rural communities that are already underserved.” ⁦@bfrist⁩ usnews.com/opinion/articl…

While I couldn’t be there, the Hong group, along with Ruya Liu lab, was well represented at the #2025BCVS meeting in Baltimore! Daniela Fuller presented her tour de force PhD work on small molecules that selectively promote human cardiomycyte proliferation without disrupting…

Some of the very best trainees I have known are IMG’s, but what about equally qualified US college graduates who were blocked from their goal of becoming a physician to their neighbors or physician scientists due to exorbitant costs & extremely competitive admissions of US…

Holy cow! It looks like Eli Lilly took a $2B gamble & won. In a potentially huge news for our patients suffering from muscle loss due to heart failure, malignacy or just hip fracture, bimagrumab was shown to help people lose fat AND gain muscle at the same time. Eventually,…

NIH Ends Funding for Animal-Only Studies. Having just served as the Chair of the first NIH #Complement_ARIE study section to promote development of human-based #NAMs (New Approaches Methodologies), I am just as stunned as everyone that NIH announced it will no longer fund…

The Hong group made a strong showing at the International #Zebrafish Meeting at @UWMadison. Dr @cwilliamszf presented his groundbreaking work on visualizing extracellular acidic domains in live animals, with implications for #musculardystrophy. Dr. Leif Neizel showcased our…

Medicine without Science is Quackery. Evidence before Testimonials. #ResearchSavesLives @MSUMD @MSU_Medicine @michiganstateu

We @HFH_MSU_HS are hiring CANCER scientists. This is on top of what @MSUMD @MSU_Medicine is already doing. Be a part of transformative growth of @michiganstateu & @HenryFordHealth in the heart of a resurgent #Detroit! #SpartansWill For more info, follow the link:…

More silliness while trying not to lose my mind writing a NIH grant, knowing the chances just fell through the floor thanks to the "Big Beautiful Bill." Drove a red light, so had to take Driver's Ed Refresher course. Michigan's state department offers dozens of online refresher…

Happy July 4th from Boston's Esplanade --> where the bike paths are dedicated to Dr. Paul Dudley White for his advocacy for preventive cardiology

Building Future of Health on History of Discovery. To cardiologist like me, @HenryFordHealth is distinguished for its contibrutions to our field. For example, did you know pioneering cardiac surgeon Conrad Lam (@YaleMed ‘32) was first in the world to use purified heparin to treat…

Thank you, @MSUMD⁩ Dean Aron Sousa, for bringing common sense to #GunViolence discussion. For physicians, who deal with broken bodies, tackling gun violence IS “our lane.” humanmedicine.msu.edu/news/aron-sous…