calliecoombs
@calliecoombsmd
Associate clinical professor at UC Irvine focused on CLL/SLL with side interest in CHIP/CCUS. Animal and nature lover. Tweets are my own.
The real value of events like Great Debates in Hematologic Malignancies? The people. Conversations in the hallways, shared insights over coffee, and clinicians from all backgrounds coming together to challenge perspectives. Scroll through for a look at the moments and the…
Looking forward to the meeting tomorrow!
The wait is almost over. Great Debates in Hematologic Malignancies kicks off tomorrow in Los Angeles! We’re looking forward to a weekend of dynamic debates, practical takeaways, and clinical connections you won’t find anywhere else. #Hematology #cancercare #oncology #GDHEM…
The wait is almost over. Great Debates in Hematologic Malignancies kicks off tomorrow in Los Angeles! We’re looking forward to a weekend of dynamic debates, practical takeaways, and clinical connections you won’t find anywhere else. #Hematology #cancercare #oncology #GDHEM…
I sometimes like to think I’m a good dresser but I will never be able to top Dr. Birhiray #fASHion - great visit to Indy!

Yikes these are sobering data - well done @BrianHill_MDPhD
Very proud of my @ClevelandClinic mentor Dr. @BrianHill_MDPhD and former co-fellow Dr Taylor Brooks (@RoswellPark contributed) and their large study on outcomes with BSAbs in #DLBCL. Great option but more research greatly needed especially post #CART #lymsm
Bravo @KellyLBolton - can’t wait to read this!
Very proud of my @ClevelandClinic mentor Dr. @BrianHill_MDPhD and former co-fellow Dr Taylor Brooks (@RoswellPark contributed) and their large study on outcomes with BSAbs in #DLBCL. Great option but more research greatly needed especially post #CART #lymsm
Great to see the long-term results, still remember when the study was open when I was at UNC, great work @cedittus1 and @Jmarksloan!
Have been working w/ @Jmarksloan on this for a decade: BV-CHEP for 1L ATLL. @BrJHaem N=16 CR: 62.5% ORR: 87.5% mOS: 15.7m AlloSCT: 5 pts; mOS: NR Tox: cytopenias, mucositis, PN New consideration for aggressive ATLL. onlinelibrary.wiley.com/doi/epdf/10.11…
It’s my first time attending a “Great Debates” meeting but really learning a lot from some great educators - @LymphClinician, John Leonard, Morton Coleman, and now to brush up on lower risk MDS with Dr Shastri! @GreatDebatesCME #GDHEM

FDA Eliminates REMS for Chimeric Antigen Receptor (CAR) T cell Immunotherapies. Pts now only need to remain close to CAR T facility for 2 weeks (no longer 4 weeks) and avoid driving for 2 weeks (no longer 8 weeks) following CAR T. Huge access improvement! fda.gov/vaccines-blood…
1/ Excellent news for 🇺🇸 patients receiving CAR-T therapy! FDA has listened to data and relaxed CRS monitoring and driving restrictions for liso-cel for #lymsm / ide-cel for #MMsm. Huge step to lower time toxicity and disparities. Can this be fixed for all CAR-T products?
Oh no! This is beyond disappointing 😟
Long awaited results of #VERONA (PH3 of aza-ven vs aza) in higher risk MDS press release with negative top line results for OS. We unfortunately remain in the dreaded boulevard of broken dreams in higher risk #MDSsm. Subgroup analyses will be important. news.abbvie.com/2025-06-16-Abb…
Wow first and maybe only time I’ll be called an influencer 😎 (majority of my views were from fan girling the LGL leukemia oral) #EHA2025
#EHA2025 #mmsm #amlsm #leusm #cllsm #lymsm @Eddie_Cliff @doctorpemm @Larvol @calliecoombsmd @FadiHaddad_MD @mtmdphd @sanamloghavi @tamaciro @OncoAlert
This was definitely one of the most enjoyable filmings I’ve done in a while - what a great crew! @mshadman @OncLive #EHA2025 #EHA25 🤣😭

CLL13 longer follow up - huge study and great presentation. Though GIV is superior, I would not use as SOC since the duration of therapy is longer (range 12-36 months) than ven/obi which is still quite excellent (and always 1 yr). And yes MRD still matters! #EHA25 #EHA2025




This was an amazing effort and practice changing study for LGL leukemia - cyclophosphamide is superior to MTX with respect to ORR with comparable safety - took 10 years to accrue but shows can do RCT in rare hem diseases #EHA25 #EHA2025




Not sure when will officially roll out but I think will be a good change (less pills/smaller pills?) once the initial annoyance of calls from pharmacies is over #cllsm
The @US_FDA has approved a tablet formulation of zanubrutinib across 5 hematologic indications. | @FDAOncology cancernetwork.com/view/fda-appro…
Pleasure to co-chair the rapid oral session with @DrLaCasce - saw some great data. Just like the lights in room E450a, the future is bright for CLL and NHL 😎 #ASCO2025 #ASCO25 @mshadman

Whoa this is huge! Can’t wait to read
New evidence today @NEJM that age-related clonal hematopoiesis (CHIP) has a driver role in evolution of solid cancers nejm.org/doi/full/10.10… nejm.org/doi/full/10.10…
Was already a Shingrix fan but this is more info to put the icing on the vaccine cake (though I still think hard to accept if it’s a true causal link) #cllsm
New @JAMA_current Another new report (natural experiment) shows the link of a vaccine vs shingles to less dementia jamanetwork.com/journals/jama/…
45 M. Asymptomatic Inc enl LN in root of mesentry Excisional LN bx shows- grade 3A follucular + potential castelman BM bx neg PET- Isolated LN Tx? @AaronGoodman33 @OncBrothers @calliecoombsmd @RenoHemonc @brunolarvol @PallawiTorkaMD @MadihaIqbal13