Apoorva
@apoorvasriniva
bits and atoms
👶💊new preprint: >40% of the prescriptions children receive are prescribed off-label. this is mostly because running pediatric trials is ethically and logistically hard. to bridge that gap, the FDA sometimes extrapolates adult data. yet, no public record tracks those…
i recently read for blood and money and i loved it. it is a wild story about two tiny biotech firms, Pharmacyclics and Acerta, that developed blockbuster drugs for chronic lymphocytic leukemia (CLL). they were both eventually sold for $7+ billion and generated billions in…
UPDATED:. Sarepta Therapeutics $SRPT crisis is huge blow to Duchenne families, company Company has refused FDA request that it pull gene therapy from the market following patient deaths statnews.com/2025/07/18/sar…
It’s wild to think that Sanger sequencing, which famously decoded the first 5,000-base genome of bacteriophage φX174, was invented almost half a century ago. The space has exploded with 10 companies and 37 instruments. If you factor in the different flow cell types and…
it was a complicated 17 hour surgery but they finally managed to separate the art from the artist
wait so does this mean we don’t have to invent bio driven tokenizers anymore
Tokenization is just a special case of "chunking" - building low-level data into high-level abstractions - which is in turn fundamental to intelligence. Our new architecture, which enables hierarchical *dynamic chunking*, is not only tokenizer-free, but simply scales better.
NEW: No technology currently exists to repair damaged brain tissue and fully restore lost function. FRONT aims to enable millions with what is considered permanent brain damage to regain lost functions, including motor control, vision, and speech. arpa-h.gov/news-and-event…
Today, the FDA published more than 200 decision letters, known as complete response letters or CRLs. CRLs are issued directly to product sponsors when the FDA completes its review cycle and determines that it cannot grant an approval of an application in its current form. By…
Wow... The FDA just posted an archive of Complete Response Letters from 2020-2024 open.fda.gov/apis/other/app…
being a tour guide sounds like such a fun job. you can just make stuff up everyday
my italian waiter just told me “don’t eat so fast, slow down and enjoy it in a perfect way”
in pompei looking at mount vesuvius, named after the famous scrolls
you haven’t really experienced a city until you’ve walked around in it.. driving around in a vehicle doesn’t count
words can’t describe the overwhelming beauty of rome and the art in it
oh you work in bio? you mean the cursor of not making money?
excited to be at AIME 2025 in pavia, italy! i will be giving a talk tomorrow about auditing the reporting quality of over 20k RCT articles. i’ll then be frolicking around Italy until july 12th. DM if you’d like to meet or share recs!