Austin Gabel
@a_gabel2
#MdPhD student working in functional genomics @uwgenome @fredhutch (he/him)
Happy to share a new paper from work in @bradleybio lab demonstrating that APC is an RNA-binding protein that regulates poly(A) site selection. genomebiology.biomedcentral.com/articles/10.11…
I'm excited to share our collaboration with @AbdelWahablab @Doulatov_lab describing the RNA splicing factor GPATCH8, which plays a critical role in mis-splicing in MDS and leukemias with SF3B1 mutations! Led by @SBenbarche @jpineda223 @GalvisBaquero and just out in @MolecularCell
Excited to announce our paper out today in @MolecularCell discovering a novel splicing factor GPATCH8 and its requirement for pathologic splicing activity of mutant SF3B1. With @bradleybio & @Doulatov_lab. Led by @SBenbarche, @jpineda223, & @GalvisBaquero: cell.com/molecular-cell…
Excited to share our paper out today in @CellPressNews discovering RNA mis-splicing derived neoantigens & their cognate T cell receptors (TCRs) as well as characterization of endogenous neoantigen T cells in leukemia patients. authors.elsevier.com/sd/article/S00…
Excited to share the publication of our paper co-led by Won Jun Kim and myself. A big collaborative effort that was a joy to be involved in! Findings summarized in the thread below.
Excited to share our paper out today in @CellPressNews discovering RNA mis-splicing derived neoantigens & their cognate T cell receptors (TCRs) as well as characterization of endogenous neoantigen T cells in leukemia patients. authors.elsevier.com/sd/article/S00…