Berger Lab
@berger_lab
Our laboratory @Penn studies epigenetic regulation in a variety of model systems. Tweets from lab members and not Shelley Berger unless signed SB.
Looking for a postdoc position studying epigenetics? The @berger_lab @PennEpiInst is hiring! We study how epigenetics regulates health & disease in a range of biological contexts, including behavior & learning, cancer, aging & neurodegeneration. Info here:tinyurl.com/4f9r32ry

We are excited to see our postdoc @tran_khoa paper out today in @MolecularCell! He finds that SIRT7 regulates NUCKS1 chromatin binding during senescence and aging! cell.com/molecular-cell…
ft. Katherine Alexander, @yu_ruofan Son Nguyen, @clfaunce Hua Huang, Joan Lim, @CatherineYLi, Nicholas Biddle, Eric Joyce, @berger_lab Nicolas Skuli, Nathan Coffey, Brian Keith, Celeste Simon, Austin Good, Daniel Lee @IanDardani & @arjunrajlab @PennEpiInst nature.com/articles/s4155…
New research from @berger_lab reveals that nuclear speckle patterns in kidney tumors may predict treatment response in clear cell #RenalCellCarcinoma. This discovery could guide personalized therapies, offering hope for improved outcomes. #KidneyCancer spr.ly/6013ayqbd
💫NEW by @berger_lab & co: #NuclearSpeckle (NS) constituents have 2 expression states in #cancer correlating with patient survival & HIF-2α functional programs. HIF-2α mediates NS association of key genes activated in renal cancer. rdcu.be/d56c7 nature.com/articles/s4155…
Thank you @PennMedicine for the highlight of our work looking at nuclear speckles in clear cell renal cell carcinoma. Read below 👇
New research from @berger_lab reveals that nuclear speckle patterns in #kidney tumors may predict treatment response in clear cell renal cell #carcinoma. This discovery could guide personalized therapies, offering hope for improved outcomes. spr.ly/6010vmwbw
Out this week in @NeuropharmJ. The first publication featuring an Egervari Lab member @eperiandri! sciencedirect.com/science/articl…
📢 JOB ALERT: Tvardovskiy Lab at @PennEpiInst is hiring at all levels! Interested in chromatin biology, quantitative proteomics, or epigenetic modifications? Learn more about our research and apply at tvardovskiylab.org Please RT
Yesterday, we celebrated our lab manager/resident ant whisperer and her future baby! Congratulations, Tierney! 🍼

Congratulations to our graduate student @PSamareh on a successful PhD defense! 🥂🥳


🚨🚨🚨We’re excited to give a Jumbo welcome to @tran_khoa, who’s joining Tufts Bio as an Asst Prof in Sept’25! Learn about Khoa and his research on metabolic-epigenetic crosstalk here: khoaatran.com/research
New CSHL Assistant Professor Katherine Alexander specializes in nuclear speckles (the proteins and RNA housed in the nucleus). Exploring their potential influence on gene regulation could lead to enhanced cancer patient outcomes. cshl.edu/katherine-alex…
Congrats to our recent graduates! @LinyangJ @DesiAlexander_


Congrats to Dr. Alexander on a successful thesis defense! You crushed it! 🥂 @DesiAlexander_



Excited to share our recent manuscript on histone acetylation in Alzheimer’s disease! This work was led by our recent PhD graduate student @danielcxu Congrats to all! 👏🏻 actaneurocomms.biomedcentral.com/articles/10.11…
Congratulations to our undergraduate researcher Amina Khasanova for receiving the University of Pennsylvania's Endowed Dean’s Research Award!

Congrats to our graduate student @LinyangJ for his successful PhD defense! 🥂


A bittersweet goodbye to our postdoc Zhen Zhang who is off to start his on lab! Congrats and best of luck Zhen! 🥂

We are so proud of our postdoc @Laevorotatory for receiving the Kaushal award! Congrats Karl! 👏🏻
We're celebrating Karl Glastad and Daniel Park, recipients of the Kaushal Awards! Thanks to all who joined the celebration last Friday.