Alejandro Montenegro
@aemonten
Molecular Biologist, PhD丨Chief Editor CSH Protocols & Head of Integrity in Publishing — @CSHL丨Scientific Chair @molbiosystems丨Central Dogma Police丨Chilean 🇨🇱
🚨IT'S HAPPENING!🚨 Register now and join us in beautiful southern Chile in September for a new edition of the Molecular Biosystems Conference! @molbiosystems
🚨 Registration for the Molecular Biosystems Conference is now OPEN! Join us to discuss cutting-edge research in gene regulation & functional genomics. 📅 Sep 29-Oct 3, 2025 📍 Puerto Varas, Chile 🔗 Register here: molbiosystems.com Register now—space is limited!
Poll results
If you were giving a talk, would you complain if you knew someone in the audience was using an AI tool to capture notes about your talk? I'd love to hear your thoughts!
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*Easter egg alert* NOT in the published paper. We also benchmarked Evo 2 and while it did better than other gLMs (consistent that scale can improve gLMs), it still falls short of a basic CNN trained using one-hot sequences and far short of supervised SOTA x.com/pkoo562/status…
I've just realized that this is essentially what Nature calls a "Tools of the Trade" article type. That's OK! Good ideas are worth repeating. If you are interested in writing one, let me know!
I want to create a "Behind the Paper"-like article for CSH Protocols, where authors would succinctly summarize a recent methods paper they've published in any journal. This can provide context & is a way for authors to directly connect with the community. Interested? Lmk!
If YOU were in charge of the English language for a day, what is one thing you would absolutely change?
If YOU were in charge of the English language for a day, what is one thing you would absolutely change?
At #mbiosys25, sessions start at 9 😊
True academic friendship is agreeing to sit in the audience for their 8:15am presentation
Auto-generated figures are now live (in beta) on Biographics! Upload a reference diagram and Biographics will try to recreate it using our open license library.
Nitro BioGraphics just hit 1000 users! Been working on lots of quality of life improvements as well as an exciting new feature coming very soon - stay tuned!
💯 PR for AI-oriented commercial research has now flooded multiple fields: variant effect prediction, perturbation prediction, single-cell integration, AI pathology, to name a few. Unfortunately, this has often led to surreal, incomprehensible papers. Some themes:
Social media has truly warped science consumption. On one hand it has massively democratized it. On the other hand, it's become extremely easy to use hype to simply amplify things that are simply not true. 1/
Yes yes I know. Most science has been hypey forever. But it's hyperaccelated now with this weird meld of academic science & startup culture + social media and highly skilled amplification by marketing & PR teams. 3/
"This study suggests the potential utility of generative AI in pre-institutional review board (IRB) review tasks" journals.plos.org/digitalhealth/…
Join us in LinkedIn!
We’ve just launched a LinkedIn group for the Molecular Biosystems Conference, a place not just to share updates about the meeting, but to create a space where researchers can connect, share opportunities, and keep the conversation going year-round. Join us! (link below)
#ThankYourEditor❤️
A special thanks to @DimitrisTypas for his efficient and thoughtful handling of our manuscript and the reviewers for constructive feedbacks to help us improve the manuscript.
🔬 Thrilled to announce that @epicypher is once again sponsoring #mbiosys25! EpiCypher is dedicated to creating novel platforms that support innovative epigenetics and chromatin research. Learn more below! epicypher.com
Financial, yes, but also personal sacrifices. For instance, not everyone can move (sometimes abroad) to join certain institutions, & the differential outcomes are not necessarily related to talent. journals.plos.org/plosbiology/ar…