Juewen Liu
@bionaloo
Professor of Chemistry at UWaterloo working on #Aptamers #DNAzymes and #Biosensors. Editor of Biosensors & Bioelectronics, TrAC, CCL, and FACETS.
A beautiful dopamine aptamer structure biology talk by Prof. Cameron from @univbordeaux_EN, followed by a joint group meeting with five students from the @philip_johnson8 group from York University. A nice aptamer day! @uWaterlooIntl
Led by PhD student Yachen Xie, we obtained aptamers for bilirubin and biliverdin. Took us two years, a lot of details, check it out! Nice NMR from @philip_johnson8 and @RahithNY pubs.acs.org/doi/10.1021/ac…
I think this is the first time that Irving-Williams series is seen in a nucleic acid. Should be an interesting metal binding site. Check out our new paper @ChemicalScience, another good collaboration with @philip_johnson8 and @RahithNY pubs.rsc.org/en/content/art…
Happy to share our review paper on recent #aptamer selection work, #SELEX and #biosensors published in TrAC. Open access! sciencedirect.com/science/articl…
Farewell lunch for a Turkish couple visiting professors, Esra Bagda and Ekfan Bagda, from Sivas Cumhuriyet University. They stayed for two years and started aptamer work on modified nucleosides such as methyladenosines. Thank you and it was great to have you in the lab.
Had a great #CSC2025 conference with 10 lab members who made it to Ottawa. Many great talks and super high enthusiasm even on the last day. Our aptamers have gained popularity 👏👏
It was great to have you in my lab, Amal 👏
Another fantastic PROMOTE Trainee Exchange. Congrats Amal Mathai! @NSERC_CRSNG , @bionaloo @Yingfu8888
Sharing a black and gold umbrella with Prof. Kejian Ding after giving a talk to students of our 2+2 students at Beijing Jiao Tong University 😀
Had a great time in the GWC2 annual meeting with 11 lab members, and gave a talk on aptamers binding to everything 😀
Our aptamer for acrylamide has only mM affinity. After reacting acrylamide with xanthydrol to form a covalent adduct, a new aptamer with nM affinity for the adduct was obtained. Published @an_chem pubs.acs.org/doi/full/10.10…
Four of our papers ranked as most widely read papers in Wiley publications, topics ranging from aptamers, microplastics to nanozymes. 👏👏
We found an aptamer that can bind to lanthanides. Check it out, open access! pubs.rsc.org/en/content/art…
Glad to see the structure of our theophylline DNA aptamer solved by crystallography by Prof. @LinHuang2008. A beautiful structure 👍👍 From Theophylline to Adenine or preQ1: Repurposing a DNA Aptamer Revealed by Crystal Structure Analysis onlinelibrary.wiley.com/doi/10.1002/an…
About to start my gold nanoparticles and aptamer talk at Pittcon👏👏
Our microplastic aptamer paper is among the most accessed papers last month 👏👏
The most accessed papers in December include contributions by @RovisGroup, @grykogroup, @GloriusGroup, @ZhangLabOSU, @jagadeesh_group and @bionaloo. Check them out and more. ow.ly/eCKU50UCq3I
Glad to see our new @J_A_C_S paper online on New Year Day! Using Sc3+, a visiting PhD student Jin Wang obtained an aptamer with different affinities and binding and dissociation kinetics to rare earth metals. Thanks @philip_johnson8 and @RahithNY for NMR! doi.org/10.1021/jacs.4…
Our new paper reveals a huge effect of pH in isolating aptamers for Kanamycin. At pH 6, we got highly enriched aptamers, but not at pH 8, which seems reasonable considering the four pKa values of Kanamycin being all close to 7. …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/an…
Farewell lunch. Six visiting students and scholars, Xun Wang, Yiting Wang, Cin Luo, Xin Wang and Li Zou) will leave my lab recently (Jin Wang already left). They have contributed tremendously to the lab, expanding our aptamer research to rare earth metals, and RNA. Thank you!
