Andy Lawrence (@biomimetic_chem)

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Andy Lawrence@biomimetic_chem · Apr 30

The dienone–phenol rearrangement has been known for 100+ years and is a staple of undergraduate courses (migratory aptitudes!). Today we report on its lesser-known cousin: the quinol–enedione rearrangement. pubs.acs.org/doi/10.1021/ac…

biomimetic_chem's tweet card. The quinol–enedione rearrangement enables the synthesis of 2-cyclohexene-1,4-diones from readily available para-quinol substrates. Building on sporadic early reports of this transformation, we have...

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School of Chemistry | University of Melbourne@ChemistryUoM · Jul 10

** Organic and Biological Chemistry Seminar ** Professor Andy Lawrence @biomimetic_chem University of Edinburgh @EdinburghChem "Synthetic Strategies and Concepts Inspired by Natural Products" Wednesday 20 August | 11 AM-12 PM | Bio21 Auditorium ALL WELCOME!

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PRS-Group@prsgroupjlu · Jun 11

So excited the team has made a nitrogen allotrope! Check it out here: nature.com/articles/s4158…

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Mingji Dai@MingjiDai · May 14

Always appreciate such message from @ACSPublications @J_A_C_S. Glad to see that "Article views" numbers are valued! This is important for a field such as total synthesis, which doesn't get cited often, but attracts a lot of readership! Here is the paper: pubs.acs.org/doi/10.1021/ja…

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Alex Zografos@zografos_alex · May 13

Do you want to uncover Nature's secrets for guaianolides? Check our latest publication! Many congrats Maria for the excellent work! Decoding Guaianolide Biosynthesis: Synthetic Insights into Pseudoguaianolides and Seco-Guaianolides pubs.acs.org/doi/10.1021/ac…

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Hall Research Group at UAlberta@HallBoronLab · May 12

This week's Paper-of-the-Week (POW) presentations in our weekly group meeting featured some fantastic work by @biomimetic_chem + @rafal_szabla, Kan group + Li group + Wu group, Chen group + Wang group and @SarlahLab! #Chemistry #Boron

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Perry Group@PerryChem · May 6

📢 Come join us in sunny Southampton ☀️ The opening for our Postdoctoral Research Associate in Organic Synthesis is now live! jobs.soton.ac.uk/Vacancy.aspx?r… Deadline: Thurs 29th May 2025 Start date: Flexible – anytime from now to early 2026 @UoSChem_ChemEng @unisouthampton

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Andy Lawrence@biomimetic_chem · May 5

>30 years since anyone reported on the quinol–enedione rearrangement. Truly remarkable to see @GVincentUPSUD & Prof. Zhaoyong Lu report beautiful total syntheses using this reaction at the same time as our paper! Vincent: onlinelibrary.wiley.com/doi/full/10.10… Lu: chemrxiv.org/engage/chemrxi…

AAndy Lawrence@biomimetic_chem · Apr 30

The dienone–phenol rearrangement has been known for 100+ years and is a staple of undergraduate courses (migratory aptitudes!). Today we report on its lesser-known cousin: the quinol–enedione rearrangement. pubs.acs.org/doi/10.1021/ac…

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Nature Reviews Chemistry@NatRevChem · Apr 13

A career in pursuit of the fundamentals nature.com/articles/s4157… 🧪

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Laszlo Kurti@kurtilaszlo · Apr 18

We’re excited to share our work that introduces singly N-protected O-vinylhydroxylamines as ring-annulation reagents for the synthesis of azaindolines and azaindoles. Congrats to Zach & Charlotte (@charlie_bird13) and the Enamine (@EnamineLtd) team! 🔗 chemrxiv.org/engage/chemrxi…

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Jamie Docherty@JDawklol · Apr 2

🚨New Paper Alert - Thrilled to share our latest work now online in @NatureCatalysis! We report regiodivergent ruthenium-catalysed C-H functionalisation reactions to install versatile silylmethyl handles with pristine precision. 👉 [nature.com/articles/s4192…]

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Andy Lawrence@biomimetic_chem · Mar 28

Check out the first total synthesis of brevianamide S. Congratulations Adam and the whole team! Spoiler: We didn't follow a biomimetic approach...we opted for a more flexible three-component coupling strategy. pubs.acs.org/doi/10.1021/ac…

biomimetic_chem's tweet card. The first total synthesis of the alkaloid brevianamide S has been achieved in eight steps. This natural product, isolated from Aspergillus versicolor, exhibits selective antibacterial activity...

