Ozren Bogdanovic
@bogdanoviclab
Principal Investigator at http://www.cabd.es | developmental epigenomics | Coordinator of the DANIO-ReCODE MSCA DN | https://danio-recode.eu | http://www.bogdanoviclab.org
New lab preprint - an awesome collaboration with @jjtenagu lab and @A_RuizHerrera and @malmuedocas labs is just out - check out the regulatory dynamics of zebrafish spermatogenesis 👇
Ever wondered how sperm are formed? Spermatogenesis is a microscopic marathon that starts in the testes and ends with fully functional sperm! Our new preprint biorxiv.org/content/10.110… takes a deep dive into zebrafish spermatogenesis, mapping out every fascinating step. 🧵👇 1/7
New preprint from the Lab at @cabimer. We present PLAMseq, using TurboID to do like ChIPseq and proximity proteomics in the same protocol with extra powers like mapping protein interactions in the genome. biorxiv.org/content/10.110…
Ever wondered how sperm are formed? Spermatogenesis is a microscopic marathon that starts in the testes and ends with fully functional sperm! Our new preprint biorxiv.org/content/10.110… takes a deep dive into zebrafish spermatogenesis, mapping out every fascinating step. 🧵👇 1/7
This preprint is now published with some key additions guided by an excellent review process @NAR_Open. Also grateful to our collaborators for helping progress this one across the finish line! @suscla1 @qianthefirst @Yael_David__ @zhouwanding and others! academic.oup.com/nar/advance-ar…
1/ Can we control how cells sense external stimuli by modulating their epigenetic states? 🧬🧪 Our latest study shows that targeted DNA methylation editing can shape cell fate & inflammatory responses in immune cells-now out in @ScienceAdvances! 👇 science.org/doi/10.1126/sc… 🧵:
We're hiring! Need a microscopy wizard to help build the world’s first synthetic plant chromosome! Bring your lights, lasers, & lens-craft to characterise new artificial chromosomes. Join our ARIA-funded project at @uwanews in Perth & @plants4space. Apply: bit.ly/3GKSRSA
I am grateful to receive a @ZonMw PSIDER TOP grant to investigate differences during human female and male pre-/peri-implanatation stages, using blastoids. A 2y postdoc position (from Aug/Sep; possible extension) will open soon, feel free to contact me! projecten.zonmw.nl/nl/project/sex…
Save de date! Join us at @cabimer on October 17th for the @GenomaHubCSIC Workshop in "Genome Dynamics in Development and Disease". Slots available for talks! Registration opens soon!!
SWARM (Single-molecule Workflow for Analysing RNA Modifications) detects pseudouridine, m6A, and m5C on individual molecules from direct RNA nanopore signals (in both chemistries RNA002 and RNA004) github.com/comprna/SWARM see more on poster P2-396 at #rna2025 #RNA25 #RNAmods
Finally out in Nature our collaboration with the Velten Lab 🥰 Enjoy the reading! nature.com/articles/s4158…
A triumph of perseverance from twitterless Tom Weber, Christine Biben and the team, our in vivo barcoding "LoxCode mouse" used to resolve epiblast fate to fetal organs is finally published in @CellCellPress and available to import through @jacksonlab sciencedirect.com/science/articl…
Magnificent talk today at #CABDseminars by Dirk Schüleber! Dirk explained the studies of his team understanding how transcription factors work as sensors and modifiers of chromatin. Prof. Schübeler was hosted by @bogdanoviclab, one of the first lab members. Thanks for coming!
Great pleasure to host @SchubelerLab this Friday - if in the Seville area, please join for what promises to be an incredible seminar!
#CABDseminars "Finding your place: Transcription factors as sensors and modifiers of chromatin" by Dirk Schübeler, Friedrich Miescher Institute @FMIscience 🗓️April 11th ⏰ 12 pm 📍Rosalind Franklin auditorium at CABD Hosted by @bogdanoviclab
Introducing cornetto, an adaptive genome assembly paradigm using @nanopore adaptive sampling. - greatly reduces cost per genome assembly - reference agnostic, so works for non-humans - assembly just using saliva - & many more Relies on 2 excellent software #readfish & #hifiasm.
Adaptively integrated sequencing and assembly of near-complete genomes biorxiv.org/content/10.110… #biorxiv_genomic
First seen in Biorxiv and now published and updated with more data in @NatureComms. With this work we have further enhanced CRISPR-Cas RNA targeting in vivo using transient approaches such as RNP or mRNA-gRNA in zebrafish embryos as vertebrate model. nature.com/articles/s4146…
Thrilled to share that our new preprint is out on @biorxivpreprint! Enhanced RNA-targeting CRISPR-Cas technology in zebrafish performed at the Moreno-Mateos lab @crisprscan @CABD_UPO_CSIC. A thread (1/13): biorxiv.org/cgi/content/sh…
Excited to share our #multiomics study of who was the world's #oldest living person! Our research on this record-breaking #supercentenarian suggests that, under certain conditions, #aging and #disease can become decoupled—challenging the common belief that they are inherently…
🚨 New paper alert 🚨 Our Human Microglia Atlas (HuMicA) characterizes #microglia subpopulations across 6 distinct #neurologic diseases. @RMartinsFerr @calafell_p @CarrerasIJC nature.com/articles/s4146…
Thrilled to share our milestone collaboration with Alán Aspuru-Guzik, Alex Zhavoronkov, Insilico Medicine, and our teams at UofT and the UAE! Using quantum computing to design KRAS inhibitors brings the future of drug discovery closer. Excited for what’s next!
Big Day, Ladies and Gentlemen - Welcome our new paper with @A_Aspuru_Guzik , @stagljar , Mohammad Ghazi Vakili and other giants where we show the first application of a real IBM Quantum Computer for generation of new KRAS inhibitor synthesized and tested. And while I do agree…
📣 Hiring, please forward widely!! Two postdoc openings to work on genomics of diabetes 1. computational regulatory genomics/statistical genetics. 2. Experimental cell-based modeling DM if interested @CRGenomica shorturl.at/O3wMi shorturl.at/ieyZy
Great highlight of our work but it is big team effort. I can’t take full credit for it :) onconaut.ai/about
“Onconaut,” an #AI-based online tool that #mdcBerlin's @AltunaAkalin has developed, helps oncologists and patients to find the most up-to-date and tailored treatment possible. @helmholtz_ai has now recognized it as the “Best digital resource.” More: mdc-berlin.de/news/news/navi…