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Andy Lawrence@biomimetic_chem · Mar 28

Just one week left to apply for both of these #TotalSynthesis PhD studentships (UK applicants only) to join our group @EdinburghChem.

AAndy Lawrence@biomimetic_chem · Mar 10

We have 2 PhD studentships available (UK students only). Deadline: 4 April 1. Machine Learning-Guided Synthetic Strategies for Natural Product Synthesis, with @KingSmith_Group. findaphd.com/phds/project/m… 2. Biomimetic Total Synthesis of Natural Products. findaphd.com/phds/project/b…

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Andy Lawrence@biomimetic_chem · Mar 19

A postdoctoral position, funded by the @LeverhulmeTrust for up to 36 months, is available to join my group @EdinburghChem . The project focuses on biomimetic approaches to natural product synthesis. Deadline: 18th April 2025. elxw.fa.em3.oraclecloud.com/hcmUI/Candidat…

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Andy Lawrence@biomimetic_chem · Mar 10

We have 2 PhD studentships available (UK students only). Deadline: 4 April 1. Machine Learning-Guided Synthetic Strategies for Natural Product Synthesis, with @KingSmith_Group. findaphd.com/phds/project/m… 2. Biomimetic Total Synthesis of Natural Products. findaphd.com/phds/project/b…

biomimetic_chem's tweet card. PhD Project - Biomimetic Total Synthesis of Natural Products at University of Edinburgh, listed on FindAPhD.com

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Pulis Group@PulisGroup · Jan 7

🚨4-year fully funded PhD studentship available in organoborane catalysis (via EPSRC DLA). Get in touch with me for a chat! findaphd.com/phds/project/n…

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Thomas Group@SPThomasGroup · Jan 6

A nice holiday present for us! Our most recent article has been accepted Angewandte @angew_chem. Read it at the link below. doi.org/10.1002/anie.2…

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Andy Lawrence@biomimetic_chem · Jan 6

Congratulations to Dr Vera Demertzidou (@VDemertz) on creating a fantastic Synthesis Workshop Research Spotlight video on our new approach to enantioconvergent reactions, originally published @NatureChemistry (nature.com/articles/s4155…)!

SSynthesis Workshop@MatthewHorwitz1 · Jan 4

Join us as we start the new year on Synthesis Workshop with a Research Spotlight talk by Dr. Vera Demertzidou on stereoretentive enantioconvergent reactions!! Link: youtu.be/bjE4ZUPlSvo Key paper:@NatureChemistry 2024, 16, 1177–1183. doi.org/10.1038/s41557… @biomimetic_chem

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Synthesis Workshop@MatthewHorwitz1 · Jan 4

Join us as we start the new year on Synthesis Workshop with a Research Spotlight talk by Dr. Vera Demertzidou on stereoretentive enantioconvergent reactions!! Link: youtu.be/bjE4ZUPlSvo Key paper:@NatureChemistry 2024, 16, 1177–1183. doi.org/10.1038/s41557… @biomimetic_chem

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Sunkyu Han@hanpisa · Dec 12

Total synthesis of (−)-flueggenine A and (−)-15′-epi-flueggenine D - now published in @ChemicalScience pubs.rsc.org/en/content/art… Congrats to Seung Mo (1st author), Dr. Kim Dongwook (Crystallographer), and Taewan (calculation). @KAIST_Chem #totalsynthesis

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